FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4322771045> ?p ?o ?g. }

• W4322771045 endingPage "36" @default.
• W4322771045 startingPage "P1" @default.
• W4322771045 abstract "Abstract Introduction: Long QT syndrome is a common cardiotoxic side effect of various anti-tumor drugs. Previous cardiological monitoring of oncological patients is primarily complex and requires for non-internal oncologists a consultation. Therefore, the QTc-Tracker smartphone APP was developed, which enabled a tele-cardiological diagnosis of the QTc time with standard single-lead ECG devices. As a result, diagnosis times could already be reduced by 99%. The further development examined an automatic determination of the QT time using the smartphone APP. However, since single-lead ECG devices are significantly more susceptible to interference, the determination of the QT time is more complex than with 12-lead ECGs. Methods: The QTc-Tracker smartphone APP was developed to determine the QT time. Self-tracker single-lead ECG devices were used to record the lead I signal. The ECG recordings were analyzed in the APP and passed on to an external cardiologist as reference. The APP used artificial intelligence and was trained in the first phase and validated in the second phase. The first phase aimed to improve QT time detection. The results of the APP were compared with the findings of the external cardiologist. In both phases, ECGs from breast cancer patients receiving ribociclib were used. Results: A total of 1889 single-lead ECGs were carried out. 248 of these could not be evaluated (13%). QTc prolongation, according to CTCAE, was diagnosed in 41 cases (2.5%). 878 of the evaluable ECGs were used for the training phase and 763 for the evaluation phase. In the first group (before the improvement), the sensitivity to automatically detect a prolongation of the QT time was 36%, and the specificity was 96%. In the evaluation collective (after the training), the sensitivity went up to 85%, and the specificity was unchanged at 96%. Conclusions: The trained method of the QTc tracker is able to reliably detect a QT time lengthening even without a cardiological diagnosis only by using single-lead self-tracker ECG’s. In the rare cases in which an elongation was not detected, the cardiac diagnosis was only a few milliseconds above the threshold value. This artificial intelligence-based smartphone APP is not intended to replace the cardiological diagnosis, but it can simplify routine processes and help to decide which patients need a cardiological examination more urgently. Citation Format: Timo Schinköthe, Christian Horst Tonk, Nadia Harbeck, Vanda Carmelo, Joana Gomes Feliciano, Rachel Wuerstlein, Sherko Küemmel, Annette Schmidt. AI-Based Smartphone App Using a Single-Lead ECG for Automated QTc Diagnostics in Oncology [abstract]. In: Proceedings of the 2022 San Antonio Breast Cancer Symposium; 2022 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2023;83(5 Suppl):Abstract nr P1-05-36." @default.
• W4322771045 created "2023-03-03" @default.
• W4322771045 creator A5006268438 @default.
• W4322771045 creator A5008410755 @default.
• W4322771045 creator A5014814095 @default.
• W4322771045 creator A5027231412 @default.
• W4322771045 creator A5031237592 @default.
• W4322771045 creator A5031666050 @default.
• W4322771045 creator A5044569128 @default.
• W4322771045 creator A5063023965 @default.
• W4322771045 date "2023-03-01" @default.
• W4322771045 modified "2023-10-16" @default.
• W4322771045 title "Abstract P1-05-36: AI-Based Smartphone App Using a Single-Lead ECG for Automated QTc Diagnostics in Oncology" @default.
• W4322771045 doi "https://doi.org/10.1158/1538-7445.sabcs22-p1-05-36" @default.
• W4322771045 hasPublicationYear "2023" @default.
• W4322771045 type Work @default.
• W4322771045 citedByCount "0" @default.
• W4322771045 crossrefType "journal-article" @default.
• W4322771045 hasAuthorship W4322771045A5006268438 @default.
• W4322771045 hasAuthorship W4322771045A5008410755 @default.
• W4322771045 hasAuthorship W4322771045A5014814095 @default.
• W4322771045 hasAuthorship W4322771045A5027231412 @default.
• W4322771045 hasAuthorship W4322771045A5031237592 @default.
• W4322771045 hasAuthorship W4322771045A5031666050 @default.
• W4322771045 hasAuthorship W4322771045A5044569128 @default.
• W4322771045 hasAuthorship W4322771045A5063023965 @default.
• W4322771045 hasConcept C108827166 @default.
• W4322771045 hasConcept C114793014 @default.
• W4322771045 hasConcept C118441451 @default.
• W4322771045 hasConcept C121608353 @default.
• W4322771045 hasConcept C126322002 @default.
• W4322771045 hasConcept C127313418 @default.
• W4322771045 hasConcept C164705383 @default.
• W4322771045 hasConcept C2777093003 @default.
• W4322771045 hasConcept C2779703243 @default.
• W4322771045 hasConcept C2780040984 @default.
• W4322771045 hasConcept C3017619522 @default.
• W4322771045 hasConcept C41008148 @default.
• W4322771045 hasConcept C530470458 @default.
• W4322771045 hasConcept C71924100 @default.
• W4322771045 hasConceptScore W4322771045C108827166 @default.
• W4322771045 hasConceptScore W4322771045C114793014 @default.
• W4322771045 hasConceptScore W4322771045C118441451 @default.
• W4322771045 hasConceptScore W4322771045C121608353 @default.
• W4322771045 hasConceptScore W4322771045C126322002 @default.
• W4322771045 hasConceptScore W4322771045C127313418 @default.
• W4322771045 hasConceptScore W4322771045C164705383 @default.
• W4322771045 hasConceptScore W4322771045C2777093003 @default.
• W4322771045 hasConceptScore W4322771045C2779703243 @default.
• W4322771045 hasConceptScore W4322771045C2780040984 @default.
• W4322771045 hasConceptScore W4322771045C3017619522 @default.
• W4322771045 hasConceptScore W4322771045C41008148 @default.
• W4322771045 hasConceptScore W4322771045C530470458 @default.
• W4322771045 hasConceptScore W4322771045C71924100 @default.
• W4322771045 hasIssue "5_Supplement" @default.
• W4322771045 hasLocation W43227710451 @default.
• W4322771045 hasOpenAccess W4322771045 @default.
• W4322771045 hasPrimaryLocation W43227710451 @default.
• W4322771045 hasRelatedWork W1964319858 @default.
• W4322771045 hasRelatedWork W2012229945 @default.
• W4322771045 hasRelatedWork W2030546041 @default.
• W4322771045 hasRelatedWork W2035945489 @default.
• W4322771045 hasRelatedWork W2041799708 @default.
• W4322771045 hasRelatedWork W2058526985 @default.
• W4322771045 hasRelatedWork W2058761320 @default.
• W4322771045 hasRelatedWork W2140890446 @default.
• W4322771045 hasRelatedWork W2789577935 @default.
• W4322771045 hasRelatedWork W4380730055 @default.
• W4322771045 hasVolume "83" @default.
• W4322771045 isParatext "false" @default.
• W4322771045 isRetracted "false" @default.
• W4322771045 workType "article" @default.