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- W4321372273 abstract "Background: Here, the inverse protein folding problem is approached from the viewpoint of the entropic index q. We present a brief overview of the problem. Further, we provide general information about the three-dimensional structure of proteins and the universal characteristics of the folding process. Methods: We explain how the stereochemical model was conceived. Our main objective is to change how Monte Carlo (MC) simulations are performed. We replace the Boltzmann weight with the Tsallis weight in order to achieve better sampling. This change leads to the q Monte Carlo method (MCq). There are two main ways to employ the index q: one is to set it as a fixed parameter (MCq*), and the other is to set it as an autonomous variable associated with the instantaneous molecular radius of gyration, a feature that is allowed by the Beck-Cohen superstatistics. In addition, we propose a meaningful physical interpretation for the index q. Furthermore, we explain how to assemble amino acid sequences for the inverse problem. Results: We present several results and discuss the implications associated with the MC and MCq methods. The latter method is an efficient approach to tracking down folding intermediate conformations, which can enable us to better find and define folding pathways for successive configurations of a polymeric chain kept in solution at the same macroscale temperature, T. Conclusion: We have explained how and why protein kinetics becomes significantly more advantageous when we employ q ≠ 1. However, this is only possible if we set the correct upper value of qmax." @default.
- W4321372273 created "2023-02-21" @default.
- W4321372273 creator A5041371232 @default.
- W4321372273 creator A5057974789 @default.
- W4321372273 creator A5072967843 @default.
- W4321372273 creator A5074731727 @default.
- W4321372273 creator A5080777965 @default.
- W4321372273 creator A5082940557 @default.
- W4321372273 date "2023-07-01" @default.
- W4321372273 modified "2023-09-26" @default.
- W4321372273 title "Roles of the Stereochemical Code and the Entropic Index q in the Protein Folding Process: How to Map Out Folding Intermediate Conformations" @default.
- W4321372273 cites W1531742640 @default.
- W4321372273 cites W1550166367 @default.
- W4321372273 cites W157808733 @default.
- W4321372273 cites W1973646362 @default.
- W4321372273 cites W1976627513 @default.
- W4321372273 cites W1976895959 @default.
- W4321372273 cites W1979754565 @default.
- W4321372273 cites W1980176289 @default.
- W4321372273 cites W1983874169 @default.
- W4321372273 cites W1992803403 @default.
- W4321372273 cites W1993281701 @default.
- W4321372273 cites W1995641408 @default.
- W4321372273 cites W1998354678 @default.
- W4321372273 cites W2004359919 @default.
- W4321372273 cites W2008862801 @default.
- W4321372273 cites W2011235285 @default.
- W4321372273 cites W2018340497 @default.
- W4321372273 cites W2027739701 @default.
- W4321372273 cites W2029753870 @default.
- W4321372273 cites W2030942911 @default.
- W4321372273 cites W2032168101 @default.
- W4321372273 cites W2032315737 @default.
- W4321372273 cites W2033491666 @default.
- W4321372273 cites W2035042310 @default.
- W4321372273 cites W2040390777 @default.
- W4321372273 cites W2041442662 @default.
- W4321372273 cites W2043068988 @default.
- W4321372273 cites W2045777307 @default.
- W4321372273 cites W2047115921 @default.
- W4321372273 cites W2049902088 @default.
- W4321372273 cites W2052745809 @default.
- W4321372273 cites W2055807766 @default.
- W4321372273 cites W2056499061 @default.
- W4321372273 cites W2056633203 @default.
- W4321372273 cites W2056760934 @default.
- W4321372273 cites W2057998277 @default.
- W4321372273 cites W2059356599 @default.
- W4321372273 cites W2061286817 @default.
- W4321372273 cites W2063157477 @default.
- W4321372273 cites W2063394267 @default.
- W4321372273 cites W2064277607 @default.
- W4321372273 cites W2069538595 @default.
- W4321372273 cites W2071827783 @default.
- W4321372273 cites W2075230856 @default.
- W4321372273 cites W2076758466 @default.
- W4321372273 cites W2079061079 @default.
- W4321372273 cites W2081465888 @default.
- W4321372273 cites W2081699341 @default.
- W4321372273 cites W2084771278 @default.
- W4321372273 cites W2085132749 @default.
- W4321372273 cites W2089597488 @default.
- W4321372273 cites W2089732998 @default.
- W4321372273 cites W2091585247 @default.
- W4321372273 cites W2092227167 @default.
- W4321372273 cites W2093245942 @default.
- W4321372273 cites W2097144976 @default.
- W4321372273 cites W2097793964 @default.
- W4321372273 cites W2099804970 @default.
- W4321372273 cites W2114899912 @default.
- W4321372273 cites W2115824900 @default.
- W4321372273 cites W2119619424 @default.
- W4321372273 cites W2122879224 @default.
- W4321372273 cites W2129020329 @default.
- W4321372273 cites W2135376694 @default.
- W4321372273 cites W2135857591 @default.
- W4321372273 cites W2160721947 @default.
- W4321372273 cites W2164056206 @default.
- W4321372273 cites W2165070060 @default.
- W4321372273 cites W2171755502 @default.
- W4321372273 cites W2227691753 @default.
- W4321372273 cites W2328718417 @default.
- W4321372273 cites W2476555123 @default.
- W4321372273 cites W2505710352 @default.
- W4321372273 cites W2516988692 @default.
- W4321372273 cites W2616482252 @default.
- W4321372273 cites W2621171941 @default.
- W4321372273 cites W2765096925 @default.
- W4321372273 cites W2766213780 @default.
- W4321372273 cites W2786288410 @default.
- W4321372273 cites W2809682566 @default.
- W4321372273 cites W2905098961 @default.
- W4321372273 cites W3004537654 @default.
- W4321372273 cites W3099318641 @default.
- W4321372273 cites W3105804567 @default.
- W4321372273 cites W3179412555 @default.
- W4321372273 cites W4210446570 @default.
- W4321372273 cites W4231687540 @default.