Matches in SemOpenAlex for { <https://semopenalex.org/work/W4323269184> ?p ?o ?g. }
- W4323269184 endingPage "102869" @default.
- W4323269184 startingPage "102869" @default.
- W4323269184 abstract "Over the years, layered double hydroxides (LDHs) hold a specific position in biomedicine due to their tunable chemical composition and appropriate structural properties. However, LDHs lack adequate sensitivity for active targeting because of less active surface area and low mechanical strength in physiological conditions. The exploitation of eco-friendly materials, such as chitosan (CS), for surface engineering of LDHs, whose payloads are transferred only under certain conditions, can help develop stimuli-responsive materials owing to high biosafety and unique mechanical strength. We aim to render a well-oriented scenario toward the latest achievements of a bottom-up technology relying on the surface functionalization of LDHs to fabricate functional formulations with promoted bio-functionality and high encapsulation efficiency for various bioactives. Many efforts have been devoted to critical aspects of LDHs, including systemic biosafety and the suitability for developing multicomponent systems via integration with therapeutic modalities, which are thoroughly discussed herein. In addition, a comprehensive discussion was provided for the recent progress in the emergence of CS-coated LDHs. Finally, the challenges and future perspectives in the fabrication of efficient CS-LDHs in biomedicine are considered, with a special focus on cancer treatment." @default.
- W4323269184 created "2023-03-06" @default.
- W4323269184 creator A5011536936 @default.
- W4323269184 creator A5054559721 @default.
- W4323269184 creator A5061706328 @default.
- W4323269184 creator A5081118858 @default.
- W4323269184 date "2023-04-01" @default.
- W4323269184 modified "2023-09-29" @default.
- W4323269184 title "State-of-the-art advancement of surface functionalized layered double hydroxides for cell-specific targeting of therapeutics" @default.
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