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• W4323538002 abstract "Abstract Background Fear of firework noises and other loud, sudden noises (noise reactivity) is a significant problem for many dogs and may have a negative effect on both welfare and, in severe cases, the life expectancy of dogs. A wide range of behavior traits, including fear-related behaviors, have high heritability estimates in dogs. The aim of this study was to estimate genomic heritability for fear of fireworks and loud noises in dogs. Results A genomic heritability estimate was performed based on genome-wide SNPs from standard poodles with records of fear of fireworks and noise reactivity. The study was based on questionnaires answered by owners, who also volunteered to return a cheek swab from their dog for DNA analyses. SNP-based heritability was estimated to be 0.28 for firework fear and 0.16 for noise reactivity. We also identified an interesting region on chromosome 17 that was weakly associated with both traits. Conclusions We have estimated low to medium genomic heritabilities for fear of fireworks and noise reactivity in standard poodles. We have also identified an interesting region on chromosome 17, which harbors genes that have been shown to be involved in different psychiatric traits with anxiety components in humans. The region was associated with both traits; however, the association was weak and need further verification from other studies." @default.
• W4323538002 created "2023-03-09" @default.
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• W4323538002 date "2023-03-08" @default.
• W4323538002 modified "2023-10-10" @default.
• W4323538002 title "Genomic analysis of firework fear and noise reactivity in standard poodles" @default.
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• W4323538002 doi "https://doi.org/10.1186/s40575-023-00125-0" @default.
• W4323538002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36890545" @default.
• W4323538002 hasPublicationYear "2023" @default.
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