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- W4322618008 abstract "A 47-year-old Caucasian male with a 2-month history of right upper eyelid swelling (panel A) was referred to the Wills Eye Hospital Ocular Oncology Service with the presumptive diagnosis of conjunctival melanoma. Ocular history was significant for excision of a stye at the same location 3 years before. Examination demonstrated a darkly pigmented upper tarsal conjunctival lesion (panel B), which measured 8 mm in basal diameter and 2 mm in thickness, without any ulceration or primary acquired melanosis. Regional lymph nodes were normal. A posterior lamellar resection of the right upper eyelid was performed. Histopathology demonstrated a cyst filled with light brown pigmented debris (panel C, asterisk) and basophilic bacterial colonies (panel C, arrow) adjacent to a Meibomian gland (panel C, single arrowhead) and conjunctival epithelium (panel C, double arrowhead). The cyst lining was composed of stratified squamous epithelium with eosinophilic delicate keratin cuticle without appreciable granular cell layer (panel D), compatible with a Meibomian duct cyst. The luminal material consisted of a mixture of intact basophilic (panel D, arrow) and degenerated light brown bacterial colonies, filamentous light brown keratin, and cholesterol clefts (panel D, arrowhead). Gram-stain (panel E) highlighted pleomorphic Gram-positive coccobacilli, scattered (panel E, arrowhead) and in irregular aggregates (panel E, arrow).The pigmented nature of this lesion made conjunctival melanoma a compelling diagnosis, but histopathology unmasked the true etiology of a Meibomian duct cyst containing intraluminal bacterial colonies, keratin, and cholesterol." @default.
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- W4322618008 date "2023-02-28" @default.
- W4322618008 modified "2023-10-16" @default.
- W4322618008 title "Infected Pigmented Meibomian Duct Cyst Masquerading as a Conjunctival Melanoma" @default.
- W4322618008 doi "https://doi.org/10.1097/iop.0000000000002336" @default.
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