Matches in SemOpenAlex for { <https://semopenalex.org/work/W4321372471> ?p ?o ?g. }
- W4321372471 endingPage "516" @default.
- W4321372471 startingPage "516" @default.
- W4321372471 abstract "Cardiac hepatopathy refers to acute or chronic liver damage caused by cardiac dysfunction in the absence of any other possible causative reasons of liver injury. There is a large number of evidence of the fact that cardiac hepatopathy is associated with poor clinical outcomes in patients with acute or actually decompensated heart failure (HF). However, the currently dominated pathophysiological background does not explain a role of metabolic regulative proteins secreted by hepatocytes in progression of HF, including adverse cardiac remodeling, kidney injury, skeletal muscle dysfunction, osteopenia, sarcopenia and cardiac cachexia. The aim of this narrative review was to accumulate knowledge of hepatokines (adropin; fetuin-A, selenoprotein P, fibroblast growth factor-21, and alpha-1-microglobulin) as adaptive regulators of metabolic homeostasis in patients with HF. It is suggested that hepatokines play a crucial, causative role in inter-organ interactions and mediate tissue protective effects counteracting oxidative stress, inflammation, mitochondrial dysfunction, apoptosis and necrosis. The discriminative potencies of hepatokines for HF and damage of target organs in patients with known HF is under on-going scientific discussion and requires more investigations in the future." @default.
- W4321372471 created "2023-02-21" @default.
- W4321372471 creator A5020320881 @default.
- W4321372471 creator A5021590363 @default.
- W4321372471 creator A5069901543 @default.
- W4321372471 creator A5072768076 @default.
- W4321372471 creator A5076609618 @default.
- W4321372471 creator A5081468588 @default.
- W4321372471 date "2023-02-17" @default.
- W4321372471 modified "2023-10-05" @default.
- W4321372471 title "Cardiac Hepatopathy: New Perspectives on Old Problems through a Prism of Endogenous Metabolic Regulations by Hepatokines" @default.
- W4321372471 cites W1424960567 @default.
- W4321372471 cites W1553933086 @default.
- W4321372471 cites W1562174550 @default.
- W4321372471 cites W1753999167 @default.
- W4321372471 cites W1936992221 @default.
- W4321372471 cites W1965996356 @default.
- W4321372471 cites W1966826140 @default.
- W4321372471 cites W1970136916 @default.
- W4321372471 cites W1971082641 @default.
- W4321372471 cites W1973697736 @default.
- W4321372471 cites W1975525313 @default.
- W4321372471 cites W1976113377 @default.
- W4321372471 cites W1978110073 @default.
- W4321372471 cites W1978868043 @default.
- W4321372471 cites W1981497869 @default.
- W4321372471 cites W1981781254 @default.
- W4321372471 cites W1984412077 @default.
- W4321372471 cites W1985480663 @default.
- W4321372471 cites W1990034749 @default.
- W4321372471 cites W1993331859 @default.
- W4321372471 cites W1996017311 @default.
- W4321372471 cites W1997667793 @default.
- W4321372471 cites W1998748239 @default.
- W4321372471 cites W2004936358 @default.
- W4321372471 cites W2008238942 @default.
- W4321372471 cites W2009705743 @default.
- W4321372471 cites W2011826749 @default.
- W4321372471 cites W2012744420 @default.
- W4321372471 cites W2016374074 @default.
- W4321372471 cites W2022635485 @default.
- W4321372471 cites W2022790785 @default.
- W4321372471 cites W2028052759 @default.
- W4321372471 cites W2032614605 @default.
- W4321372471 cites W2033294617 @default.
- W4321372471 cites W2034339583 @default.
- W4321372471 cites W2039868172 @default.
- W4321372471 cites W2042218821 @default.
- W4321372471 cites W2044025620 @default.
- W4321372471 cites W2050240400 @default.
- W4321372471 cites W2051696948 @default.
- W4321372471 cites W2052356187 @default.
- W4321372471 cites W2052953200 @default.
- W4321372471 cites W2061971880 @default.
- W4321372471 cites W2071935077 @default.
- W4321372471 cites W2072478284 @default.
- W4321372471 cites W2076430953 @default.
- W4321372471 cites W2076550637 @default.
- W4321372471 cites W2081438731 @default.
- W4321372471 cites W2086087714 @default.
- W4321372471 cites W2088503595 @default.
- W4321372471 cites W2091878182 @default.
- W4321372471 cites W2092839850 @default.
- W4321372471 cites W2092934024 @default.
- W4321372471 cites W2099629184 @default.
- W4321372471 cites W2100232436 @default.
- W4321372471 cites W2128953247 @default.
- W4321372471 cites W2132596222 @default.
- W4321372471 cites W2132804815 @default.
- W4321372471 cites W2133948398 @default.
- W4321372471 cites W2137592087 @default.
- W4321372471 cites W2147361399 @default.
- W4321372471 cites W2152760193 @default.
- W4321372471 cites W2155391879 @default.
- W4321372471 cites W2157521845 @default.
- W4321372471 cites W2158301788 @default.
- W4321372471 cites W2158501840 @default.
- W4321372471 cites W2160615487 @default.
- W4321372471 cites W2162517996 @default.
- W4321372471 cites W2172687959 @default.
- W4321372471 cites W2194536288 @default.
- W4321372471 cites W2195520254 @default.
- W4321372471 cites W2209888725 @default.
- W4321372471 cites W2217502460 @default.
- W4321372471 cites W2227482793 @default.
- W4321372471 cites W2294945370 @default.
- W4321372471 cites W2297563106 @default.
- W4321372471 cites W2344984541 @default.
- W4321372471 cites W2387832857 @default.
- W4321372471 cites W2406957010 @default.
- W4321372471 cites W2408162146 @default.
- W4321372471 cites W2409224011 @default.
- W4321372471 cites W2411917180 @default.
- W4321372471 cites W2418773540 @default.
- W4321372471 cites W2423645096 @default.
- W4321372471 cites W2462467819 @default.
- W4321372471 cites W2464693207 @default.
- W4321372471 cites W2468882467 @default.