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- W4323308744 abstract "Abstract To determine relationship between physical comorbidity (PC) and depression in Korean adults’ cancer survivors and understand if non-exercise estimation of cardiorespiratory fitness (eCRF) might have a mediating effect on such relationship. Data of 448 cancer survivors aged 20–64 years old in Korean National Health and Nutrition Examination Survey Ⅶ-Ⅷ (2016–2020) were analyzed. Depression was assessed with a 9-item Patient Health Questionnaire (PHQ-9). Subjects were categorized into two groups: normal and depression. PC was defined if a participant was diagnosed by a physician or was being treated at the time of the survey. eCRF was determined with sex and age-specific algorithms. In the mediation model, PC (β = 1.836, 95%CI: 1.577 to 2.095, p < 0.001) was significantly association with depression and eCRF levels mediated (indirect effect = 0.094, bootstrap 95%CI: 0.028 to 0.146) this association. Mediation analysis showed a significant, direct, and indirect effect with a significant Sobel test value (z = 2.517, p = 0.011). The relationship between PC and depression was significantly mediated by eCRF levels. Early physical activity interventions might prevent depression in cancer survivors with chronic diseases." @default.
- W4323308744 created "2023-03-07" @default.
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- W4323308744 date "2023-03-07" @default.
- W4323308744 modified "2023-10-18" @default.
- W4323308744 title "Mediating Effect of Non-Exercise Estimation of Cardiorespiratory Fitness on Relationship Between Physical Comorbidity and Depression in Korean Adult Cancer Survivors" @default.
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- W4323308744 doi "https://doi.org/10.21203/rs.3.rs-2618337/v1" @default.
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