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- W4323025737 abstract "The realization of drug-target interaction plays important role in many processes that determine the fate of a drug and its eventual therapeutic effects in practice. This makes it critical to fundamental research of understanding biological processes and the efforts to develop new therapeutic molecules. In this chapter, we summarize several key biochemical parameters, such as binding affinity and kinetics, dynamic conformational ensembles of drug targets, drug resistance time, rebinding, binding thermodynamics, and ligand efficiency." @default.
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- W4323025737 date "2023-01-01" @default.
- W4323025737 modified "2023-09-30" @default.
- W4323025737 title "Key Biochemical Aspects of Drug-Target Interactions" @default.
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- W4323025737 doi "https://doi.org/10.1007/978-981-99-0078-7_4" @default.
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