FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4321487374> ?p ?o ?g. }

• W4321487374 endingPage "113686" @default.
• W4321487374 startingPage "113686" @default.
• W4321487374 abstract "This study investigated the potential lipid inhibitory and anti-obesity effects of compounds derived from Sargassum thunbergii in vitro and in vivo. We prepared a Celluclast-assisted hydrolysate from Sargassum thunbergii (STC) and three fractional ethanol precipitates (STCF1, STCF2, STCF3). We investigated their proximate composition, and anti-obesity effects in vitro and in vivo. STC and STCFs all significantly reduced intracellular lipid accumulation in PA-treated 3T3-L1 and HepG2 cells. STC, STCF1, and STCF3 had profound anti-obesity effects on high fat diet (HFD)-fed obesity model mice. Oral administration of STC, STCF1, and STCF3 significantly reduced body weight and white adipose tissue (WAT) mass. Furthermore, serum lipid levels were significantly decreased. Additionally, adipose specific hormone levels (adiponectin and fibroblast growth factor-21 (FGF-21)) were significantly decreased, and serum insulin levels were also decreased by STC, STCF1, and STCF3 treatment. A mechanistic study revealed that the adipogenesis and lipolysis associated proteins in epididymal adipose tissue, and free fatty acid oxidation in liver tissues were effectively regulated by STC, STCF1, and STCF3. Overall, our findings show the potent anti-obesity effects of STC, STCF1, and STCF3, achieved by regulation of adipogenesis, lipolysis, and the fatty acid oxidation pathway in HFD-treated obesity model mice." @default.
• W4321487374 created "2023-02-23" @default.
• W4321487374 creator A5009446618 @default.
• W4321487374 creator A5042689574 @default.
• W4321487374 creator A5070797383 @default.
• W4321487374 date "2023-04-01" @default.
• W4321487374 modified "2023-10-14" @default.
• W4321487374 title "Fucoidan from Sargassum thunbergii obtained via step gradient ethanol precipitation indicate potential anti-obesity and anti-hepatic steatosis in vitro 3T3-L1 and HepG2 cells and in vivo high-fat diet-induced obesity mice" @default.
• W4321487374 cites W1510986852 @default.
• W4321487374 cites W2015832516 @default.
• W4321487374 cites W2018226215 @default.
• W4321487374 cites W2031423487 @default.
• W4321487374 cites W2039252539 @default.
• W4321487374 cites W2048375374 @default.
• W4321487374 cites W2100232436 @default.
• W4321487374 cites W2122296266 @default.
• W4321487374 cites W2128925357 @default.
• W4321487374 cites W2159298950 @default.
• W4321487374 cites W2284659436 @default.
• W4321487374 cites W2508996693 @default.
• W4321487374 cites W2536504846 @default.
• W4321487374 cites W2743155225 @default.
• W4321487374 cites W2806274255 @default.
• W4321487374 cites W2903155258 @default.
• W4321487374 cites W2944549000 @default.
• W4321487374 cites W2994693763 @default.
• W4321487374 cites W3001984628 @default.
• W4321487374 cites W3046028838 @default.
• W4321487374 cites W3117083078 @default.
• W4321487374 cites W3129758593 @default.
• W4321487374 cites W3171144340 @default.
• W4321487374 cites W3187866843 @default.
• W4321487374 doi "https://doi.org/10.1016/j.fct.2023.113686" @default.
• W4321487374 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36828168" @default.
• W4321487374 hasPublicationYear "2023" @default.
• W4321487374 type Work @default.
• W4321487374 citedByCount "0" @default.
• W4321487374 crossrefType "journal-article" @default.
• W4321487374 hasAuthorship W4321487374A5009446618 @default.
• W4321487374 hasAuthorship W4321487374A5042689574 @default.
• W4321487374 hasAuthorship W4321487374A5070797383 @default.
• W4321487374 hasConcept C100817775 @default.
• W4321487374 hasConcept C122927707 @default.
• W4321487374 hasConcept C126322002 @default.
• W4321487374 hasConcept C134018914 @default.
• W4321487374 hasConcept C140985366 @default.
• W4321487374 hasConcept C150903083 @default.
• W4321487374 hasConcept C151955695 @default.
• W4321487374 hasConcept C171089720 @default.
• W4321487374 hasConcept C185592680 @default.
• W4321487374 hasConcept C207001950 @default.
• W4321487374 hasConcept C2775909754 @default.
• W4321487374 hasConcept C2776175330 @default.
• W4321487374 hasConcept C2776782570 @default.
• W4321487374 hasConcept C2777391703 @default.
• W4321487374 hasConcept C2778772119 @default.
• W4321487374 hasConcept C2779134260 @default.
• W4321487374 hasConcept C511355011 @default.
• W4321487374 hasConcept C543025807 @default.
• W4321487374 hasConcept C55493867 @default.
• W4321487374 hasConcept C71924100 @default.
• W4321487374 hasConcept C86803240 @default.
• W4321487374 hasConceptScore W4321487374C100817775 @default.
• W4321487374 hasConceptScore W4321487374C122927707 @default.
• W4321487374 hasConceptScore W4321487374C126322002 @default.
• W4321487374 hasConceptScore W4321487374C134018914 @default.
• W4321487374 hasConceptScore W4321487374C140985366 @default.
• W4321487374 hasConceptScore W4321487374C150903083 @default.
• W4321487374 hasConceptScore W4321487374C151955695 @default.
• W4321487374 hasConceptScore W4321487374C171089720 @default.
• W4321487374 hasConceptScore W4321487374C185592680 @default.
• W4321487374 hasConceptScore W4321487374C207001950 @default.
• W4321487374 hasConceptScore W4321487374C2775909754 @default.
• W4321487374 hasConceptScore W4321487374C2776175330 @default.
• W4321487374 hasConceptScore W4321487374C2776782570 @default.
• W4321487374 hasConceptScore W4321487374C2777391703 @default.
• W4321487374 hasConceptScore W4321487374C2778772119 @default.
• W4321487374 hasConceptScore W4321487374C2779134260 @default.
• W4321487374 hasConceptScore W4321487374C511355011 @default.
• W4321487374 hasConceptScore W4321487374C543025807 @default.
• W4321487374 hasConceptScore W4321487374C55493867 @default.
• W4321487374 hasConceptScore W4321487374C71924100 @default.
• W4321487374 hasConceptScore W4321487374C86803240 @default.
• W4321487374 hasFunder F4320321191 @default.
• W4321487374 hasFunder F4320322030 @default.
• W4321487374 hasFunder F4320334884 @default.
• W4321487374 hasLocation W43214873741 @default.
• W4321487374 hasLocation W43214873742 @default.
• W4321487374 hasOpenAccess W4321487374 @default.
• W4321487374 hasPrimaryLocation W43214873741 @default.
• W4321487374 hasRelatedWork W1964688190 @default.
• W4321487374 hasRelatedWork W1965568810 @default.
• W4321487374 hasRelatedWork W1979647427 @default.
• W4321487374 hasRelatedWork W2011657070 @default.
• W4321487374 hasRelatedWork W2018864477 @default.
• W4321487374 hasRelatedWork W2024340725 @default.
• W4321487374 hasRelatedWork W2078496896 @default.
• W4321487374 hasRelatedWork W2096961084 @default.

• next