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• W4322496311 abstract "Complete en bloc surgical resection offers the best opportunity for the cure of primary retroperitoneal sarcomas (RPS). The potential for disease recurrence, in the form of both loco-regional recurrence and distant metastases, underpins the rationale for postoperative surveillance. There is a paucity of high-quality evidence underpinning follow-up for RPS patients, and most practice guidelines draw from expert opinion and evidence from soft tissue sarcomas of the extremities. The available observational retrospective data analysis has failed to demonstrate that high-intensity radiological surveillance improves the overall survival in patients. The lack of a robust evidence base has given rise to variations in approaches to post-operative surveillance strategies adopted by specialist centres managing RPS across the world. More high-quality prospective research is needed and planned to more clearly support surveillance approaches that balance oncologic outcomes, patient-centric care, and health service value. Risk stratification tools exist and are available for use in routine practice. Their use will likely support more individualised post-operative surveillance moving forward. Surveillance will likely be underpinned by serial radiological imaging for the medium term. However, developments in genomics offer hope for biomarkers such as ctDNA to impact patient care positively in the future and further support individualised patient care pathways." @default.
• W4322496311 created "2023-02-28" @default.
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• W4322496311 date "2023-02-26" @default.
• W4322496311 modified "2023-10-18" @default.
• W4322496311 title "Surveillance Post Surgery for Retroperitoneal Soft Tissue Sarcoma" @default.
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• W4322496311 doi "https://doi.org/10.3390/curroncol30030211" @default.
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• W4322496311 hasPublicationYear "2023" @default.
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