Matches in SemOpenAlex for { <https://semopenalex.org/work/W4323664863> ?p ?o ?g. }
- W4323664863 endingPage "5208" @default.
- W4323664863 startingPage "5208" @default.
- W4323664863 abstract "Breast cancer (BC) continues to be the most diagnosed tumor in women and a very heterogeneous disease both inter- and intratumoral, mainly given by the variety of molecular profiles with different biological and clinical characteristics. Despite the advancements in early detection and therapeutic strategies, the survival rate is low in patients who develop metastatic disease. Therefore, it is mandatory to explore new approaches to achieve better responses. In this regard, immunotherapy arose as a promising alternative to conventional treatments due to its ability to modulate the immune system, which may play a dual role in this disease since the relationship between the immune system and BC cells depends on several factors: the tumor histology and size, as well as the involvement of lymph nodes, immune cells, and molecules that are part of the tumor microenvironment. Particularly, myeloid-derived suppressor cell (MDSC) expansion is one of the major immunosuppressive mechanisms used by breast tumors since it has been associated with worse clinical stage, metastatic burden, and poor efficacy of immunotherapies. This review focuses on the new immunotherapies in BC in the last five years. Additionally, the role of MDSC as a therapeutic target in breast cancer will be described." @default.
- W4323664863 created "2023-03-10" @default.
- W4323664863 creator A5008908552 @default.
- W4323664863 creator A5010454411 @default.
- W4323664863 creator A5012709103 @default.
- W4323664863 creator A5026985874 @default.
- W4323664863 creator A5032006767 @default.
- W4323664863 creator A5038461805 @default.
- W4323664863 creator A5038554573 @default.
- W4323664863 creator A5041427835 @default.
- W4323664863 date "2023-03-08" @default.
- W4323664863 modified "2023-10-18" @default.
- W4323664863 title "Defining the Emergence of New Immunotherapy Approaches in Breast Cancer: Role of Myeloid-Derived Suppressor Cells" @default.
- W4323664863 cites W1488814076 @default.
- W4323664863 cites W1573328063 @default.
- W4323664863 cites W1587782817 @default.
- W4323664863 cites W1610624614 @default.
- W4323664863 cites W1769686661 @default.
- W4323664863 cites W1775915307 @default.
- W4323664863 cites W1805817493 @default.
- W4323664863 cites W1881296535 @default.
- W4323664863 cites W1893818399 @default.
- W4323664863 cites W1931089671 @default.
- W4323664863 cites W1970708694 @default.
- W4323664863 cites W1976705588 @default.
- W4323664863 cites W1991646010 @default.
- W4323664863 cites W1992029528 @default.
- W4323664863 cites W1996145004 @default.
- W4323664863 cites W1996814108 @default.
- W4323664863 cites W2000971601 @default.
- W4323664863 cites W2004150448 @default.
- W4323664863 cites W2006710185 @default.
- W4323664863 cites W2015544847 @default.
- W4323664863 cites W2015776459 @default.
- W4323664863 cites W2019214729 @default.
- W4323664863 cites W2033577259 @default.
- W4323664863 cites W2036013383 @default.
- W4323664863 cites W2038632547 @default.
- W4323664863 cites W2039183048 @default.
- W4323664863 cites W2046808766 @default.
- W4323664863 cites W2051998002 @default.
- W4323664863 cites W2052400191 @default.
- W4323664863 cites W2054732723 @default.
- W4323664863 cites W2058648826 @default.
- W4323664863 cites W2062398277 @default.
- W4323664863 cites W2068386288 @default.
- W4323664863 cites W2071033172 @default.
- W4323664863 cites W2073464835 @default.
- W4323664863 cites W2075531452 @default.
- W4323664863 cites W2076777479 @default.
- W4323664863 cites W2095911832 @default.
- W4323664863 cites W2096600293 @default.
- W4323664863 cites W2096833042 @default.
- W4323664863 cites W2099842692 @default.
- W4323664863 cites W2102144390 @default.
- W4323664863 cites W2102718441 @default.
- W4323664863 cites W2104450327 @default.
- W4323664863 cites W2105871790 @default.
- W4323664863 cites W2110727184 @default.
- W4323664863 cites W2113735973 @default.
- W4323664863 cites W2117692326 @default.
- W4323664863 cites W2120431466 @default.
- W4323664863 cites W2125200037 @default.
- W4323664863 cites W2128577473 @default.
- W4323664863 cites W2129508578 @default.
- W4323664863 cites W2132853354 @default.
- W4323664863 cites W2134338732 @default.
- W4323664863 cites W2134539328 @default.
- W4323664863 cites W2137158234 @default.
- W4323664863 cites W2140747721 @default.
- W4323664863 cites W2141414987 @default.
- W4323664863 cites W2141935247 @default.
- W4323664863 cites W2144577255 @default.
- W4323664863 cites W2145067668 @default.
- W4323664863 cites W2145136557 @default.
- W4323664863 cites W2153646261 @default.
- W4323664863 cites W2154041075 @default.
- W4323664863 cites W2155463462 @default.
- W4323664863 cites W2157269800 @default.
- W4323664863 cites W2161859910 @default.
- W4323664863 cites W2165537599 @default.
- W4323664863 cites W2166784282 @default.
- W4323664863 cites W2167121370 @default.
- W4323664863 cites W2167129525 @default.
- W4323664863 cites W2171481006 @default.
- W4323664863 cites W2177327503 @default.
- W4323664863 cites W2276265267 @default.
- W4323664863 cites W2290107239 @default.
- W4323664863 cites W2328399718 @default.
- W4323664863 cites W2334682805 @default.
- W4323664863 cites W2343453190 @default.
- W4323664863 cites W2402636472 @default.
- W4323664863 cites W2407664560 @default.
- W4323664863 cites W2442621493 @default.
- W4323664863 cites W2471500324 @default.
- W4323664863 cites W2515482312 @default.
- W4323664863 cites W2527549654 @default.
- W4323664863 cites W2530700542 @default.