FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4321368590> ?p ?o ?g. }

• W4321368590 endingPage "30" @default.
• W4321368590 startingPage "21" @default.
• W4321368590 abstract "Long non-coding RNAs are a class of essential non-coding RNAs with a length of more than 200 nts. Recent studies have indicated that lncRNAs have various complex regulatory functions, which play great impacts on many fundamental biological processes. However, measuring the functional similarity between lncRNAs by traditional wet-experiments is time-consuming and labor intensive, computational-based approaches have been an effective choice to tackle this problem. Meanwhile, most sequences-based computation methods measure the functional similarity of lncRNAs with their fixed length vector representations, which could not capture the features on larger k-mers. Therefore, it is urgent to improve the predict performance of the potential regulatory functions of lncRNAs. In this study, we propose a novel approach called MFSLNC to comprehensively measure functional similarity of lncRNAs based on variable k-mer profiles of nucleotide sequences. MFSLNC employs the dictionary tree storage, which could comprehensively represent lncRNAs with long k-mers. The functional similarity between lncRNAs is evaluated by the Jaccard similarity. MFSLNC verified the similarity between two lncRNAs with the same mechanism, detecting homologous sequence pairs between human and mouse. Besides, MFSLNC is also applied to lncRNA-disease associations, combined with the association prediction model WKNKN. Moreover, we also proved that our method can more effectively calculate the similarity of lncRNAs by comparing with the classical methods based on the lncRNA-mRNA association data. The detected AUC value of prediction is 0.867, which achieves good performance in the comparison of similar models." @default.
• W4321368590 created "2023-02-21" @default.
• W4321368590 creator A5004115445 @default.
• W4321368590 creator A5015337971 @default.
• W4321368590 creator A5031311056 @default.
• W4321368590 creator A5033510051 @default.
• W4321368590 creator A5073973101 @default.
• W4321368590 date "2023-04-01" @default.
• W4321368590 modified "2023-09-27" @default.
• W4321368590 title "Measuring functional similarity of lncRNAs based on variable K-mer profiles of nucleotide sequences" @default.
• W4321368590 cites W1158178075 @default.
• W4321368590 cites W1966397536 @default.
• W4321368590 cites W2000875411 @default.
• W4321368590 cites W2002185065 @default.
• W4321368590 cites W2058659458 @default.
• W4321368590 cites W2070777085 @default.
• W4321368590 cites W2076627833 @default.
• W4321368590 cites W2077936018 @default.
• W4321368590 cites W2091161969 @default.
• W4321368590 cites W2112377187 @default.
• W4321368590 cites W2141831115 @default.
• W4321368590 cites W2343107734 @default.
• W4321368590 cites W2345181615 @default.
• W4321368590 cites W2416200080 @default.
• W4321368590 cites W2440793509 @default.
• W4321368590 cites W2512308096 @default.
• W4321368590 cites W2567796782 @default.
• W4321368590 cites W2735467708 @default.
• W4321368590 cites W2736736126 @default.
• W4321368590 cites W2739280501 @default.
• W4321368590 cites W2776508475 @default.
• W4321368590 cites W2777095407 @default.
• W4321368590 cites W2780392302 @default.
• W4321368590 cites W2783856602 @default.
• W4321368590 cites W2787822418 @default.
• W4321368590 cites W2793675769 @default.
• W4321368590 cites W2804071148 @default.
• W4321368590 cites W2890017579 @default.
• W4321368590 cites W2891866117 @default.
• W4321368590 cites W2895679848 @default.
• W4321368590 cites W2899830787 @default.
• W4321368590 cites W2939338720 @default.
• W4321368590 cites W2944230847 @default.
• W4321368590 cites W2954763649 @default.
• W4321368590 cites W3011173792 @default.
• W4321368590 cites W3013787003 @default.
• W4321368590 cites W3014160911 @default.
• W4321368590 cites W3035552353 @default.
• W4321368590 cites W3121770618 @default.
• W4321368590 cites W3147239170 @default.
• W4321368590 cites W3163379025 @default.
• W4321368590 cites W3173057190 @default.
• W4321368590 cites W3216248059 @default.
• W4321368590 cites W4220926354 @default.
• W4321368590 cites W611910056 @default.
• W4321368590 doi "https://doi.org/10.1016/j.ymeth.2023.02.009" @default.
• W4321368590 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36813016" @default.
• W4321368590 hasPublicationYear "2023" @default.
• W4321368590 type Work @default.
• W4321368590 citedByCount "0" @default.
• W4321368590 crossrefType "journal-article" @default.
• W4321368590 hasAuthorship W4321368590A5004115445 @default.
• W4321368590 hasAuthorship W4321368590A5015337971 @default.
• W4321368590 hasAuthorship W4321368590A5031311056 @default.
• W4321368590 hasAuthorship W4321368590A5033510051 @default.
• W4321368590 hasAuthorship W4321368590A5073973101 @default.
• W4321368590 hasConcept C103278499 @default.
• W4321368590 hasConcept C115961682 @default.
• W4321368590 hasConcept C124101348 @default.
• W4321368590 hasConcept C153180895 @default.
• W4321368590 hasConcept C154945302 @default.
• W4321368590 hasConcept C203519979 @default.
• W4321368590 hasConcept C2776517306 @default.
• W4321368590 hasConcept C2778112365 @default.
• W4321368590 hasConcept C41008148 @default.
• W4321368590 hasConcept C54355233 @default.
• W4321368590 hasConcept C70721500 @default.
• W4321368590 hasConcept C86803240 @default.
• W4321368590 hasConceptScore W4321368590C103278499 @default.
• W4321368590 hasConceptScore W4321368590C115961682 @default.
• W4321368590 hasConceptScore W4321368590C124101348 @default.
• W4321368590 hasConceptScore W4321368590C153180895 @default.
• W4321368590 hasConceptScore W4321368590C154945302 @default.
• W4321368590 hasConceptScore W4321368590C203519979 @default.
• W4321368590 hasConceptScore W4321368590C2776517306 @default.
• W4321368590 hasConceptScore W4321368590C2778112365 @default.
• W4321368590 hasConceptScore W4321368590C41008148 @default.
• W4321368590 hasConceptScore W4321368590C54355233 @default.
• W4321368590 hasConceptScore W4321368590C70721500 @default.
• W4321368590 hasConceptScore W4321368590C86803240 @default.
• W4321368590 hasLocation W43213685901 @default.
• W4321368590 hasLocation W43213685902 @default.
• W4321368590 hasOpenAccess W4321368590 @default.
• W4321368590 hasPrimaryLocation W43213685901 @default.
• W4321368590 hasRelatedWork W1992869332 @default.
• W4321368590 hasRelatedWork W2084099224 @default.
• W4321368590 hasRelatedWork W2122740583 @default.
• W4321368590 hasRelatedWork W2612383974 @default.

• next