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• W4323306999 abstract "HomeCirculationVol. 147, No. 10Risk of Incident Thromboembolic and Ischemic Events After COVID-19 Vaccination Compared With SARS-CoV-2 Infection No AccessLetterRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessLetterRequest AccessFull TextRisk of Incident Thromboembolic and Ischemic Events After COVID-19 Vaccination Compared With SARS-CoV-2 Infection Mats C. Højbjerg Lassen, MD, Daniel Modin, MB, Kristoffer Grundtvig Skaarup, MD, Niklas Dyrby Johansen, MD, Brian Claggett, MS, PhD, Scott D. Solomon, MD, Michael Fralick, MD, PhD, Jens Ulrik Stæhr Jensen, MD, PhD, Pradeesh Sivapalan, MD, PhD, Muthiah Vaduganathan, MD, MPH, Manan Pareek, MD, PhD, Morten Schou, MD, PhD, Tyra Grove Krause, MD, PhD, Anders Hviid, DMSc, Lars Køber, MD, DMSc, Christian Torp-Pedersen, MD, DMSc, Gunnar Gislason, MD, PhD and Tor Biering-Sørensen, MD, PhD, MPH, MSc Mats C. Højbjerg LassenMats C. Højbjerg Lassen Correspondence to: Mats Christian Højbjerg Lassen, MD, Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Department of Cardiology, Herlev & Gentofte Hospital, University of Copenhagen, Niels Andersens vej 65, 2900 Hellerup, Denmark. Email E-mail Address: [email protected] https://orcid.org/0000-0002-2255-582X Department of Cardiology (M.C.H.L., D.M., K.G.S., N.D.J., M.P., M.S., G.G., T.B.-S.), Copenhagen University Hospital–Herlev & Gentofte, Denmark. Search for more papers by this author , Daniel ModinDaniel Modin https://orcid.org/0000-0002-7566-0519 Department of Cardiology (M.C.H.L., D.M., K.G.S., N.D.J., M.P., M.S., G.G., T.B.-S.), Copenhagen University Hospital–Herlev & Gentofte, Denmark. Search for more papers by this author , Kristoffer Grundtvig SkaarupKristoffer Grundtvig Skaarup https://orcid.org/0000-0002-2690-7511 Department of Cardiology (M.C.H.L., D.M., K.G.S., N.D.J., M.P., M.S., G.G., T.B.-S.), Copenhagen University Hospital–Herlev & Gentofte, Denmark. Search for more papers by this author , Niklas Dyrby JohansenNiklas Dyrby Johansen https://orcid.org/0000-0001-6959-3236 Department of Cardiology (M.C.H.L., D.M., K.G.S., N.D.J., M.P., M.S., G.G., T.B.-S.), Copenhagen University Hospital–Herlev & Gentofte, Denmark. Search for more papers by this author , Brian ClaggettBrian Claggett https://orcid.org/0000-0002-4215-9218 Department of Medicine, Cardiovascular Medicine Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA (B.C., S.D.S., M.V., M.P.). Search for more papers by this author , Scott D. SolomonScott D. Solomon https://orcid.org/0000-0003-3698-9597 Department of Medicine, Cardiovascular Medicine Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA (B.C., S.D.S., M.V., M.P.). Search for more papers by this author , Michael FralickMichael Fralick Sinai Health System and the Department of Medicine, University of Toronto, Canada (M.F.). Search for more papers by this author , Jens Ulrik Stæhr JensenJens Ulrik Stæhr Jensen https://orcid.org/0000-0003-4036-0521 Respiratory Medicine Section, Department of Internal Medicine (J.U.S.J., P.S.), Copenhagen University Hospital–Herlev & Gentofte, Denmark. Department of Clinical Medicine, Faculty of Health Sciences, University of Copenhagen, Denmark (J.U.S.J., G.G.). Search for more papers by this author , Pradeesh SivapalanPradeesh Sivapalan Respiratory Medicine Section, Department of Internal Medicine (J.U.S.J., P.S.), Copenhagen University Hospital–Herlev & Gentofte, Denmark. Search for more papers by this author , Muthiah VaduganathanMuthiah Vaduganathan https://orcid.org/0000-0003-0885-1953 Department of Medicine, Cardiovascular Medicine Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA (B.C., S.D.S., M.V., M.P.). Search for more papers by this author , Manan PareekManan Pareek Department of Cardiology (M.C.H.L., D.M., K.G.S., N.D.J., M.P., M.S., G.G., T.B.-S.), Copenhagen University Hospital–Herlev & Gentofte, Denmark. Department of Medicine, Cardiovascular Medicine Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA (B.C., S.D.S., M.V., M.P.). Search for more papers by this author , Morten SchouMorten Schou https://orcid.org/0000-0002-4271-2466 Department of Cardiology (M.C.H.L., D.M., K.G.S., N.D.J., M.P., M.S., G.G., T.B.-S.), Copenhagen University Hospital–Herlev & Gentofte, Denmark. Search for more papers by this author , Tyra Grove KrauseTyra Grove Krause https://orcid.org/0000-0001-6286-5999 Statens Serum Institut, Copenhagen, Denmark (T.G.K., A.H.). Search for more papers by this author , Anders HviidAnders Hviid https://orcid.org/0000-0002-7509-9127 Statens Serum Institut, Copenhagen, Denmark (T.G.K., A.H.). Pharmacovigilance Research Center, Department of Drug Development and Clinical Pharmacology (A.H.), University of Copenhagen, Denmark. Search for more papers by this author , Lars KøberLars Køber https://orcid.org/0000-0002-6635-1466 Faculty of Health and Medical Sciences, and Department of Cardiology, Copenhagen University Hospital–Rigshospitalet (L.K.), University of Copenhagen, Denmark. Search for more papers by this author , Christian Torp-PedersenChristian Torp-Pedersen https://orcid.org/0000-0003-2892-6131 Department of Cardiology, Copenhagen University Hospital–North Zealand, University of Copenhagen, Hillerød, Denmark (C.T.-P.). Search for more papers by this author , Gunnar GislasonGunnar Gislason https://orcid.org/0000-0002-0548-402X Department of Cardiology (M.C.H.L., D.M., K.G.S., N.D.J., M.P., M.S., G.G., T.B.-S.), Copenhagen University Hospital–Herlev & Gentofte, Denmark. Department of Clinical Medicine, Faculty of Health Sciences, University of Copenhagen, Denmark (J.U.S.J., G.G.). The Danish Heart Foundation, Copenhagen, Denmark (G.G.). The National Institute of Public Health, University of Southern Denmark, Copenhagen (G.G.). Search for more papers by this author and Tor Biering-SørensenTor Biering-Sørensen https://orcid.org/0000-0003-4209-2778 Department of Cardiology (M.C.H.L., D.M., K.G.S., N.D.J., M.P., M.S., G.G., T.B.-S.), Copenhagen University Hospital–Herlev & Gentofte, Denmark. Department of Biomedical Sciences (T.B.-S.), University of Copenhagen, Denmark. Search for more papers by this author Originally published6 Mar 2023https://doi.org/10.1161/CIRCULATIONAHA.122.063296Circulation. 2023;147:843–845FootnotesFor Sources of Funding and Disclosures, see page 844.Circulation is available at www.ahajournals.org/journal/circCorrespondence to: Mats Christian Højbjerg Lassen, MD, Center for Translational Cardiology and Pragmatic Randomized Trials (CTCPR), Department of Cardiology, Herlev & Gentofte Hospital, University of Copenhagen, Niels Andersens vej 65, 2900 Hellerup, Denmark. Email [email protected]dkReferences1. Katsoularis I, Fonseca-Rodríguez O, Farrington P, Lindmark K, Fors Connolly A-M. Risk of acute myocardial infarction and ischaemic stroke following COVID-19 in Sweden: a self-controlled case series and matched cohort study.Lancet. 2021; 398:599–607. doi: 10.1016/s0140-6736(21)00896-5CrossrefMedlineGoogle Scholar2. Modin D, Claggett B, Sindet-Pedersen C, Lassen MCH, Skaarup KG, Jensen JUS, Fralick M, Schou M, Lamberts M, Gerds T, et al. Acute COVID-19 and the incidence of ischemic stroke and acute myocardial infarction.Circulation. 2020; 142:2080–2082. doi: 10.1161/CIRCULATIONAHA.120.050809LinkGoogle Scholar3. Hippisley-Cox J, Patone M, Mei XW, Saatci D, Dixon S, Khunti K, Zaccardi F, Watkinson P, Shankar-Hari M, Doidge J, et al. Risk of thrombocytopenia and thromboembolism after covid-19 vaccination and SARS-CoV-2 positive testing: self-controlled case series study.BMJ. 2021; 374:n1931. doi: 10.1136/bmj.n1931CrossrefMedlineGoogle Scholar4. Andrews NJ, Stowe J, Ramsay ME, Miller E. Risk of venous thrombotic events and thrombocytopenia in sequential time periods after ChAdOx1 and BNT162b2 COVID-19 vaccines: A national cohort study in England.Lancet Reg Health Eur. 2022; 13:100260. doi: 10.1016/j.lanepe.2021.100260CrossrefMedlineGoogle Scholar5. Simpson CR, Shi T, Vasileiou E, Katikireddi SV, Kerr S, Moore E, McCowan C, Agrawal U, Shah SA, Ritchie LD, et al. First-dose ChAdOx1 and BNT162b2 COVID-19 vaccines and thrombocytopenic, thromboembolic and hemorrhagic events in Scotland.Nat Med. 2021; 27:1290–1297. doi: 10.1038/s41591-021-01408-4CrossrefMedlineGoogle Scholar Previous Back to top Next FiguresReferencesRelatedDetails March 7, 2023Vol 147, Issue 10 Advertisement Article InformationMetrics © 2023 American Heart Association, Inc.https://doi.org/10.1161/CIRCULATIONAHA.122.063296PMID: 36877771 Originally publishedMarch 6, 2023 KeywordsvaccinesCOVID-19SARS-CoV-2PDF download Advertisement SubjectsEpidemiology" @default.
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