FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4321790614> ?p ?o ?g. }

• W4321790614 abstract "Identifying individual cells or nuclei is often the first step in the analysis of multiplex tissue imaging (MTI) data. Recent efforts to produce plug-and-play, end-to-end MTI analysis tools such as MCMICRO 1 - though groundbreaking in their usability and extensibility - are often unable to provide users guidance regarding the most appropriate models for their segmentation task among an endless proliferation of novel segmentation methods. Unfortunately, evaluating segmentation results on a user's dataset without ground truth labels is either purely subjective or eventually amounts to the task of performing the original, time-intensive annotation. As a consequence, researchers rely on models pre-trained on other large datasets for their unique tasks. Here, we propose a methodological approach for evaluating MTI nuclei segmentation methods in absence of ground truth labels by scoring relatively to a larger ensemble of segmentations. To avoid potential sensitivity to collective bias from the ensemble approach, we refine the ensemble via weighted average across segmentation methods, which we derive from a systematic model ablation study. First, we demonstrate a proof-of-concept and the feasibility of the proposed approach to evaluate segmentation performance in a small dataset with ground truth annotation. To validate the ensemble and demonstrate the importance of our method-specific weighting, we compare the ensemble's detection and pixel-level predictions - derived without supervision - with the data's ground truth labels. Second, we apply the methodology to an unlabeled larger tissue microarray (TMA) dataset, which includes a diverse set of breast cancer phenotypes, and provides decision guidelines for the general user to more easily choose the most suitable segmentation methods for their own dataset by systematically evaluating the performance of individual segmentation approaches in the entire dataset." @default.
• W4321790614 created "2023-02-25" @default.
• W4321790614 creator A5011962080 @default.
• W4321790614 creator A5012617768 @default.
• W4321790614 creator A5013518150 @default.
• W4321790614 creator A5025032203 @default.
• W4321790614 creator A5038190148 @default.
• W4321790614 creator A5070423173 @default.
• W4321790614 date "2023-02-24" @default.
• W4321790614 modified "2023-10-17" @default.
• W4321790614 title "SEG: Segmentation Evaluation in absence of Ground truth labels" @default.
• W4321790614 cites W130387664 @default.
• W4321790614 cites W1901129140 @default.
• W4321790614 cites W2034235577 @default.
• W4321790614 cites W2594608309 @default.
• W4321790614 cites W2595706594 @default.
• W4321790614 cites W2604591951 @default.
• W4321790614 cites W2806070179 @default.
• W4321790614 cites W2832881433 @default.
• W4321790614 cites W2911830042 @default.
• W4321790614 cites W2949238013 @default.
• W4321790614 cites W2963150697 @default.
• W4321790614 cites W2975634117 @default.
• W4321790614 cites W2980998394 @default.
• W4321790614 cites W3087685572 @default.
• W4321790614 cites W3100296314 @default.
• W4321790614 cites W3111521801 @default.
• W4321790614 cites W3153558340 @default.
• W4321790614 cites W3184917240 @default.
• W4321790614 cites W3196890347 @default.
• W4321790614 cites W3214596602 @default.
• W4321790614 cites W3215932031 @default.
• W4321790614 cites W341877867 @default.
• W4321790614 cites W4308147592 @default.
• W4321790614 cites W4308361273 @default.
• W4321790614 cites W4309326436 @default.
• W4321790614 cites W4311486734 @default.
• W4321790614 doi "https://doi.org/10.1101/2023.02.23.529809" @default.
• W4321790614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36865198" @default.
• W4321790614 hasPublicationYear "2023" @default.
• W4321790614 type Work @default.
• W4321790614 citedByCount "0" @default.
• W4321790614 crossrefType "posted-content" @default.
• W4321790614 hasAuthorship W4321790614A5011962080 @default.
• W4321790614 hasAuthorship W4321790614A5012617768 @default.
• W4321790614 hasAuthorship W4321790614A5013518150 @default.
• W4321790614 hasAuthorship W4321790614A5025032203 @default.
• W4321790614 hasAuthorship W4321790614A5038190148 @default.
• W4321790614 hasAuthorship W4321790614A5070423173 @default.
• W4321790614 hasBestOaLocation W43217906141 @default.
• W4321790614 hasConcept C107457646 @default.
• W4321790614 hasConcept C119857082 @default.
• W4321790614 hasConcept C124101348 @default.
• W4321790614 hasConcept C126838900 @default.
• W4321790614 hasConcept C146849305 @default.
• W4321790614 hasConcept C153180895 @default.
• W4321790614 hasConcept C154945302 @default.
• W4321790614 hasConcept C162324750 @default.
• W4321790614 hasConcept C170130773 @default.
• W4321790614 hasConcept C183115368 @default.
• W4321790614 hasConcept C187736073 @default.
• W4321790614 hasConcept C2776321320 @default.
• W4321790614 hasConcept C2780451532 @default.
• W4321790614 hasConcept C41008148 @default.
• W4321790614 hasConcept C45942800 @default.
• W4321790614 hasConcept C71924100 @default.
• W4321790614 hasConcept C89600930 @default.
• W4321790614 hasConceptScore W4321790614C107457646 @default.
• W4321790614 hasConceptScore W4321790614C119857082 @default.
• W4321790614 hasConceptScore W4321790614C124101348 @default.
• W4321790614 hasConceptScore W4321790614C126838900 @default.
• W4321790614 hasConceptScore W4321790614C146849305 @default.
• W4321790614 hasConceptScore W4321790614C153180895 @default.
• W4321790614 hasConceptScore W4321790614C154945302 @default.
• W4321790614 hasConceptScore W4321790614C162324750 @default.
• W4321790614 hasConceptScore W4321790614C170130773 @default.
• W4321790614 hasConceptScore W4321790614C183115368 @default.
• W4321790614 hasConceptScore W4321790614C187736073 @default.
• W4321790614 hasConceptScore W4321790614C2776321320 @default.
• W4321790614 hasConceptScore W4321790614C2780451532 @default.
• W4321790614 hasConceptScore W4321790614C41008148 @default.
• W4321790614 hasConceptScore W4321790614C45942800 @default.
• W4321790614 hasConceptScore W4321790614C71924100 @default.
• W4321790614 hasConceptScore W4321790614C89600930 @default.
• W4321790614 hasLocation W43217906141 @default.
• W4321790614 hasLocation W43217906142 @default.
• W4321790614 hasOpenAccess W4321790614 @default.
• W4321790614 hasPrimaryLocation W43217906141 @default.
• W4321790614 hasRelatedWork W151193258 @default.
• W4321790614 hasRelatedWork W1607472309 @default.
• W4321790614 hasRelatedWork W2130151498 @default.
• W4321790614 hasRelatedWork W2784354871 @default.
• W4321790614 hasRelatedWork W2904499449 @default.
• W4321790614 hasRelatedWork W2952663681 @default.
• W4321790614 hasRelatedWork W4220671204 @default.
• W4321790614 hasRelatedWork W4285046548 @default.
• W4321790614 hasRelatedWork W4285741730 @default.
• W4321790614 hasRelatedWork W4292969247 @default.
• W4321790614 isParatext "false" @default.
• W4321790614 isRetracted "false" @default.

• next