Matches in SemOpenAlex for { <https://semopenalex.org/work/W4323355963> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W4323355963 endingPage "52" @default.
- W4323355963 startingPage "45" @default.
- W4323355963 abstract "Background: The availability of the COVID-19 vaccine during the pandemic has changed the disease course in the entire world. The current study aimed to compare various hematological parameters among COVID-19 patients with and without vaccination. Methods: The present retrospective study included 26 vaccinated and 26 non-vaccinated COVID-19 patients. Various clinical and biochemical parameters of RT-PCR-positive patients were collected. The values are expressed in Mean±SD or median values IQR. Mann-Whitney U test was used for comparison between the groups. Results: Among the vaccinated individuals, 17 cases (65.4%) were asymptomatic, one patient (3.8%) had moderate, eight cases (30.8%) had mild COVID-19 infection and all 26 patients were completely recovered. Among non-vaccinated COVID-19 patients, 25 cases (96.2%) had severe, one case (3.8%) had moderate COVID-19, and 16 patients (61.5%) recovered but ten cases succumbed to COVID-19. There were statistically significant differences in SpO2, total leucocyte count, and differential counts of neutrophils, lymphocytes, eosinophils, monocytes, and basophils between vaccinated and non-vaccinated patients (P<0.001). The neutrophil/lymphocyte ratio was found to be at a higher level (P<0.01) among non-vaccinated patients [10.9(4.28-23.63)] compared to vaccinated [1.55(1.09-2.28)]. The blood urea, total and direct bilirubin, serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), and inflammatory markers, like C-reactive protein (CRP), D-dimer, ferritin, and lactate dehydrogenase (LDH) were highly elevated in non-vaccinated patients (P<0.001). Moreover, lower values of total protein, serum albumin, and albumin and globulin (A/G) ratio were noted in the non-vaccinated compared to vaccinated individuals (P<0.001). Conclusion: Vaccinated patients had milder disease with fewer derangements of hematological parameters compared to non-vaccinated patients. It can be concluded that vaccine has played a vital role during the COVID-19 pandemic in reducing mortality." @default.
- W4323355963 created "2023-03-08" @default.
- W4323355963 creator A5012621623 @default.
- W4323355963 creator A5057977829 @default.
- W4323355963 creator A5064342581 @default.
- W4323355963 creator A5088397178 @default.
- W4323355963 date "2023-03-07" @default.
- W4323355963 modified "2023-09-30" @default.
- W4323355963 title "Comparison of Biochemical and Hematological Parameters Among COVID-19 Patients With and Without Vaccination in a Tertiary Care Hospital: A Retrospective" @default.
- W4323355963 doi "https://doi.org/10.32598/pbr.9.1.1094.1" @default.
- W4323355963 hasPublicationYear "2023" @default.
- W4323355963 type Work @default.
- W4323355963 citedByCount "0" @default.
- W4323355963 crossrefType "journal-article" @default.
- W4323355963 hasAuthorship W4323355963A5012621623 @default.
- W4323355963 hasAuthorship W4323355963A5057977829 @default.
- W4323355963 hasAuthorship W4323355963A5064342581 @default.
- W4323355963 hasAuthorship W4323355963A5088397178 @default.
- W4323355963 hasBestOaLocation W43233559631 @default.
- W4323355963 hasConcept C126322002 @default.
- W4323355963 hasConcept C167135981 @default.
- W4323355963 hasConcept C181199279 @default.
- W4323355963 hasConcept C203014093 @default.
- W4323355963 hasConcept C22070199 @default.
- W4323355963 hasConcept C2776877979 @default.
- W4323355963 hasConcept C2777318727 @default.
- W4323355963 hasConcept C2777513400 @default.
- W4323355963 hasConcept C2777761686 @default.
- W4323355963 hasConcept C2777910003 @default.
- W4323355963 hasConcept C2778319317 @default.
- W4323355963 hasConcept C2778606649 @default.
- W4323355963 hasConcept C55493867 @default.
- W4323355963 hasConcept C71924100 @default.
- W4323355963 hasConcept C86803240 @default.
- W4323355963 hasConcept C90924648 @default.
- W4323355963 hasConceptScore W4323355963C126322002 @default.
- W4323355963 hasConceptScore W4323355963C167135981 @default.
- W4323355963 hasConceptScore W4323355963C181199279 @default.
- W4323355963 hasConceptScore W4323355963C203014093 @default.
- W4323355963 hasConceptScore W4323355963C22070199 @default.
- W4323355963 hasConceptScore W4323355963C2776877979 @default.
- W4323355963 hasConceptScore W4323355963C2777318727 @default.
- W4323355963 hasConceptScore W4323355963C2777513400 @default.
- W4323355963 hasConceptScore W4323355963C2777761686 @default.
- W4323355963 hasConceptScore W4323355963C2777910003 @default.
- W4323355963 hasConceptScore W4323355963C2778319317 @default.
- W4323355963 hasConceptScore W4323355963C2778606649 @default.
- W4323355963 hasConceptScore W4323355963C55493867 @default.
- W4323355963 hasConceptScore W4323355963C71924100 @default.
- W4323355963 hasConceptScore W4323355963C86803240 @default.
- W4323355963 hasConceptScore W4323355963C90924648 @default.
- W4323355963 hasIssue "1" @default.
- W4323355963 hasLocation W43233559631 @default.
- W4323355963 hasOpenAccess W4323355963 @default.
- W4323355963 hasPrimaryLocation W43233559631 @default.
- W4323355963 hasRelatedWork W1994857449 @default.
- W4323355963 hasRelatedWork W2137513274 @default.
- W4323355963 hasRelatedWork W2349624551 @default.
- W4323355963 hasRelatedWork W2380048095 @default.
- W4323355963 hasRelatedWork W2407268464 @default.
- W4323355963 hasRelatedWork W2411847911 @default.
- W4323355963 hasRelatedWork W2912327950 @default.
- W4323355963 hasRelatedWork W3172771122 @default.
- W4323355963 hasRelatedWork W3204839202 @default.
- W4323355963 hasRelatedWork W2188311784 @default.
- W4323355963 hasVolume "9" @default.
- W4323355963 isParatext "false" @default.
- W4323355963 isRetracted "false" @default.
- W4323355963 workType "article" @default.