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- W4323817131 endingPage "106384" @default.
- W4323817131 startingPage "106384" @default.
- W4323817131 abstract "A set of highly connected brain regions called the rich-club are vital in integrating information across the functional connectome. Although the literature has identified some changes in rich-club organization with age, little is known about potential sex-specific developmental trajectories, and neurophysiologically relevant frequency-dependent changes have not been established. Here we examine the frequency- and sex-dependent development of rich-club organization using magnetoencephalography in a large normative sample (N = 383) over a wide age span (4-39 years). We report strong divergence between males and females across alpha, beta, and gamma frequencies. While males show increased or no change in rich-club organization with age, females show a consistent, non-linear trajectory that increases through childhood, shifting direction in early adolescence. Using neurophysiological modalities for capturing complex inter-relations between oscillatory dynamics, age, and sex, we establish diverging, sex-specific developmental trajectories of the brain's core functional organization, critically important to our understanding of brain health and disease." @default.
- W4323817131 created "2023-03-11" @default.
- W4323817131 creator A5002960846 @default.
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- W4323817131 creator A5054476201 @default.
- W4323817131 creator A5062242356 @default.
- W4323817131 creator A5075931556 @default.
- W4323817131 date "2023-04-01" @default.
- W4323817131 modified "2023-10-17" @default.
- W4323817131 title "Richer than we thought: neurophysiological methods reveal rich-club network development is frequency- and sex-dependent" @default.
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