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• W4322740947 abstract "Research Objectives To investigate the relationship between muscle strength and osteoporosis and the effect on health-related quality of life (QOL) in Korea. Design This is an observational study. We used the data from the Korea National Health and Nutrition Examination Survey (KNHANES) from 2015 to 2018. Setting The general community. Participants We analyzed the data of 13,966 people over 40-year-old provided by the KNHANES 2015-2018. Interventions N/A. Main Outcome Measures We applied multiple logistic regression analysis to investigate the relationship between handgrip strength (HGS) with the presence of osteoporosis and health-related QOL that was assessed by the European Quality of Life Scale-Five dimensions (EQ-5D). Results Females diagnosed with osteoporosis showed significantly weaker HGS than those without osteoporosis. However, there was no significant difference in males. People with weak HGS generally showed lower EQ-5D values than those with strong HGS. The quality of life of those diagnosed with osteoporosis was significantly reduced in both the strong and weak HGS groups. We calculated the odds ratios of each dimension of EQ-5D of osteoporosis patients according to the HGS based on the values of healthy people with strong HGS. Among the strong HGS group, osteoporosis patients showed the odds ratios of 1.855 (95% CI; 1.504-2.287) in mobility, 1.390 (0.924-2.093) in self-care, 1.503 (1.143-1.978) in usual activity, 1.484 (1.250-1.761) in pain/discomfort, and 1.518 (1.189-1.939) in anxiety/depression. In osteoporosis patients with weak HGS, the odds ratios were 2.675 (2.082-3.439) in mobility, 2.625 (1.814-3.800) in self-care, 2.359 (1.765-3.152) in usual activity, 1.964 (1.559-2.474) in pain/discomfort, and 1.754 (1.341-2.294) in anxiety/depression. Conclusions Our study confirmed that low HGS with the presence of osteoporosis is correlated with low health-related QOL. Thus, HGS may be a practical factor to predict QOL in people with osteoporosis. Author(s) Disclosures We have no conflicts of interest to disclose. To investigate the relationship between muscle strength and osteoporosis and the effect on health-related quality of life (QOL) in Korea. This is an observational study. We used the data from the Korea National Health and Nutrition Examination Survey (KNHANES) from 2015 to 2018. The general community. We analyzed the data of 13,966 people over 40-year-old provided by the KNHANES 2015-2018. N/A. We applied multiple logistic regression analysis to investigate the relationship between handgrip strength (HGS) with the presence of osteoporosis and health-related QOL that was assessed by the European Quality of Life Scale-Five dimensions (EQ-5D). Females diagnosed with osteoporosis showed significantly weaker HGS than those without osteoporosis. However, there was no significant difference in males. People with weak HGS generally showed lower EQ-5D values than those with strong HGS. The quality of life of those diagnosed with osteoporosis was significantly reduced in both the strong and weak HGS groups. We calculated the odds ratios of each dimension of EQ-5D of osteoporosis patients according to the HGS based on the values of healthy people with strong HGS. Among the strong HGS group, osteoporosis patients showed the odds ratios of 1.855 (95% CI; 1.504-2.287) in mobility, 1.390 (0.924-2.093) in self-care, 1.503 (1.143-1.978) in usual activity, 1.484 (1.250-1.761) in pain/discomfort, and 1.518 (1.189-1.939) in anxiety/depression. In osteoporosis patients with weak HGS, the odds ratios were 2.675 (2.082-3.439) in mobility, 2.625 (1.814-3.800) in self-care, 2.359 (1.765-3.152) in usual activity, 1.964 (1.559-2.474) in pain/discomfort, and 1.754 (1.341-2.294) in anxiety/depression. Our study confirmed that low HGS with the presence of osteoporosis is correlated with low health-related QOL. Thus, HGS may be a practical factor to predict QOL in people with osteoporosis." @default.
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• W4322740947 date "2023-03-01" @default.
• W4322740947 modified "2023-09-24" @default.
• W4322740947 title "Relationship Between Muscle Strength and Osteoporosis and Its Effect on The Health-Related Quality of Life" @default.
• W4322740947 doi "https://doi.org/10.1016/j.apmr.2022.12.140" @default.
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