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- W4323287320 abstract "A rigorous determination of effector contributions of tumor-infiltrating immune cells is critical for identifying targetable molecular mechanisms for the development of novel cancer immunotherapies. A tumor/immune cell-admixture model is an advantageous strategy to study tumor immunology as the fundamental methodology is relatively straightforward, while also being adaptable to scale to address increasingly complex research queries. Ultimately, this method can provide robust experimental information to complement more traditional murine models of tumor immunology. Here, we describe a tumor/macrophage-admixture model using bone marrow-derived macrophages to investigate macrophage-dependent tumorigenesis. Additionally, we provide commentary on potential branch points for optimization with other immune cells, experimental techniques, and cancer types." @default.
- W4323287320 created "2023-03-07" @default.
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- W4323287320 date "2023-01-01" @default.
- W4323287320 modified "2023-09-26" @default.
- W4323287320 title "A Tumor-admixture Model to Interrogate Immune Cell–dependent Tumorigenesis" @default.
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- W4323287320 doi "https://doi.org/10.21769/bioprotoc.4630" @default.
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