Matches in SemOpenAlex for { <https://semopenalex.org/work/W4321495943> ?p ?o ?g. }
- W4321495943 endingPage "548" @default.
- W4321495943 startingPage "548" @default.
- W4321495943 abstract "Acute and chronic lung injuries are among the leading causes of mortality worldwide. Lung injury can affect several components of the respiratory system, including the airways, parenchyma, and pulmonary vasculature. Although acute and chronic lung injuries represent an enormous economic and clinical burden, currently available therapies primarily focus on alleviating disease symptoms rather than reversing and/or preventing lung pathology. Moreover, some supportive interventions, such as oxygen and mechanical ventilation, can lead to (further) deterioration of lung function and even the development of permanent injuries. Lastly, sepsis, which can originate extrapulmonary or in the respiratory system itself, contributes to many cases of lung-associated deaths. Considering these challenges, we aim to summarize molecular and cellular mechanisms, with a particular focus on airway inflammation and oxidative stress that lead to the characteristic pathophysiology of acute and chronic lung injuries. In addition, we will highlight the limitations of current therapeutic strategies and explore new antioxidant-based drug options that could potentially be effective in managing acute and chronic lung injuries." @default.
- W4321495943 created "2023-02-23" @default.
- W4321495943 creator A5001781113 @default.
- W4321495943 creator A5022694761 @default.
- W4321495943 creator A5024891732 @default.
- W4321495943 creator A5039996896 @default.
- W4321495943 creator A5055074801 @default.
- W4321495943 creator A5068313648 @default.
- W4321495943 creator A5069710505 @default.
- W4321495943 creator A5074634254 @default.
- W4321495943 creator A5084839392 @default.
- W4321495943 creator A5087210557 @default.
- W4321495943 date "2023-02-21" @default.
- W4321495943 modified "2023-10-11" @default.
- W4321495943 title "Oxidative Stress and Inflammation in Acute and Chronic Lung Injuries" @default.
- W4321495943 cites W1033557595 @default.
- W4321495943 cites W1070501797 @default.
- W4321495943 cites W1221909616 @default.
- W4321495943 cites W1489018618 @default.
- W4321495943 cites W1496071809 @default.
- W4321495943 cites W1498451757 @default.
- W4321495943 cites W1500755500 @default.
- W4321495943 cites W1520991027 @default.
- W4321495943 cites W1532516694 @default.
- W4321495943 cites W1575883964 @default.
- W4321495943 cites W1600560134 @default.
- W4321495943 cites W1605762737 @default.
- W4321495943 cites W1619279056 @default.
- W4321495943 cites W1652069479 @default.
- W4321495943 cites W1684699171 @default.
- W4321495943 cites W1755694215 @default.
- W4321495943 cites W1765643053 @default.
- W4321495943 cites W1782117688 @default.
- W4321495943 cites W1876456208 @default.
- W4321495943 cites W188223124 @default.
- W4321495943 cites W1903659344 @default.
- W4321495943 cites W1906540932 @default.
- W4321495943 cites W1924528760 @default.
- W4321495943 cites W1937294600 @default.
- W4321495943 cites W1937484011 @default.
- W4321495943 cites W1953978638 @default.
- W4321495943 cites W1954154166 @default.
- W4321495943 cites W1963639235 @default.
- W4321495943 cites W1964152652 @default.
- W4321495943 cites W1965285864 @default.
- W4321495943 cites W1965740485 @default.
- W4321495943 cites W1965811013 @default.
- W4321495943 cites W1966197639 @default.
- W4321495943 cites W1966672647 @default.
- W4321495943 cites W1966841153 @default.
- W4321495943 cites W1967664694 @default.
- W4321495943 cites W1969334234 @default.
- W4321495943 cites W1971090322 @default.
- W4321495943 cites W1972524560 @default.
- W4321495943 cites W1973081785 @default.
- W4321495943 cites W1973808559 @default.
- W4321495943 cites W1974367981 @default.
- W4321495943 cites W1974582664 @default.
- W4321495943 cites W1976929342 @default.
- W4321495943 cites W1977076292 @default.
- W4321495943 cites W1977127210 @default.
- W4321495943 cites W1978502718 @default.
- W4321495943 cites W1979317610 @default.
- W4321495943 cites W1979881414 @default.
- W4321495943 cites W1980429500 @default.
- W4321495943 cites W1980744863 @default.
- W4321495943 cites W1981907698 @default.
- W4321495943 cites W1982388830 @default.
- W4321495943 cites W1982997810 @default.
- W4321495943 cites W1983283608 @default.
- W4321495943 cites W1983751925 @default.
- W4321495943 cites W1984057139 @default.
- W4321495943 cites W1984454286 @default.
- W4321495943 cites W1984736526 @default.
- W4321495943 cites W1985241965 @default.
- W4321495943 cites W1986216062 @default.
- W4321495943 cites W1986704457 @default.
- W4321495943 cites W1986855761 @default.
- W4321495943 cites W1989121568 @default.
- W4321495943 cites W1990019821 @default.
- W4321495943 cites W1990077015 @default.
- W4321495943 cites W1994885986 @default.
- W4321495943 cites W1994996694 @default.
- W4321495943 cites W1995986855 @default.
- W4321495943 cites W1997745709 @default.
- W4321495943 cites W1998641419 @default.
- W4321495943 cites W1999233466 @default.
- W4321495943 cites W2000017694 @default.
- W4321495943 cites W2000204496 @default.
- W4321495943 cites W2000703640 @default.
- W4321495943 cites W2001470861 @default.
- W4321495943 cites W2004815940 @default.
- W4321495943 cites W2005143670 @default.
- W4321495943 cites W2006228166 @default.
- W4321495943 cites W2006572302 @default.
- W4321495943 cites W2008892946 @default.
- W4321495943 cites W2009382888 @default.
- W4321495943 cites W2009663184 @default.