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- W4322775402 endingPage "429" @default.
- W4322775402 startingPage "429" @default.
- W4322775402 abstract "Based on functional magnetic resonance imaging and multilayer dynamic network model, the brain network’s quantified temporal stability has shown potential in predicting altered brain functions. This manuscript aims to summarize current knowledge, clinical research progress, and future perspectives on brain network’s temporal stability. There are a variety of widely used measures of temporal stability such as the variance/standard deviation of dynamic functional connectivity strengths, the temporal variability, the flexibility (switching rate), and the temporal clustering coefficient, while there is no consensus to date which measure is the best. The temporal stability of brain networks may be associated with several factors such as sex, age, cognitive functions, head motion, circadian rhythm, and data preprocessing/analyzing strategies, which should be considered in clinical studies. Multiple common psychiatric disorders such as schizophrenia, major depressive disorder, and bipolar disorder have been found to be related to altered temporal stability, especially during the resting state; generally, both excessively decreased and increased temporal stabilities were thought to reflect disorder-related brain dysfunctions. However, the measures of temporal stability are still far from applications in clinical diagnoses for neuropsychiatric disorders partly because of the divergent results. Further studies with larger samples and in transdiagnostic (including schizoaffective disorder) subjects are warranted." @default.
- W4322775402 created "2023-03-03" @default.
- W4322775402 creator A5005067794 @default.
- W4322775402 creator A5011181533 @default.
- W4322775402 creator A5080858187 @default.
- W4322775402 date "2023-03-01" @default.
- W4322775402 modified "2023-10-14" @default.
- W4322775402 title "Temporal Stability of the Dynamic Resting-State Functional Brain Network: Current Measures, Clinical Research Progress, and Future Perspectives" @default.
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