Matches in SemOpenAlex for { <https://semopenalex.org/work/W4323275735> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W4323275735 endingPage "108584" @default.
- W4323275735 startingPage "108584" @default.
- W4323275735 abstract "Fluazinam exhibits rapid degradation in some vegetable matrixes. The degradation products may pose risk for human health. In the present study, three degradation products of fluazinam in vegetables have been identified, named as sulfhydryl fluazinam, hydroxyl fluazinam, and amine fluazinam. Among them, sulfhydryl fluazinam has not been previously reported. Quantitative/semi-quantitative method for simultaneous analysis of fluazinam and the three degradation products was developed using QuEChERS in combination of HPLC-MS/MS. The proposed analytical method was further applied in monitoring fluazinam and its degradation products in fluazinam-processed vegetables. As a result, sulfhydryl fluazinam was demonstrated to be a characteristic degradation product of fluazinam in the sulphur-rich vegetables with transformation rates of above 10.0% within 60.0 min. In addition, we found for the first time that sulfhydrylation of pesticide occurred in putrid vegetable samples covering various plant families. The result contributed to discovery of the overlooked degradation pathways of pesticides in vegetables. Among fluazinam and the three degradation products, amine fluazinam was predicted to have highest toxicity, followed by sulfhydryl fluazinam and fluazinam, whereas hydroxyl fluazinam displayed the lowest toxicity. Cytotoxicity experiments in BRL-3A cells showed that toxicity of sulfhydryl fluazinam was comparable to that of fluazinam. In short-term oral studies in mice, liver appeared to be a target organ for sulfhydryl fluazinam. The present study not only provides an efficient analysis method, but also inspires further comprehensive risk assessment of fluazinam and its degradation products in vegetables." @default.
- W4323275735 created "2023-03-06" @default.
- W4323275735 creator A5015105154 @default.
- W4323275735 creator A5015746962 @default.
- W4323275735 creator A5026250667 @default.
- W4323275735 creator A5031139358 @default.
- W4323275735 creator A5032020402 @default.
- W4323275735 creator A5048639051 @default.
- W4323275735 creator A5062500062 @default.
- W4323275735 creator A5064847979 @default.
- W4323275735 creator A5091161457 @default.
- W4323275735 date "2023-07-01" @default.
- W4323275735 modified "2023-09-25" @default.
- W4323275735 title "Untargeted screening, quantitative analysis, and toxicity estimation of degradation products of fluazinam in vegetables" @default.
- W4323275735 cites W1993321915 @default.
- W4323275735 cites W2028357718 @default.
- W4323275735 cites W2049532169 @default.
- W4323275735 cites W2052086694 @default.
- W4323275735 cites W2060100181 @default.
- W4323275735 cites W2065466119 @default.
- W4323275735 cites W2067394682 @default.
- W4323275735 cites W2067978493 @default.
- W4323275735 cites W2074102476 @default.
- W4323275735 cites W2087852258 @default.
- W4323275735 cites W2133823221 @default.
- W4323275735 cites W2330890636 @default.
- W4323275735 cites W2504405913 @default.
- W4323275735 cites W2790938100 @default.
- W4323275735 cites W2917378087 @default.
- W4323275735 cites W2996942315 @default.
- W4323275735 cites W3133220865 @default.
- W4323275735 cites W3155774250 @default.
- W4323275735 cites W4241370025 @default.
- W4323275735 cites W4289260659 @default.
- W4323275735 cites W76108819 @default.
- W4323275735 doi "https://doi.org/10.1016/j.microc.2023.108584" @default.
- W4323275735 hasPublicationYear "2023" @default.
- W4323275735 type Work @default.
- W4323275735 citedByCount "0" @default.
- W4323275735 crossrefType "journal-article" @default.
- W4323275735 hasAuthorship W4323275735A5015105154 @default.
- W4323275735 hasAuthorship W4323275735A5015746962 @default.
- W4323275735 hasAuthorship W4323275735A5026250667 @default.
- W4323275735 hasAuthorship W4323275735A5031139358 @default.
- W4323275735 hasAuthorship W4323275735A5032020402 @default.
- W4323275735 hasAuthorship W4323275735A5048639051 @default.
- W4323275735 hasAuthorship W4323275735A5062500062 @default.
- W4323275735 hasAuthorship W4323275735A5064847979 @default.
- W4323275735 hasAuthorship W4323275735A5091161457 @default.
- W4323275735 hasConcept C106848363 @default.
- W4323275735 hasConcept C161176658 @default.
- W4323275735 hasConcept C178790620 @default.
- W4323275735 hasConcept C185592680 @default.
- W4323275735 hasConcept C2775926907 @default.
- W4323275735 hasConcept C29730261 @default.
- W4323275735 hasConcept C43617362 @default.
- W4323275735 hasConcept C6557445 @default.
- W4323275735 hasConcept C86803240 @default.
- W4323275735 hasConceptScore W4323275735C106848363 @default.
- W4323275735 hasConceptScore W4323275735C161176658 @default.
- W4323275735 hasConceptScore W4323275735C178790620 @default.
- W4323275735 hasConceptScore W4323275735C185592680 @default.
- W4323275735 hasConceptScore W4323275735C2775926907 @default.
- W4323275735 hasConceptScore W4323275735C29730261 @default.
- W4323275735 hasConceptScore W4323275735C43617362 @default.
- W4323275735 hasConceptScore W4323275735C6557445 @default.
- W4323275735 hasConceptScore W4323275735C86803240 @default.
- W4323275735 hasFunder F4320321001 @default.
- W4323275735 hasFunder F4320323155 @default.
- W4323275735 hasLocation W43232757351 @default.
- W4323275735 hasOpenAccess W4323275735 @default.
- W4323275735 hasPrimaryLocation W43232757351 @default.
- W4323275735 hasRelatedWork W2030706651 @default.
- W4323275735 hasRelatedWork W2033468598 @default.
- W4323275735 hasRelatedWork W2034408121 @default.
- W4323275735 hasRelatedWork W2198245078 @default.
- W4323275735 hasRelatedWork W2610216768 @default.
- W4323275735 hasRelatedWork W2762460123 @default.
- W4323275735 hasRelatedWork W2953781999 @default.
- W4323275735 hasRelatedWork W3024360468 @default.
- W4323275735 hasRelatedWork W3153585288 @default.
- W4323275735 hasRelatedWork W4282978515 @default.
- W4323275735 hasVolume "190" @default.
- W4323275735 isParatext "false" @default.
- W4323275735 isRetracted "false" @default.
- W4323275735 workType "article" @default.