Matches in SemOpenAlex for { <https://semopenalex.org/work/W4322630209> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W4322630209 endingPage "1191" @default.
- W4322630209 startingPage "1183" @default.
- W4322630209 abstract "The present study was performed to evaluate the effect of intestinal microbiota transplantation (IMT) on intestinal flora and inflammatory factor levels in patients with ulcerative colitis (UC).In this study, 94 UC patients who attended the Department of Proctology or the Department of Gastroenterology departments of Sinopharm Dongfeng General Hospital between April 2021 and April 2022 were identified as research participants and were assigned to the control or Research Groups via the random number table method, with 47 cases in each group. Interventions included oral mesalamine for patients in the control group and oral mesalamine plus IMT for those in the research group. Outcome measures included clinical efficacy, intestinal microbiota score, enteroscopy score, Sutherland index, inflammatory factor level, intestinal mucosal barrier function level, and adverse reactions.Mesalamine plus IMT was associated with significantly higher treatment efficiency (97.8%) versus mesalamine alone (80.85%) (P<0.05). Mesalamine plus IMT provided a better intestinal microbiota balance and milder disease symptoms versus mesalamine, as evidenced by the significantly lower intestinal microbiota scores, colonoscopy scores, and Sutherland index (P<0.05). In post-treatment, patients with IMT exhibited more mitigated inflammatory responses than those without, as shown by the higher levels of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), interleukin-17 (IL-17), and interleukin-23 (IL-23) (P<0.05). Significantly lower D-lactate and serum diamine oxidase (DAO) levels were observed after IMT intervention than those with mesalamine alone (P<0.05). IMT features no significant increase in adverse effects than the control group (P>0.05).IMT efficiently ameliorates the intestinal microbiota conditions of UC patients, mitigates inflammatory responses in the body, and facilitates the restoration of intestinal mucosal barrier function with no significant increase in adverse effects." @default.
- W4322630209 created "2023-03-01" @default.
- W4322630209 creator A5018860616 @default.
- W4322630209 creator A5036016529 @default.
- W4322630209 creator A5089887273 @default.
- W4322630209 date "2023-02-01" @default.
- W4322630209 modified "2023-10-14" @default.
- W4322630209 title "Effect of Intestinal Microbiota Transplantation on Intestinal Flora and Inflammatory Factor Levels in Patients with Ulcerative Colitis" @default.
- W4322630209 cites W2763684605 @default.
- W4322630209 cites W2777011462 @default.
- W4322630209 cites W2782401411 @default.
- W4322630209 cites W2808186686 @default.
- W4322630209 cites W2883758088 @default.
- W4322630209 cites W2886213241 @default.
- W4322630209 cites W2891592698 @default.
- W4322630209 cites W2965587973 @default.
- W4322630209 cites W2976362764 @default.
- W4322630209 cites W2982809154 @default.
- W4322630209 cites W2998718302 @default.
- W4322630209 cites W3008765807 @default.
- W4322630209 cites W3012730985 @default.
- W4322630209 cites W3086885273 @default.
- W4322630209 cites W3087967903 @default.
- W4322630209 cites W3088062854 @default.
- W4322630209 cites W3125037474 @default.
- W4322630209 cites W3126487719 @default.
- W4322630209 cites W3159830390 @default.
- W4322630209 cites W3166135647 @default.
- W4322630209 cites W3167893092 @default.
- W4322630209 cites W3182088130 @default.
- W4322630209 cites W3215577800 @default.
- W4322630209 doi "https://doi.org/10.2147/idr.s394614" @default.
- W4322630209 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36879853" @default.
- W4322630209 hasPublicationYear "2023" @default.
- W4322630209 type Work @default.
- W4322630209 citedByCount "2" @default.
- W4322630209 countsByYear W43226302092023 @default.
- W4322630209 crossrefType "journal-article" @default.
- W4322630209 hasAuthorship W4322630209A5018860616 @default.
- W4322630209 hasAuthorship W4322630209A5036016529 @default.
- W4322630209 hasAuthorship W4322630209A5089887273 @default.
- W4322630209 hasBestOaLocation W43226302091 @default.
- W4322630209 hasConcept C121608353 @default.
- W4322630209 hasConcept C126322002 @default.
- W4322630209 hasConcept C181199279 @default.
- W4322630209 hasConcept C185592680 @default.
- W4322630209 hasConcept C197934379 @default.
- W4322630209 hasConcept C2778260677 @default.
- W4322630209 hasConcept C2778435480 @default.
- W4322630209 hasConcept C2779053737 @default.
- W4322630209 hasConcept C2779134260 @default.
- W4322630209 hasConcept C2779174533 @default.
- W4322630209 hasConcept C2780479503 @default.
- W4322630209 hasConcept C526805850 @default.
- W4322630209 hasConcept C55493867 @default.
- W4322630209 hasConcept C71924100 @default.
- W4322630209 hasConcept C90924648 @default.
- W4322630209 hasConceptScore W4322630209C121608353 @default.
- W4322630209 hasConceptScore W4322630209C126322002 @default.
- W4322630209 hasConceptScore W4322630209C181199279 @default.
- W4322630209 hasConceptScore W4322630209C185592680 @default.
- W4322630209 hasConceptScore W4322630209C197934379 @default.
- W4322630209 hasConceptScore W4322630209C2778260677 @default.
- W4322630209 hasConceptScore W4322630209C2778435480 @default.
- W4322630209 hasConceptScore W4322630209C2779053737 @default.
- W4322630209 hasConceptScore W4322630209C2779134260 @default.
- W4322630209 hasConceptScore W4322630209C2779174533 @default.
- W4322630209 hasConceptScore W4322630209C2780479503 @default.
- W4322630209 hasConceptScore W4322630209C526805850 @default.
- W4322630209 hasConceptScore W4322630209C55493867 @default.
- W4322630209 hasConceptScore W4322630209C71924100 @default.
- W4322630209 hasConceptScore W4322630209C90924648 @default.
- W4322630209 hasLocation W43226302091 @default.
- W4322630209 hasLocation W43226302092 @default.
- W4322630209 hasLocation W43226302093 @default.
- W4322630209 hasOpenAccess W4322630209 @default.
- W4322630209 hasPrimaryLocation W43226302091 @default.
- W4322630209 hasRelatedWork W2047076379 @default.
- W4322630209 hasRelatedWork W2078745520 @default.
- W4322630209 hasRelatedWork W2263605371 @default.
- W4322630209 hasRelatedWork W2352254143 @default.
- W4322630209 hasRelatedWork W2355129079 @default.
- W4322630209 hasRelatedWork W2382465907 @default.
- W4322630209 hasRelatedWork W2386497540 @default.
- W4322630209 hasRelatedWork W2407927805 @default.
- W4322630209 hasRelatedWork W3032188930 @default.
- W4322630209 hasRelatedWork W4321748671 @default.
- W4322630209 hasVolume "Volume 16" @default.
- W4322630209 isParatext "false" @default.
- W4322630209 isRetracted "false" @default.
- W4322630209 workType "article" @default.