Matches in SemOpenAlex for { <https://semopenalex.org/work/W4321441457> ?p ?o ?g. }
- W4321441457 endingPage "1033" @default.
- W4321441457 startingPage "1023" @default.
- W4321441457 abstract "Biomolecules forming membraneless structures via liquid-liquid phase separation (LLPS) is a common event in living cells. Some liquid-like condensates can convert into solid-like aggregations, and such a phase transition process is related to some neurodegenerative diseases. Liquid-like condensates and solid-like aggregations usually exhibit distinctive fluidity and are commonly distinguished via their morphology and dynamic properties identified through ensemble methods. Emerging single-molecule techniques are a group of highly sensitive techniques, which can offer further mechanistic insights into LLPS and phase transition at the molecular level. Here, we summarize the working principles of several commonly used single-molecule techniques and demonstrate their unique power in manipulating LLPS, examining mechanical properties at the nanoscale, and monitoring dynamic and thermodynamic properties at the molecular level. Thus, single-molecule techniques are unique tools to characterize LLPS and liquid-to-solid phase transition under close-to-physiological conditions." @default.
- W4321441457 created "2023-02-22" @default.
- W4321441457 creator A5043363158 @default.
- W4321441457 creator A5046732096 @default.
- W4321441457 creator A5063926315 @default.
- W4321441457 date "2023-03-03" @default.
- W4321441457 modified "2023-09-25" @default.
- W4321441457 title "Single-molecule techniques to visualize and to characterize liquid-liquid phase separation and phase transition" @default.
- W4321441457 cites W1511517753 @default.
- W4321441457 cites W1611407165 @default.
- W4321441457 cites W1854281301 @default.
- W4321441457 cites W1894813487 @default.
- W4321441457 cites W1952608303 @default.
- W4321441457 cites W1965286266 @default.
- W4321441457 cites W1971463889 @default.
- W4321441457 cites W1986490461 @default.
- W4321441457 cites W1995636525 @default.
- W4321441457 cites W2000057317 @default.
- W4321441457 cites W2003618511 @default.
- W4321441457 cites W2008264883 @default.
- W4321441457 cites W2011011528 @default.
- W4321441457 cites W2020159880 @default.
- W4321441457 cites W2026226960 @default.
- W4321441457 cites W2038197478 @default.
- W4321441457 cites W2041451000 @default.
- W4321441457 cites W2050719403 @default.
- W4321441457 cites W2054352933 @default.
- W4321441457 cites W2059431762 @default.
- W4321441457 cites W2080880751 @default.
- W4321441457 cites W2082429191 @default.
- W4321441457 cites W2093373643 @default.
- W4321441457 cites W2103635033 @default.
- W4321441457 cites W2111796925 @default.
- W4321441457 cites W2113372755 @default.
- W4321441457 cites W2116382310 @default.
- W4321441457 cites W2119288587 @default.
- W4321441457 cites W2120156669 @default.
- W4321441457 cites W2135607950 @default.
- W4321441457 cites W2136290525 @default.
- W4321441457 cites W2140405694 @default.
- W4321441457 cites W2150860983 @default.
- W4321441457 cites W2168958678 @default.
- W4321441457 cites W2255386862 @default.
- W4321441457 cites W2267788562 @default.
- W4321441457 cites W2372745612 @default.
- W4321441457 cites W2514004327 @default.
- W4321441457 cites W2594130445 @default.
- W4321441457 cites W2713865210 @default.
- W4321441457 cites W2722642526 @default.
- W4321441457 cites W2728447527 @default.
- W4321441457 cites W2788827529 @default.
- W4321441457 cites W2790446628 @default.
- W4321441457 cites W2793180732 @default.
- W4321441457 cites W2797600975 @default.
- W4321441457 cites W2802667264 @default.
- W4321441457 cites W2803875145 @default.
- W4321441457 cites W2808847099 @default.
- W4321441457 cites W2884750823 @default.
- W4321441457 cites W2894620275 @default.
- W4321441457 cites W2895091861 @default.
- W4321441457 cites W2901765635 @default.
- W4321441457 cites W2907972520 @default.
- W4321441457 cites W2909378020 @default.
- W4321441457 cites W2911694576 @default.
- W4321441457 cites W2914098160 @default.
- W4321441457 cites W2916646997 @default.
- W4321441457 cites W2943495088 @default.
- W4321441457 cites W2943959526 @default.
- W4321441457 cites W2955360866 @default.
- W4321441457 cites W2966567728 @default.
- W4321441457 cites W2980998087 @default.
- W4321441457 cites W2988915271 @default.
- W4321441457 cites W2997658147 @default.
- W4321441457 cites W3036811605 @default.
- W4321441457 cites W3043339164 @default.
- W4321441457 cites W3049563515 @default.
- W4321441457 cites W3093057625 @default.
- W4321441457 cites W3094499969 @default.
- W4321441457 cites W3096801472 @default.
- W4321441457 cites W3109198778 @default.
- W4321441457 cites W3117859015 @default.
- W4321441457 cites W3120920966 @default.
- W4321441457 cites W3135396596 @default.
- W4321441457 cites W3135639803 @default.
- W4321441457 cites W3150768399 @default.
- W4321441457 cites W3161509742 @default.
- W4321441457 cites W3162292936 @default.
- W4321441457 cites W3191624148 @default.
- W4321441457 cites W3196238842 @default.
- W4321441457 cites W4210520048 @default.
- W4321441457 cites W4214514738 @default.
- W4321441457 cites W4220748037 @default.
- W4321441457 cites W4220921879 @default.
- W4321441457 cites W4221088553 @default.
- W4321441457 cites W4225138787 @default.
- W4321441457 cites W4225284472 @default.
- W4321441457 cites W4281943433 @default.
- W4321441457 cites W4284964379 @default.