FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4321598770> ?p ?o ?g. }

• W4321598770 endingPage "4408" @default.
• W4321598770 startingPage "4408" @default.
• W4321598770 abstract "Diabetic retinopathy (DR) is a severe disease with a growing number of afflicted patients, which places a heavy burden on society, both socially and financially. While there are treatments available, they are not always effective and are usually administered when the disease is already at a developed stage with visible clinical manifestation. However, homeostasis at a molecular level is disrupted before visible signs of the disease are evident. Thus, there has been a constant search for effective biomarkers that could signal the onset of DR. There is evidence that early detection and prompt disease control are effective in preventing or slowing DR progression. Here, we review some of the molecular changes that occur before clinical manifestations are observable. As a possible new biomarker, we focus on retinol binding protein 3 (RBP3). We argue that it displays unique features that make it a very good biomarker for non-invasive, early-stage DR detection. Linking chemistry to biological function and focusing on new developments in eye imaging and two-photon technology, we describe a new potential diagnostic tool that would allow rapid and effective quantification of RBP3 in the retina. Moreover, this tool would also be useful in the future to monitor therapeutic effectiveness if levels of RBP3 are elevated by DR treatments." @default.
• W4321598770 created "2023-02-24" @default.
• W4321598770 creator A5004331487 @default.
• W4321598770 creator A5016672090 @default.
• W4321598770 creator A5044346958 @default.
• W4321598770 creator A5069968906 @default.
• W4321598770 date "2023-02-23" @default.
• W4321598770 modified "2023-09-26" @default.
• W4321598770 title "Towards a New Biomarker for Diabetic Retinopathy: Exploring RBP3 Structure and Retinoids Binding for Functional Imaging of Eyes In Vivo" @default.
• W4321598770 cites W100965007 @default.
• W4321598770 cites W1125525217 @default.
• W4321598770 cites W1491857460 @default.
• W4321598770 cites W1505348478 @default.
• W4321598770 cites W1517000564 @default.
• W4321598770 cites W1530037127 @default.
• W4321598770 cites W1530827369 @default.
• W4321598770 cites W1531998857 @default.
• W4321598770 cites W1539599110 @default.
• W4321598770 cites W1566249671 @default.
• W4321598770 cites W1576222260 @default.
• W4321598770 cites W1579846785 @default.
• W4321598770 cites W1581807191 @default.
• W4321598770 cites W1582931047 @default.
• W4321598770 cites W1589587808 @default.
• W4321598770 cites W160395879 @default.
• W4321598770 cites W1670731304 @default.
• W4321598770 cites W1748123995 @default.
• W4321598770 cites W1887888720 @default.
• W4321598770 cites W193667007 @default.
• W4321598770 cites W1953088627 @default.
• W4321598770 cites W1968352279 @default.
• W4321598770 cites W1968459833 @default.
• W4321598770 cites W1971792228 @default.
• W4321598770 cites W1972132166 @default.
• W4321598770 cites W1974247935 @default.
• W4321598770 cites W1977532673 @default.
• W4321598770 cites W1978668117 @default.
• W4321598770 cites W1985870422 @default.
• W4321598770 cites W1986623688 @default.
• W4321598770 cites W1986731294 @default.
• W4321598770 cites W1990083946 @default.
• W4321598770 cites W1992898823 @default.
• W4321598770 cites W1995045917 @default.
• W4321598770 cites W1995363602 @default.
• W4321598770 cites W1998614770 @default.
• W4321598770 cites W2002530587 @default.
• W4321598770 cites W2002617967 @default.
• W4321598770 cites W2003621204 @default.
• W4321598770 cites W2004937100 @default.
• W4321598770 cites W2005390270 @default.
• W4321598770 cites W2005767645 @default.
• W4321598770 cites W2006378422 @default.
• W4321598770 cites W2007031588 @default.
• W4321598770 cites W2007812010 @default.
• W4321598770 cites W2011158839 @default.
• W4321598770 cites W2011204895 @default.
• W4321598770 cites W2011947099 @default.
• W4321598770 cites W2013058529 @default.
• W4321598770 cites W2017629171 @default.
• W4321598770 cites W2021122140 @default.
• W4321598770 cites W2022992728 @default.
• W4321598770 cites W2023112559 @default.
• W4321598770 cites W2025213053 @default.
• W4321598770 cites W2027597866 @default.
• W4321598770 cites W2029444619 @default.
• W4321598770 cites W2035334171 @default.
• W4321598770 cites W2036663456 @default.
• W4321598770 cites W2040087338 @default.
• W4321598770 cites W2043463860 @default.
• W4321598770 cites W2044437167 @default.
• W4321598770 cites W2044721940 @default.
• W4321598770 cites W2046200610 @default.
• W4321598770 cites W2046919544 @default.
• W4321598770 cites W2046951190 @default.
• W4321598770 cites W2047508855 @default.
• W4321598770 cites W2051156128 @default.
• W4321598770 cites W2052529618 @default.
• W4321598770 cites W2054326088 @default.
• W4321598770 cites W2054862233 @default.
• W4321598770 cites W2055499485 @default.
• W4321598770 cites W2056796149 @default.
• W4321598770 cites W2057093539 @default.
• W4321598770 cites W2061464631 @default.
• W4321598770 cites W2063367703 @default.
• W4321598770 cites W2064710522 @default.
• W4321598770 cites W2067241533 @default.
• W4321598770 cites W2067698130 @default.
• W4321598770 cites W2075921652 @default.
• W4321598770 cites W2076602698 @default.
• W4321598770 cites W2077496065 @default.
• W4321598770 cites W2078149957 @default.
• W4321598770 cites W2080985035 @default.
• W4321598770 cites W2086951278 @default.
• W4321598770 cites W2092608990 @default.
• W4321598770 cites W2096655776 @default.
• W4321598770 cites W2099348928 @default.
• W4321598770 cites W2102212845 @default.
• W4321598770 cites W2109751424 @default.

• next