Matches in SemOpenAlex for { <https://semopenalex.org/work/W4323655385> ?p ?o ?g. }
- W4323655385 abstract "Introduction Bacteria are the most common pathogens implicated in ascending infections in patients with cervical insufficiency. However, Candida albicans is a rare and serious cause of intra-amniotic infection that should be considered on the differential diagnosis. Upon diagnosis following cerclage placement, patients are generally advised to undergo immediate cerclage removal and discontinuation of the pregnancy due to the high risk of maternal and fetal morbidity. However, some patients decline and instead elect to continue the pregnancy with or without treatment. Limited data exist to guide management of these high-risk patients. Case Presentation We describe a case of previable intra-amniotic C. albicans infection diagnosed following physical examination–indicated cerclage placement. The patient declined pregnancy termination and subsequently underwent systemic antifungal therapy as well as serial intra-amniotic fluconazole instillations. Fetal blood sampling confirmed transplacental transfer of maternal systemic antifungal therapy. The fetus delivered preterm and without evidence of fungemia, despite persistently positive amniotic fluid cultures. Conclusion In a well-counseled patient with culture-proven intra-amniotic C. albicans infection declining termination of pregnancy, multimodal antifungal therapy in the form of systemic and intra-amniotic fluconazole administration may prevent subsequent fetal or neonatal fungemia and improve postnatal outcomes. Key Points" @default.
- W4323655385 created "2023-03-10" @default.
- W4323655385 creator A5005927011 @default.
- W4323655385 creator A5025241976 @default.
- W4323655385 creator A5026940269 @default.
- W4323655385 creator A5040533647 @default.
- W4323655385 creator A5085943579 @default.
- W4323655385 date "2023-03-09" @default.
- W4323655385 modified "2023-10-16" @default.
- W4323655385 title "Multimodal Management of Cervical Insufficiency Complicated by Intra-amniotic Candida albicans Infection" @default.
- W4323655385 cites W1772600734 @default.
- W4323655385 cites W1833375220 @default.
- W4323655385 cites W1994951476 @default.
- W4323655385 cites W2005071815 @default.
- W4323655385 cites W2019393533 @default.
- W4323655385 cites W2049196341 @default.
- W4323655385 cites W2053680743 @default.
- W4323655385 cites W2090757258 @default.
- W4323655385 cites W2141117389 @default.
- W4323655385 cites W2159102406 @default.
- W4323655385 cites W2185209312 @default.
- W4323655385 cites W2223965459 @default.
- W4323655385 cites W2403477753 @default.
- W4323655385 cites W2571079870 @default.
- W4323655385 cites W2767006851 @default.
- W4323655385 cites W2924328639 @default.
- W4323655385 cites W2954108466 @default.
- W4323655385 cites W3036012418 @default.
- W4323655385 cites W3044860898 @default.
- W4323655385 cites W3112229579 @default.
- W4323655385 cites W3163548177 @default.
- W4323655385 cites W4235911572 @default.
- W4323655385 cites W4250522809 @default.
- W4323655385 cites W85752698 @default.
- W4323655385 doi "https://doi.org/10.1055/a-2051-2353" @default.
- W4323655385 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36894156" @default.
- W4323655385 hasPublicationYear "2023" @default.
- W4323655385 type Work @default.
- W4323655385 citedByCount "0" @default.
- W4323655385 crossrefType "journal-article" @default.
- W4323655385 hasAuthorship W4323655385A5005927011 @default.
- W4323655385 hasAuthorship W4323655385A5025241976 @default.
- W4323655385 hasAuthorship W4323655385A5026940269 @default.
- W4323655385 hasAuthorship W4323655385A5040533647 @default.
- W4323655385 hasAuthorship W4323655385A5085943579 @default.
- W4323655385 hasConcept C121608353 @default.
- W4323655385 hasConcept C126322002 @default.
- W4323655385 hasConcept C131872663 @default.
- W4323655385 hasConcept C141071460 @default.
- W4323655385 hasConcept C16005928 @default.
- W4323655385 hasConcept C172680121 @default.
- W4323655385 hasConcept C2777740455 @default.
- W4323655385 hasConcept C2778194526 @default.
- W4323655385 hasConcept C2778715236 @default.
- W4323655385 hasConcept C2779234561 @default.
- W4323655385 hasConcept C2779508502 @default.
- W4323655385 hasConcept C2779548794 @default.
- W4323655385 hasConcept C2780558435 @default.
- W4323655385 hasConcept C2780651595 @default.
- W4323655385 hasConcept C2780908437 @default.
- W4323655385 hasConcept C2780917455 @default.
- W4323655385 hasConcept C2910530332 @default.
- W4323655385 hasConcept C46973012 @default.
- W4323655385 hasConcept C54355233 @default.
- W4323655385 hasConcept C71924100 @default.
- W4323655385 hasConcept C86803240 @default.
- W4323655385 hasConceptScore W4323655385C121608353 @default.
- W4323655385 hasConceptScore W4323655385C126322002 @default.
- W4323655385 hasConceptScore W4323655385C131872663 @default.
- W4323655385 hasConceptScore W4323655385C141071460 @default.
- W4323655385 hasConceptScore W4323655385C16005928 @default.
- W4323655385 hasConceptScore W4323655385C172680121 @default.
- W4323655385 hasConceptScore W4323655385C2777740455 @default.
- W4323655385 hasConceptScore W4323655385C2778194526 @default.
- W4323655385 hasConceptScore W4323655385C2778715236 @default.
- W4323655385 hasConceptScore W4323655385C2779234561 @default.
- W4323655385 hasConceptScore W4323655385C2779508502 @default.
- W4323655385 hasConceptScore W4323655385C2779548794 @default.
- W4323655385 hasConceptScore W4323655385C2780558435 @default.
- W4323655385 hasConceptScore W4323655385C2780651595 @default.
- W4323655385 hasConceptScore W4323655385C2780908437 @default.
- W4323655385 hasConceptScore W4323655385C2780917455 @default.
- W4323655385 hasConceptScore W4323655385C2910530332 @default.
- W4323655385 hasConceptScore W4323655385C46973012 @default.
- W4323655385 hasConceptScore W4323655385C54355233 @default.
- W4323655385 hasConceptScore W4323655385C71924100 @default.
- W4323655385 hasConceptScore W4323655385C86803240 @default.
- W4323655385 hasLocation W43236553851 @default.
- W4323655385 hasLocation W43236553852 @default.
- W4323655385 hasOpenAccess W4323655385 @default.
- W4323655385 hasPrimaryLocation W43236553851 @default.
- W4323655385 hasRelatedWork W121520884 @default.
- W4323655385 hasRelatedWork W2047906947 @default.
- W4323655385 hasRelatedWork W2048296713 @default.
- W4323655385 hasRelatedWork W2056752164 @default.
- W4323655385 hasRelatedWork W2069854999 @default.
- W4323655385 hasRelatedWork W2322060503 @default.
- W4323655385 hasRelatedWork W2461546254 @default.
- W4323655385 hasRelatedWork W3088570978 @default.
- W4323655385 hasRelatedWork W3131399687 @default.