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• W4321601860 endingPage "115173" @default.
• W4321601860 startingPage "115173" @default.
• W4321601860 abstract "Due to the extended culture period and various inconveniences in vitro culture, the detection of invasive fungi is rather difficult, leading to high mortality rates of the diseases caused by them. It is, however, crucial for clinical therapy and lowering patient mortality to quickly identify invasive fungus from clinical specimens. A promising non-destructive method for finding fungi is surface-enhanced Raman scattering (SERS), however, its substrate has a low level of selectivity. Clinical sample components can obstruct the target fungi's SERS signal on account of their complexity. Herein, an [email protected] hybrid organic-inorganic nano-catcher was created by using ultrasonic-initiated polymerization. The caspofungin (CAS), a fungus cell wall-targeting drug, is used in this study. We investigated [email protected] as a technique to rapidly extract fungus from complex samples under 3 s. SERS could subsequently be used to instantly identify the fungi that were successfully isolated with an efficacy rate of about 75%. The entire process took just 10 min. This method is an important breakthrough that might be advantageous in terms of the rapid detection of invasive fungi." @default.
• W4321601860 created "2023-02-24" @default.
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• W4321601860 date "2023-05-01" @default.
• W4321601860 modified "2023-10-14" @default.
• W4321601860 title "A cell wall-targeted organic-inorganic hybrid nano-catcher for ultrafast capture and SERS detection of invasive fungi" @default.
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• W4321601860 doi "https://doi.org/10.1016/j.bios.2023.115173" @default.
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