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• W4323804942 endingPage "e0273446" @default.
• W4323804942 startingPage "e0273446" @default.
• W4323804942 abstract "Muscle segmentation is a process relied upon to gather medical image-based muscle characterisation, useful in directly assessing muscle volume and geometry, that can be used as inputs to musculoskeletal modelling pipelines. Manual or semi-automatic techniques are typically employed to segment the muscles and quantify their properties, but they require significant manual labour and incur operator repeatability issues. In this study an automatic process is presented, aiming to segment all lower limb muscles from Magnetic Resonance (MR) imaging data simultaneously using three-dimensional (3D) deformable image registration (single inputs or multi-atlas). Twenty-three of the major lower limb skeletal muscles were segmented from five subjects, with an average Dice similarity coefficient of 0.72, and average absolute relative volume error (RVE) of 12.7% (average relative volume error of -2.2%) considering the optimal subject combinations. The multi-atlas approach showed slightly better accuracy (average DSC: 0.73; average RVE: 1.67%). Segmented MR imaging datasets of the lower limb are not widely available in the literature, limiting the potential of new, probabilistic methods such as deep learning to be used in the context of muscle segmentation. In this work, Non-linear deformable image registration is used to generate 69 manually checked, segmented, 3D, artificial datasets, allowing access for future studies to use these new methods, with a large amount of reliable reference data." @default.
• W4323804942 created "2023-03-11" @default.
• W4323804942 creator A5048644893 @default.
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• W4323804942 date "2023-03-10" @default.
• W4323804942 modified "2023-10-16" @default.
• W4323804942 title "Deformable image registration based on single or multi-atlas methods for automatic muscle segmentation and the generation of augmented imaging datasets" @default.
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• W4323804942 doi "https://doi.org/10.1371/journal.pone.0273446" @default.
• W4323804942 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36897869" @default.
• W4323804942 hasPublicationYear "2023" @default.
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