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- W4321381959 startingPage "102279" @default.
- W4321381959 abstract "Most bacteria are surrounded by a cell wall composed of peptidoglycan (PG) that specifies shape and protects the cell from osmotic rupture. Growth, division, and morphogenesis are intimately linked to the synthesis of this exoskeleton but also its hydrolysis. The enzymes that cleave the PG meshwork require careful control to prevent aberrant hydrolysis and loss of envelope integrity. Bacteria employ diverse mechanisms to control the activity, localization, and abundance of these potentially autolytic enzymes. Here, we discuss four examples of how cells integrate these control mechanisms to finely tune cell wall hydrolysis. We highlight recent advances and exciting avenues for future investigation." @default.
- W4321381959 created "2023-02-21" @default.
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- W4321381959 date "2023-04-01" @default.
- W4321381959 modified "2023-10-17" @default.
- W4321381959 title "Regulation of peptidoglycan hydrolases: localization, abundance, and activity" @default.
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- W4321381959 doi "https://doi.org/10.1016/j.mib.2023.102279" @default.
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