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• W4323046310 abstract "A novel aptamer-based fluorescent-sensing platform with a triple-helix molecular switch (THMS) was proposed as a switch for detecting the arsenic(III) ion. The triple helix structure was prepared by binding a signal transduction probe and arsenic aptamer. Additionally, the signal transduction probe labeled with fluorophore (FAM) and quencher (BHQ1) was employed as a signal indicator. The proposed aptasensor is rapid, simple and sensitive, with a limit of detection of 69.95 nM. The decrease in peak fluorescence intensity shows a linear dependence, with the concentration of As(III) in the range of 0.1 µM to 2.5 µM. The whole detection process takes 30 min. Moreover, the THMS-based aptasensor was also successfully used to detect As(III) in a real sample of Huangpu River water with good recoveries. The aptamer-based THMS also presents distinct advantages in stability and selectivity. The proposed strategy developed herein can be extensively applied in the field of food inspection." @default.
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• W4323046310 date "2023-03-03" @default.
• W4323046310 modified "2023-10-17" @default.
• W4323046310 title "A Novel Fluorescent Aptasensor for Arsenic(III) Detection Based on a Triple-Helix Molecular Switch" @default.
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• W4323046310 doi "https://doi.org/10.3390/molecules28052341" @default.
• W4323046310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36903586" @default.
• W4323046310 hasPublicationYear "2023" @default.
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