FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4321438410> ?p ?o ?g. }

• W4321438410 endingPage "488" @default.
• W4321438410 startingPage "477" @default.
• W4321438410 abstract "The pandemic subsequent to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus resulted, for the French institutional pharmacovigilance, in a health crisis in 2 phases: the coronavirus disease 2019 - COVID-19 phase during which the missions of the Regional Pharmacovigilance Centres (RPVC) were to detect a possible impact of drugs on this disease, as whether existed a possible aggravating role of certain drugs, or the safety profile of drugs used for the management of COVID-19 could evolve. The second phase followed the availability of COVID-19 vaccines, during which the RPVCs' missions were to detect as early as possible any new serious adverse effect, source of a potential signal that would modify the benefit/risk ratio of a vaccine and require the implementation of health safety measures. During these two periods, signal detection remained the core business of the RPVCs. The RPVCs had to organize themselves to handle an historical surge of declarations and requests for advice, whereas the RPVCs in charge of monitoring vaccines had to deal with an extraordinary dense activity over a long period of time, in order to produce in real time and on a weekly basis, a summary of all the declarations and an analysis of safety signals. The national organization put in place made it possible to meet the challenge of real-time pharmacovigilance monitoring of 4 vaccines with conditional marketing authorizations. Short-circuit efficient exchanges with the French Regional Pharmacovigilance Centres Network was paramount for the French National Agency for medicines and health products (Agence nationale de sécurité du médicament et des produits de santé) to develop an optimal collaborative partnership. The RPVC network has shown agility and flexibility, has been able to adapt swiftly and demonstrated its effectiveness in the early detection of safety signals. This crisis confirmed the superiority of manual/human signal detection as the most effective and powerful tool to date, to rapidly detect a new adverse drug reaction and enable to elaborate rapid measures of risk reduction. In order to maintain the performance of French RPVCs in signal detection and to monitor all drugs as they should and as expected by our fellow citizens, a new funding model correcting the inadequacy of RPVCs' expertise resources in relation to the volume of reports should be considered." @default.
• W4321438410 created "2023-02-22" @default.
• W4321438410 creator A5016176687 @default.
• W4321438410 creator A5017322608 @default.
• W4321438410 creator A5040566637 @default.
• W4321438410 creator A5041668518 @default.
• W4321438410 creator A5046970380 @default.
• W4321438410 creator A5065871425 @default.
• W4321438410 creator A5083754996 @default.
• W4321438410 date "2023-09-01" @default.
• W4321438410 modified "2023-10-14" @default.
• W4321438410 title "Pharmacovigilance des médicaments et des vaccins contre la COVID-19 durant la pandémie : comment le Réseau français des centres régionaux de pharmacovigilance a relevé le défi ?" @default.
• W4321438410 cites W3014784601 @default.
• W4321438410 cites W3021000736 @default.
• W4321438410 cites W3021161969 @default.
• W4321438410 cites W3025085572 @default.
• W4321438410 cites W3026991244 @default.
• W4321438410 cites W3036048791 @default.
• W4321438410 cites W3086538882 @default.
• W4321438410 cites W3116131148 @default.
• W4321438410 cites W3158285812 @default.
• W4321438410 cites W3160575855 @default.
• W4321438410 cites W3170842464 @default.
• W4321438410 cites W4200076071 @default.
• W4321438410 cites W4214886695 @default.
• W4321438410 cites W4283514019 @default.
• W4321438410 cites W4297914147 @default.
• W4321438410 cites W4321116962 @default.
• W4321438410 doi "https://doi.org/10.1016/j.therap.2023.02.009" @default.
• W4321438410 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36890032" @default.
• W4321438410 hasPublicationYear "2023" @default.
• W4321438410 type Work @default.
• W4321438410 citedByCount "1" @default.
• W4321438410 countsByYear W43214384102023 @default.
• W4321438410 crossrefType "journal-article" @default.
• W4321438410 hasAuthorship W4321438410A5016176687 @default.
• W4321438410 hasAuthorship W4321438410A5017322608 @default.
• W4321438410 hasAuthorship W4321438410A5040566637 @default.
• W4321438410 hasAuthorship W4321438410A5041668518 @default.
• W4321438410 hasAuthorship W4321438410A5046970380 @default.
• W4321438410 hasAuthorship W4321438410A5065871425 @default.
• W4321438410 hasAuthorship W4321438410A5083754996 @default.
• W4321438410 hasBestOaLocation W43214384102 @default.
• W4321438410 hasConcept C108170787 @default.
• W4321438410 hasConcept C111472728 @default.
• W4321438410 hasConcept C138885662 @default.
• W4321438410 hasConcept C142724271 @default.
• W4321438410 hasConcept C147483822 @default.
• W4321438410 hasConcept C197934379 @default.
• W4321438410 hasConcept C203014093 @default.
• W4321438410 hasConcept C2777589142 @default.
• W4321438410 hasConcept C2779134260 @default.
• W4321438410 hasConcept C2780801004 @default.
• W4321438410 hasConcept C3008058167 @default.
• W4321438410 hasConcept C3019706980 @default.
• W4321438410 hasConcept C524204448 @default.
• W4321438410 hasConcept C545542383 @default.
• W4321438410 hasConcept C57658597 @default.
• W4321438410 hasConcept C60644358 @default.
• W4321438410 hasConcept C71924100 @default.
• W4321438410 hasConcept C86803240 @default.
• W4321438410 hasConcept C89623803 @default.
• W4321438410 hasConcept C98274493 @default.
• W4321438410 hasConceptScore W4321438410C108170787 @default.
• W4321438410 hasConceptScore W4321438410C111472728 @default.
• W4321438410 hasConceptScore W4321438410C138885662 @default.
• W4321438410 hasConceptScore W4321438410C142724271 @default.
• W4321438410 hasConceptScore W4321438410C147483822 @default.
• W4321438410 hasConceptScore W4321438410C197934379 @default.
• W4321438410 hasConceptScore W4321438410C203014093 @default.
• W4321438410 hasConceptScore W4321438410C2777589142 @default.
• W4321438410 hasConceptScore W4321438410C2779134260 @default.
• W4321438410 hasConceptScore W4321438410C2780801004 @default.
• W4321438410 hasConceptScore W4321438410C3008058167 @default.
• W4321438410 hasConceptScore W4321438410C3019706980 @default.
• W4321438410 hasConceptScore W4321438410C524204448 @default.
• W4321438410 hasConceptScore W4321438410C545542383 @default.
• W4321438410 hasConceptScore W4321438410C57658597 @default.
• W4321438410 hasConceptScore W4321438410C60644358 @default.
• W4321438410 hasConceptScore W4321438410C71924100 @default.
• W4321438410 hasConceptScore W4321438410C86803240 @default.
• W4321438410 hasConceptScore W4321438410C89623803 @default.
• W4321438410 hasConceptScore W4321438410C98274493 @default.
• W4321438410 hasIssue "5" @default.
• W4321438410 hasLocation W43214384101 @default.
• W4321438410 hasLocation W43214384102 @default.
• W4321438410 hasLocation W43214384103 @default.
• W4321438410 hasOpenAccess W4321438410 @default.
• W4321438410 hasPrimaryLocation W43214384101 @default.
• W4321438410 hasRelatedWork W1965742035 @default.
• W4321438410 hasRelatedWork W2014008304 @default.
• W4321438410 hasRelatedWork W2052372237 @default.
• W4321438410 hasRelatedWork W2418870033 @default.
• W4321438410 hasRelatedWork W2479055662 @default.
• W4321438410 hasRelatedWork W2528993925 @default.
• W4321438410 hasRelatedWork W2593997683 @default.
• W4321438410 hasRelatedWork W2950708040 @default.
• W4321438410 hasRelatedWork W3112509942 @default.

• next