Matches in SemOpenAlex for { <https://semopenalex.org/work/W4321509156> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W4321509156 endingPage "1020" @default.
- W4321509156 startingPage "1014" @default.
- W4321509156 abstract "Aim: In rural Gambia, birth season predicts infection-related adult mortality. Seasonal factors in early life may programme the immune system, possibly via an effect on thymic development. This study tested whether thymus size in rural Gambian infants is affected by birth season, defined as January-June (harvest, few infections) versus July-December (hungry, high infectious load). Methods: Thymic volume (thymic index) was assessed sonographically at 1, 8, 24 and 52 wk in 138 singleton infants born over 14 consecutive months. Growth and morbidity were regularly assessed. Results: Mean thymic index increased from 19.9 at 1 wk to 30.9 at 8 wk and 35.7 at 24 wk, then fell to 32.0 at 52 wk. Thymic index was associated with each preceding thymic index up to 24 wk. This tracking persisted after correcting for infant weight and month of measurement (p < 0.01). Thymic index at 1 wk was marginally but non-significantly lower in hungry season births (p= 0.06). Thymic index was lower in hungry season measurements; this effect persisted after adjusting for current weight and infection markers, and was strongest at 8 wk (p= 0.001). Conclusion: These results describe a pattern of thymic growth followed by diminution in size. An infant's thymic index tracks despite changes in body weight and season. Thymic index was lower in the hungry season. This appears not to be explained by infection or nutritional status. A possible influence of trophic factors in breast milk merits investigation." @default.
- W4321509156 created "2023-02-24" @default.
- W4321509156 creator A5017171403 @default.
- W4321509156 creator A5022905485 @default.
- W4321509156 creator A5033388213 @default.
- W4321509156 creator A5049359725 @default.
- W4321509156 date "2007-01-02" @default.
- W4321509156 modified "2023-10-12" @default.
- W4321509156 title "Birth season and environmental influences on patterns of thymic growth in rural Gambian infants" @default.
- W4321509156 cites W1503928854 @default.
- W4321509156 cites W1530140121 @default.
- W4321509156 cites W1979658153 @default.
- W4321509156 cites W1991583678 @default.
- W4321509156 cites W1998102826 @default.
- W4321509156 cites W2018118808 @default.
- W4321509156 cites W2030419068 @default.
- W4321509156 cites W2036972614 @default.
- W4321509156 cites W2044500936 @default.
- W4321509156 cites W2047975282 @default.
- W4321509156 cites W2048237871 @default.
- W4321509156 cites W2049099895 @default.
- W4321509156 cites W2065541632 @default.
- W4321509156 cites W2068756488 @default.
- W4321509156 cites W2075497738 @default.
- W4321509156 cites W2081737286 @default.
- W4321509156 cites W2090642065 @default.
- W4321509156 cites W2091802585 @default.
- W4321509156 cites W2100758038 @default.
- W4321509156 cites W2108224049 @default.
- W4321509156 cites W2124167765 @default.
- W4321509156 cites W2126364108 @default.
- W4321509156 cites W2128788606 @default.
- W4321509156 cites W2199417507 @default.
- W4321509156 cites W4245704439 @default.
- W4321509156 cites W2058412858 @default.
- W4321509156 doi "https://doi.org/10.1111/j.1651-2227.2003.tb02568.x" @default.
- W4321509156 hasPublicationYear "2007" @default.
- W4321509156 type Work @default.
- W4321509156 citedByCount "47" @default.
- W4321509156 countsByYear W43215091562012 @default.
- W4321509156 countsByYear W43215091562013 @default.
- W4321509156 countsByYear W43215091562014 @default.
- W4321509156 countsByYear W43215091562015 @default.
- W4321509156 countsByYear W43215091562017 @default.
- W4321509156 countsByYear W43215091562018 @default.
- W4321509156 countsByYear W43215091562019 @default.
- W4321509156 countsByYear W43215091562020 @default.
- W4321509156 countsByYear W43215091562021 @default.
- W4321509156 countsByYear W43215091562022 @default.
- W4321509156 countsByYear W43215091562023 @default.
- W4321509156 crossrefType "journal-article" @default.
- W4321509156 hasAuthorship W4321509156A5017171403 @default.
- W4321509156 hasAuthorship W4321509156A5022905485 @default.
- W4321509156 hasAuthorship W4321509156A5033388213 @default.
- W4321509156 hasAuthorship W4321509156A5049359725 @default.
- W4321509156 hasConcept C118552586 @default.
- W4321509156 hasConcept C2778299150 @default.
- W4321509156 hasConcept C2779234561 @default.
- W4321509156 hasConcept C42407357 @default.
- W4321509156 hasConcept C54355233 @default.
- W4321509156 hasConcept C66322754 @default.
- W4321509156 hasConcept C71924100 @default.
- W4321509156 hasConcept C86803240 @default.
- W4321509156 hasConceptScore W4321509156C118552586 @default.
- W4321509156 hasConceptScore W4321509156C2778299150 @default.
- W4321509156 hasConceptScore W4321509156C2779234561 @default.
- W4321509156 hasConceptScore W4321509156C42407357 @default.
- W4321509156 hasConceptScore W4321509156C54355233 @default.
- W4321509156 hasConceptScore W4321509156C66322754 @default.
- W4321509156 hasConceptScore W4321509156C71924100 @default.
- W4321509156 hasConceptScore W4321509156C86803240 @default.
- W4321509156 hasIssue "9" @default.
- W4321509156 hasLocation W43215091561 @default.
- W4321509156 hasOpenAccess W4321509156 @default.
- W4321509156 hasPrimaryLocation W43215091561 @default.
- W4321509156 hasRelatedWork W2168707082 @default.
- W4321509156 hasRelatedWork W2286481857 @default.
- W4321509156 hasRelatedWork W2389160714 @default.
- W4321509156 hasRelatedWork W2392320261 @default.
- W4321509156 hasRelatedWork W2616334581 @default.
- W4321509156 hasRelatedWork W2981832728 @default.
- W4321509156 hasRelatedWork W3030330557 @default.
- W4321509156 hasRelatedWork W4225728645 @default.
- W4321509156 hasRelatedWork W1776860882 @default.
- W4321509156 hasRelatedWork W2740253506 @default.
- W4321509156 hasVolume "92" @default.
- W4321509156 isParatext "false" @default.
- W4321509156 isRetracted "false" @default.
- W4321509156 workType "article" @default.