FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4321429270> ?p ?o ?g. }

• W4321429270 endingPage "124" @default.
• W4321429270 startingPage "116" @default.
• W4321429270 abstract "Prostate cancer (PCa) is the second most prevalent oncologic disease among men worldwide. Expression of various transcripts, including miRNAs, is markedly deregulated in cancerous prostate tissue. This study aimed at identifying a PCa-specific expression profile of miRNAs for subsequent use in noninvasive diagnostics. MiRNA expression was profiled in 13 PCa tissues using human miRNA microarrays. Highly expressed miRNAs were selected for the analysis in urine of patients with PCa (N = 143) and benign prostate hyperplasia (BPH; N = 23) by means of real time PCR, while miRNAs showing the expression differences in relation to clinical variables were further analyzed in 52 PCa and 12 noncancerous prostate tissues (NPT) on TaqMan Low Density Arrays (TLDA). Analysis of miRNA expression in prostate tissue linked miR-95 to aggressive form of PCa. This miRNA was up-regulated in high grade (P = 0.041), the TMPRSS2-ERG fusion-positive tumors (P = 0.026), and in patients with subsequently developed biochemical recurrence (BCR; P = 0.054) after radical prostatectomy. MiRNAs highly expressed in PCa tissues were also detectable in urine from PCa patients. Moreover, the urinary levels of miR-21 had significant discriminatory power (P = 0.010) to separate PCa patients from BPH, while the combined analysis of urinary miR-19a and miR-19b was prognostic for BCR. In PCa, the diagnostic potential of urinary miRNA panel (miR-21, miR-19a, and miR-19b) was higher than that of the PSA test (AUC = 0.738 vs. AUC = 0.514). Measurement of urinary levels of PCa-specific miRNAs could assist in more specific detection of PCa and prediction of BCR." @default.
• W4321429270 created "2023-02-22" @default.
• W4321429270 creator A5011621315 @default.
• W4321429270 creator A5043703843 @default.
• W4321429270 creator A5047016945 @default.
• W4321429270 creator A5085485237 @default.
• W4321429270 date "2016-01-01" @default.
• W4321429270 modified "2023-10-16" @default.
• W4321429270 title "Detection of miRNAs in urine of prostate cancer patients" @default.
• W4321429270 cites W1549382495 @default.
• W4321429270 cites W1835240468 @default.
• W4321429270 cites W1907267245 @default.
• W4321429270 cites W1963800590 @default.
• W4321429270 cites W1964453634 @default.
• W4321429270 cites W1966434915 @default.
• W4321429270 cites W1968107667 @default.
• W4321429270 cites W1969270395 @default.
• W4321429270 cites W1970556917 @default.
• W4321429270 cites W1980068439 @default.
• W4321429270 cites W1985663400 @default.
• W4321429270 cites W1999360191 @default.
• W4321429270 cites W2004339436 @default.
• W4321429270 cites W2011789480 @default.
• W4321429270 cites W2013739627 @default.
• W4321429270 cites W2030331235 @default.
• W4321429270 cites W2033230987 @default.
• W4321429270 cites W2037715998 @default.
• W4321429270 cites W2041161374 @default.
• W4321429270 cites W2046409229 @default.
• W4321429270 cites W2049295538 @default.
• W4321429270 cites W2049658618 @default.
• W4321429270 cites W2067402229 @default.
• W4321429270 cites W2072794530 @default.
• W4321429270 cites W2074908827 @default.
• W4321429270 cites W2094077020 @default.
• W4321429270 cites W2097325727 @default.
• W4321429270 cites W2118030557 @default.
• W4321429270 cites W2139834510 @default.
• W4321429270 cites W2139966272 @default.
• W4321429270 cites W2142448275 @default.
• W4321429270 cites W2150623996 @default.
• W4321429270 cites W2158636015 @default.
• W4321429270 cites W2162168304 @default.
• W4321429270 cites W2163025807 @default.
• W4321429270 cites W2167430092 @default.
• W4321429270 cites W2169375484 @default.
• W4321429270 cites W2169428763 @default.
• W4321429270 cites W40180828 @default.
• W4321429270 doi "https://doi.org/10.1016/j.medici.2016.02.007" @default.
• W4321429270 hasPublicationYear "2016" @default.
• W4321429270 type Work @default.
• W4321429270 citedByCount "48" @default.
• W4321429270 countsByYear W43214292702016 @default.
• W4321429270 countsByYear W43214292702017 @default.
• W4321429270 countsByYear W43214292702018 @default.
• W4321429270 countsByYear W43214292702019 @default.
• W4321429270 countsByYear W43214292702020 @default.
• W4321429270 countsByYear W43214292702021 @default.
• W4321429270 countsByYear W43214292702022 @default.
• W4321429270 countsByYear W43214292702023 @default.
• W4321429270 crossrefType "journal-article" @default.
• W4321429270 hasAuthorship W4321429270A5011621315 @default.
• W4321429270 hasAuthorship W4321429270A5043703843 @default.
• W4321429270 hasAuthorship W4321429270A5047016945 @default.
• W4321429270 hasAuthorship W4321429270A5085485237 @default.
• W4321429270 hasBestOaLocation W43214292701 @default.
• W4321429270 hasConcept C104317684 @default.
• W4321429270 hasConcept C121608353 @default.
• W4321429270 hasConcept C126322002 @default.
• W4321429270 hasConcept C143998085 @default.
• W4321429270 hasConcept C145059251 @default.
• W4321429270 hasConcept C2776235491 @default.
• W4321429270 hasConcept C2777562237 @default.
• W4321429270 hasConcept C2778042024 @default.
• W4321429270 hasConcept C2779134260 @default.
• W4321429270 hasConcept C2779466945 @default.
• W4321429270 hasConcept C2780192828 @default.
• W4321429270 hasConcept C3008058167 @default.
• W4321429270 hasConcept C524204448 @default.
• W4321429270 hasConcept C54355233 @default.
• W4321429270 hasConcept C71924100 @default.
• W4321429270 hasConcept C77411442 @default.
• W4321429270 hasConcept C86803240 @default.
• W4321429270 hasConcept C87874733 @default.
• W4321429270 hasConceptScore W4321429270C104317684 @default.
• W4321429270 hasConceptScore W4321429270C121608353 @default.
• W4321429270 hasConceptScore W4321429270C126322002 @default.
• W4321429270 hasConceptScore W4321429270C143998085 @default.
• W4321429270 hasConceptScore W4321429270C145059251 @default.
• W4321429270 hasConceptScore W4321429270C2776235491 @default.
• W4321429270 hasConceptScore W4321429270C2777562237 @default.
• W4321429270 hasConceptScore W4321429270C2778042024 @default.
• W4321429270 hasConceptScore W4321429270C2779134260 @default.
• W4321429270 hasConceptScore W4321429270C2779466945 @default.
• W4321429270 hasConceptScore W4321429270C2780192828 @default.
• W4321429270 hasConceptScore W4321429270C3008058167 @default.
• W4321429270 hasConceptScore W4321429270C524204448 @default.
• W4321429270 hasConceptScore W4321429270C54355233 @default.

• next