Matches in SemOpenAlex for { <https://semopenalex.org/work/W4321371911> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W4321371911 endingPage "631" @default.
- W4321371911 startingPage "631" @default.
- W4321371911 abstract "Background: The characteristics and roles of microbes in the occurrence and development of pulmonary nodules are still unclear. Methods: We retrospectively analyzed the microbial mNGS results of BALF from 229 patients with pulmonary nodules before surgery, and performed a comparative analysis of lung flora between lung cancer and benign nodules according to postoperative pathology. The analysis also focused on investigating the characteristics of lung microbiota in lung adenocarcinomas with varying histopathology. Results: There were differences in lung microbiota between lung cancer and benign lung nodules. Bacterial diversity was lower in lung cancer than in benign lung nodules. Four species (Porphyromonas somerae, Corynebacterium accolens, Burkholderia cenocepacia and Streptococcus mitis) were enriched in lung cancer compared with the benign lung nodules. The areas under the ROC curves of these four species were all greater than 0.6, and the AUC of Streptococcus mitis was 0.702, which had the highest diagnostic value for differentiating lung cancer from benign lung diseases. The significantly enriched microbiota varied with the different pathological subtypes of lung adenocarcinoma. Streptococcus mitis, Burkholderia oklahomensis and Burkholderia latens displayed a trend of increasing from the benign lung disease group to the AIS group, MIA group and IAC group, whereas Lactobacillus plantarum showed a downward trend. Conclusion: Changes in the abundance of lung microbiota are closely related to the development of infiltrating adenocarcinoma. Our findings provide new insights into the relationship between the changes in lung microbiota and the development of lung cancer." @default.
- W4321371911 created "2023-02-21" @default.
- W4321371911 creator A5002520489 @default.
- W4321371911 creator A5014351098 @default.
- W4321371911 creator A5057601937 @default.
- W4321371911 creator A5062362866 @default.
- W4321371911 creator A5078870440 @default.
- W4321371911 creator A5078922412 @default.
- W4321371911 date "2023-02-20" @default.
- W4321371911 modified "2023-10-05" @default.
- W4321371911 title "A Preliminary Study on Microbiota Characteristics of Bronchoalveolar Lavage Fluid in Patients with Pulmonary Nodules Based on Metagenomic Next-Generation Sequencing" @default.
- W4321371911 cites W1757407923 @default.
- W4321371911 cites W1953677527 @default.
- W4321371911 cites W1974243960 @default.
- W4321371911 cites W1984646300 @default.
- W4321371911 cites W2100364589 @default.
- W4321371911 cites W2162888767 @default.
- W4321371911 cites W2307660471 @default.
- W4321371911 cites W2412662643 @default.
- W4321371911 cites W2535300095 @default.
- W4321371911 cites W2549034025 @default.
- W4321371911 cites W2617661002 @default.
- W4321371911 cites W2618692250 @default.
- W4321371911 cites W2765190797 @default.
- W4321371911 cites W2809030952 @default.
- W4321371911 cites W2903912375 @default.
- W4321371911 cites W2940328261 @default.
- W4321371911 cites W2952200067 @default.
- W4321371911 cites W2969632038 @default.
- W4321371911 cites W2971894732 @default.
- W4321371911 cites W2972665961 @default.
- W4321371911 cites W2992754107 @default.
- W4321371911 cites W2995075491 @default.
- W4321371911 cites W3017929917 @default.
- W4321371911 cites W3023401048 @default.
- W4321371911 cites W3029987075 @default.
- W4321371911 cites W3035845224 @default.
- W4321371911 cites W3080715822 @default.
- W4321371911 cites W3128646645 @default.
- W4321371911 cites W3138215020 @default.
- W4321371911 cites W3165728121 @default.
- W4321371911 cites W3173238759 @default.
- W4321371911 cites W4221056666 @default.
- W4321371911 cites W4280508459 @default.
- W4321371911 doi "https://doi.org/10.3390/biomedicines11020631" @default.
- W4321371911 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36831166" @default.
- W4321371911 hasPublicationYear "2023" @default.
- W4321371911 type Work @default.
- W4321371911 citedByCount "1" @default.
- W4321371911 countsByYear W43213719112023 @default.
- W4321371911 crossrefType "journal-article" @default.
- W4321371911 hasAuthorship W4321371911A5002520489 @default.
- W4321371911 hasAuthorship W4321371911A5014351098 @default.
- W4321371911 hasAuthorship W4321371911A5057601937 @default.
- W4321371911 hasAuthorship W4321371911A5062362866 @default.
- W4321371911 hasAuthorship W4321371911A5078870440 @default.
- W4321371911 hasAuthorship W4321371911A5078922412 @default.
- W4321371911 hasBestOaLocation W43213719111 @default.
- W4321371911 hasConcept C121608353 @default.
- W4321371911 hasConcept C126322002 @default.
- W4321371911 hasConcept C142724271 @default.
- W4321371911 hasConcept C2776256026 @default.
- W4321371911 hasConcept C2777714996 @default.
- W4321371911 hasConcept C2777961210 @default.
- W4321371911 hasConcept C2780698514 @default.
- W4321371911 hasConcept C2781182431 @default.
- W4321371911 hasConcept C71924100 @default.
- W4321371911 hasConcept C86803240 @default.
- W4321371911 hasConceptScore W4321371911C121608353 @default.
- W4321371911 hasConceptScore W4321371911C126322002 @default.
- W4321371911 hasConceptScore W4321371911C142724271 @default.
- W4321371911 hasConceptScore W4321371911C2776256026 @default.
- W4321371911 hasConceptScore W4321371911C2777714996 @default.
- W4321371911 hasConceptScore W4321371911C2777961210 @default.
- W4321371911 hasConceptScore W4321371911C2780698514 @default.
- W4321371911 hasConceptScore W4321371911C2781182431 @default.
- W4321371911 hasConceptScore W4321371911C71924100 @default.
- W4321371911 hasConceptScore W4321371911C86803240 @default.
- W4321371911 hasIssue "2" @default.
- W4321371911 hasLocation W43213719111 @default.
- W4321371911 hasLocation W43213719112 @default.
- W4321371911 hasLocation W43213719113 @default.
- W4321371911 hasOpenAccess W4321371911 @default.
- W4321371911 hasPrimaryLocation W43213719111 @default.
- W4321371911 hasRelatedWork W1969927172 @default.
- W4321371911 hasRelatedWork W2083312306 @default.
- W4321371911 hasRelatedWork W2338275154 @default.
- W4321371911 hasRelatedWork W2364779800 @default.
- W4321371911 hasRelatedWork W2377056512 @default.
- W4321371911 hasRelatedWork W2382060586 @default.
- W4321371911 hasRelatedWork W2515088231 @default.
- W4321371911 hasRelatedWork W2562771216 @default.
- W4321371911 hasRelatedWork W3093441533 @default.
- W4321371911 hasRelatedWork W1776799141 @default.
- W4321371911 hasVolume "11" @default.
- W4321371911 isParatext "false" @default.
- W4321371911 isRetracted "false" @default.
- W4321371911 workType "article" @default.