Matches in SemOpenAlex for { <https://semopenalex.org/work/W4322757686> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W4322757686 endingPage "286" @default.
- W4322757686 startingPage "281" @default.
- W4322757686 abstract "Two-dimensional liquid chromatography (2D-LC) has gained increased attention because of its high peak capacity for separating complex samples. However, preparative 2D-LC aimed at isolating compounds is significantly different compared with one-dimensional liquid chromatography (1D-LC) in terms of method development and system configuration; thus, it is less developed than its analytical counterpart. The use of 2D-LC in large-scale product preparation has rarely been reported. Hence, a preparative 2D-LC system was developed in this study. The system was composed of one set of preparative LC modules as a separation system, with a dilution pump, switch valves, and trap column array as the interface, to enable the simultaneous isolation of several compounds. Tobacco was used as a sample, and the developed system was applied to isolate nicotine, chlorogenic acid, rutin, and solanesol. The chromatographic conditions were developed by investigating the trapping efficiency of different types of trap column packings, and chromatographic behaviors under different overload conditions. The four compounds were isolated in one 2D-LC run with high purity. The developed system features low cost because it employs medium-pressure isolation, excellent automation owing to its use of an online column switch, high stability, and capability for large-scale production. The isolation of chemicals from tobacco leaves as pharmaceutical raw materials could aid in the development of the tobacco industry and promote the local agricultural economy." @default.
- W4322757686 created "2023-03-03" @default.
- W4322757686 creator A5016711247 @default.
- W4322757686 creator A5048989190 @default.
- W4322757686 creator A5062200379 @default.
- W4322757686 creator A5068925729 @default.
- W4322757686 creator A5070602424 @default.
- W4322757686 creator A5081269100 @default.
- W4322757686 creator A5085576353 @default.
- W4322757686 creator A5086069864 @default.
- W4322757686 date "2023-03-01" @default.
- W4322757686 modified "2023-09-30" @default.
- W4322757686 title "Trapping array-based preparative two-dimensional liquid chromatography for the purification of four components in tobacco leaves" @default.
- W4322757686 cites W1972922245 @default.
- W4322757686 cites W2048194497 @default.
- W4322757686 cites W2085977899 @default.
- W4322757686 cites W2164706744 @default.
- W4322757686 cites W2409885957 @default.
- W4322757686 cites W2553359234 @default.
- W4322757686 cites W2597956626 @default.
- W4322757686 cites W2963712532 @default.
- W4322757686 cites W2981992350 @default.
- W4322757686 cites W3154623034 @default.
- W4322757686 cites W3217250596 @default.
- W4322757686 cites W4210826848 @default.
- W4322757686 doi "https://doi.org/10.3724/sp.j.1123.2022.08021" @default.
- W4322757686 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36861212" @default.
- W4322757686 hasPublicationYear "2023" @default.
- W4322757686 type Work @default.
- W4322757686 citedByCount "0" @default.
- W4322757686 crossrefType "journal-article" @default.
- W4322757686 hasAuthorship W4322757686A5016711247 @default.
- W4322757686 hasAuthorship W4322757686A5048989190 @default.
- W4322757686 hasAuthorship W4322757686A5062200379 @default.
- W4322757686 hasAuthorship W4322757686A5068925729 @default.
- W4322757686 hasAuthorship W4322757686A5070602424 @default.
- W4322757686 hasAuthorship W4322757686A5081269100 @default.
- W4322757686 hasAuthorship W4322757686A5085576353 @default.
- W4322757686 hasAuthorship W4322757686A5086069864 @default.
- W4322757686 hasBestOaLocation W43227576862 @default.
- W4322757686 hasConcept C121332964 @default.
- W4322757686 hasConcept C179998833 @default.
- W4322757686 hasConcept C185592680 @default.
- W4322757686 hasConcept C43617362 @default.
- W4322757686 hasConcept C63258622 @default.
- W4322757686 hasConcept C96618451 @default.
- W4322757686 hasConcept C97355855 @default.
- W4322757686 hasConceptScore W4322757686C121332964 @default.
- W4322757686 hasConceptScore W4322757686C179998833 @default.
- W4322757686 hasConceptScore W4322757686C185592680 @default.
- W4322757686 hasConceptScore W4322757686C43617362 @default.
- W4322757686 hasConceptScore W4322757686C63258622 @default.
- W4322757686 hasConceptScore W4322757686C96618451 @default.
- W4322757686 hasConceptScore W4322757686C97355855 @default.
- W4322757686 hasIssue "3" @default.
- W4322757686 hasLocation W43227576861 @default.
- W4322757686 hasLocation W43227576862 @default.
- W4322757686 hasLocation W43227576863 @default.
- W4322757686 hasOpenAccess W4322757686 @default.
- W4322757686 hasPrimaryLocation W43227576861 @default.
- W4322757686 hasRelatedWork W2011071533 @default.
- W4322757686 hasRelatedWork W2037171905 @default.
- W4322757686 hasRelatedWork W2064394405 @default.
- W4322757686 hasRelatedWork W2066554088 @default.
- W4322757686 hasRelatedWork W2068118433 @default.
- W4322757686 hasRelatedWork W2417209194 @default.
- W4322757686 hasRelatedWork W2911853957 @default.
- W4322757686 hasRelatedWork W3191053664 @default.
- W4322757686 hasRelatedWork W2524959782 @default.
- W4322757686 hasRelatedWork W2601117855 @default.
- W4322757686 hasVolume "41" @default.
- W4322757686 isParatext "false" @default.
- W4322757686 isRetracted "false" @default.
- W4322757686 workType "article" @default.