Matches in SemOpenAlex for { <https://semopenalex.org/work/W4322729863> ?p ?o ?g. }
- W4322729863 endingPage "102296" @default.
- W4322729863 startingPage "102296" @default.
- W4322729863 abstract "Inborn errors of immunity (IEI) delineate redundant and essential defense mechanisms in humans. We review 15 autosomal-dominant (AD) or -recessive (AR) IEI involving 11 transcription factors (TFs) and impairing interferon-gamma (IFN-γ) immunity, conferring a predisposition to mycobacterial diseases. We consider three mechanism-based categories: 1) IEI mainly affecting myeloid compartment development (AD GATA2 and AR and AD IRF8 deficiencies), 2) IEI mainly affecting lymphoid compartment development (AR FOXN1, AR PAX1, AR RORγ/RORγT, AR T-bet, AR c-Rel, AD STAT3 gain-of-function (GOF), and loss-of-function (LOF) deficiencies), and 3) IEI mainly affecting myeloid and/or lymphoid function (AR and AD STAT1 LOF, AD STAT1 GOF, AR IRF1, and AD NFKB1 deficiencies). We discuss the contribution of the discovery and study of inborn errors of TFs essential for host defense against mycobacteria to molecular and cellular analyses of human IFN-γ immunity." @default.
- W4322729863 created "2023-03-03" @default.
- W4322729863 creator A5004602514 @default.
- W4322729863 creator A5026924923 @default.
- W4322729863 creator A5053742498 @default.
- W4322729863 creator A5079652754 @default.
- W4322729863 creator A5081521127 @default.
- W4322729863 creator A5083070243 @default.
- W4322729863 date "2023-04-01" @default.
- W4322729863 modified "2023-10-18" @default.
- W4322729863 title "Inborn errors of human transcription factors governing IFN-γ antimycobacterial immunity" @default.
- W4322729863 cites W1581513481 @default.
- W4322729863 cites W1622233056 @default.
- W4322729863 cites W1748436622 @default.
- W4322729863 cites W1967261754 @default.
- W4322729863 cites W1985929162 @default.
- W4322729863 cites W1999234197 @default.
- W4322729863 cites W2043901802 @default.
- W4322729863 cites W2079178172 @default.
- W4322729863 cites W2115068324 @default.
- W4322729863 cites W2120081319 @default.
- W4322729863 cites W2123093300 @default.
- W4322729863 cites W2123358740 @default.
- W4322729863 cites W2142017607 @default.
- W4322729863 cites W2151513117 @default.
- W4322729863 cites W2153570621 @default.
- W4322729863 cites W2167468135 @default.
- W4322729863 cites W2467020097 @default.
- W4322729863 cites W2574819148 @default.
- W4322729863 cites W2767814127 @default.
- W4322729863 cites W2803146240 @default.
- W4322729863 cites W2887504455 @default.
- W4322729863 cites W2906653622 @default.
- W4322729863 cites W2914014785 @default.
- W4322729863 cites W2923669061 @default.
- W4322729863 cites W2944041837 @default.
- W4322729863 cites W2946683788 @default.
- W4322729863 cites W3006500173 @default.
- W4322729863 cites W3007528900 @default.
- W4322729863 cites W3016219406 @default.
- W4322729863 cites W3044172541 @default.
- W4322729863 cites W3081194337 @default.
- W4322729863 cites W3111053993 @default.
- W4322729863 cites W3120175537 @default.
- W4322729863 cites W3123408441 @default.
- W4322729863 cites W3141879899 @default.
- W4322729863 cites W3157791404 @default.
- W4322729863 cites W3161056637 @default.
- W4322729863 cites W3169017175 @default.
- W4322729863 cites W3169756039 @default.
- W4322729863 cites W3175122226 @default.
- W4322729863 cites W3177407231 @default.
- W4322729863 cites W3181840845 @default.
- W4322729863 cites W3184740813 @default.
- W4322729863 cites W3197908941 @default.
- W4322729863 cites W3198172671 @default.
- W4322729863 cites W3205680403 @default.
- W4322729863 cites W3208803788 @default.
- W4322729863 cites W4220789661 @default.
- W4322729863 cites W4283363193 @default.
- W4322729863 cites W4286586721 @default.
- W4322729863 cites W4292240525 @default.
- W4322729863 cites W4295507656 @default.
- W4322729863 cites W4302278284 @default.
- W4322729863 cites W4304183042 @default.
- W4322729863 cites W4308485012 @default.
- W4322729863 cites W4318987669 @default.
- W4322729863 cites W4320032950 @default.
- W4322729863 doi "https://doi.org/10.1016/j.coi.2023.102296" @default.
- W4322729863 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36867972" @default.
- W4322729863 hasPublicationYear "2023" @default.
- W4322729863 type Work @default.
- W4322729863 citedByCount "0" @default.
- W4322729863 crossrefType "journal-article" @default.
- W4322729863 hasAuthorship W4322729863A5004602514 @default.
- W4322729863 hasAuthorship W4322729863A5026924923 @default.
- W4322729863 hasAuthorship W4322729863A5053742498 @default.
- W4322729863 hasAuthorship W4322729863A5079652754 @default.
- W4322729863 hasAuthorship W4322729863A5081521127 @default.
- W4322729863 hasAuthorship W4322729863A5083070243 @default.
- W4322729863 hasBestOaLocation W43227298631 @default.
- W4322729863 hasConcept C104317684 @default.
- W4322729863 hasConcept C117705580 @default.
- W4322729863 hasConcept C203014093 @default.
- W4322729863 hasConcept C2776178377 @default.
- W4322729863 hasConcept C2777003663 @default.
- W4322729863 hasConcept C2779282312 @default.
- W4322729863 hasConcept C2779341262 @default.
- W4322729863 hasConcept C54355233 @default.
- W4322729863 hasConcept C74737994 @default.
- W4322729863 hasConcept C86339819 @default.
- W4322729863 hasConcept C86803240 @default.
- W4322729863 hasConcept C8891405 @default.
- W4322729863 hasConceptScore W4322729863C104317684 @default.
- W4322729863 hasConceptScore W4322729863C117705580 @default.
- W4322729863 hasConceptScore W4322729863C203014093 @default.
- W4322729863 hasConceptScore W4322729863C2776178377 @default.
- W4322729863 hasConceptScore W4322729863C2777003663 @default.