FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4323827663> ?p ?o ?g. }

• W4323827663 abstract "Abstract Background Adherence to antiretroviral (ARV) treatment for HIV infection is challenging because of many factors. The World Health Organization (WHO) has recommended using digital adherence technologies (DATs). However, there is limited evidence on how DATs improve adherence. Wisepill® is an internet enable medication dispenser found feasible and acceptable in several studies. However, limited evidence is available on its effectiveness in improving ART adherence, specifically among children and adolescents. Furthermore, DATs are often developed without involving the target groups. We propose a two-stage project consisting of a formative study to customize an existing Wisepill DAT intervention and a randomized clinical trial, to investigate the effectiveness of DAT combined with reminder cues and tailored feedback on adherence to ARV treatment among children and adolescents living with HIV and retention in care among breastfeeding women living with HIV in Kilimanjaro and Arusha Region, Tanzania. Methods We will conduct a formative study mixed-methods study and three sub-trials in Kilimanjaro and Arusha Regions among (1) children aged 0–14 years and their caregivers, (2) adolescents aged 15–19 years and (3) breastfeeding women and their HIV-negative infants. In the formative study, we will collect and analyse data on needs and contents for DATs, including the contents of short message service (SMS) texts and tailored feedback. The results will inform the customization of the DAT to be tested in the sub-trials. In the trials, participants will be randomized in the intervention arm, where the DAT will be implemented or the control arm, where standard care will be followed. Participants in the intervention arm will take their medication from the Wisepill-box and receive daily reminder texts and tailored feedback during clinic visits. Discussion If the intervention improves adherence to ART and the devices are acceptable, accurate and sustainable, the intervention can be scaled up within the National Aids Control Programmes. Trial registration: PACTR202301844164954, date 27 January 2023" @default.
• W4323827663 created "2023-03-11" @default.
• W4323827663 creator A5009802278 @default.
• W4323827663 creator A5022537757 @default.
• W4323827663 creator A5022705713 @default.
• W4323827663 creator A5028870626 @default.
• W4323827663 creator A5031242719 @default.
• W4323827663 creator A5057762903 @default.
• W4323827663 creator A5061382446 @default.
• W4323827663 creator A5065981875 @default.
• W4323827663 creator A5078789624 @default.
• W4323827663 creator A5085919150 @default.
• W4323827663 creator A5088731531 @default.
• W4323827663 date "2023-03-10" @default.
• W4323827663 modified "2023-10-18" @default.
• W4323827663 title "Effect of a customized digital adherence tool on retention in care and adherence to antiretroviral treatment in breastfeeding women, children and adolescents living with HIV in Tanzania: a mixed-methods study followed by clinical trials" @default.
• W4323827663 cites W1751241479 @default.
• W4323827663 cites W1982612158 @default.
• W4323827663 cites W2017547390 @default.
• W4323827663 cites W2072428858 @default.
• W4323827663 cites W2109168061 @default.
• W4323827663 cites W2173188384 @default.
• W4323827663 cites W2275808657 @default.
• W4323827663 cites W2317877902 @default.
• W4323827663 cites W2319207928 @default.
• W4323827663 cites W2465631293 @default.
• W4323827663 cites W2476260174 @default.
• W4323827663 cites W2554116060 @default.
• W4323827663 cites W2606731845 @default.
• W4323827663 cites W2614092991 @default.
• W4323827663 cites W2777019505 @default.
• W4323827663 cites W2782224226 @default.
• W4323827663 cites W2782929822 @default.
• W4323827663 cites W2790398503 @default.
• W4323827663 cites W2790876886 @default.
• W4323827663 cites W2803594112 @default.
• W4323827663 cites W2809104089 @default.
• W4323827663 cites W2897270423 @default.
• W4323827663 cites W2924249028 @default.
• W4323827663 cites W2966690745 @default.
• W4323827663 cites W3007268652 @default.
• W4323827663 cites W3135507739 @default.
• W4323827663 cites W3156691340 @default.
• W4323827663 doi "https://doi.org/10.21203/rs.3.rs-2604485/v1" @default.
• W4323827663 hasPublicationYear "2023" @default.
• W4323827663 type Work @default.
• W4323827663 citedByCount "0" @default.
• W4323827663 crossrefType "posted-content" @default.
• W4323827663 hasAuthorship W4323827663A5009802278 @default.
• W4323827663 hasAuthorship W4323827663A5022537757 @default.
• W4323827663 hasAuthorship W4323827663A5022705713 @default.
• W4323827663 hasAuthorship W4323827663A5028870626 @default.
• W4323827663 hasAuthorship W4323827663A5031242719 @default.
• W4323827663 hasAuthorship W4323827663A5057762903 @default.
• W4323827663 hasAuthorship W4323827663A5061382446 @default.
• W4323827663 hasAuthorship W4323827663A5065981875 @default.
• W4323827663 hasAuthorship W4323827663A5078789624 @default.
• W4323827663 hasAuthorship W4323827663A5085919150 @default.
• W4323827663 hasAuthorship W4323827663A5088731531 @default.
• W4323827663 hasBestOaLocation W43238276631 @default.
• W4323827663 hasConcept C111919701 @default.
• W4323827663 hasConcept C126322002 @default.
• W4323827663 hasConcept C15744967 @default.
• W4323827663 hasConcept C159110408 @default.
• W4323827663 hasConcept C168563851 @default.
• W4323827663 hasConcept C187212893 @default.
• W4323827663 hasConcept C19417346 @default.
• W4323827663 hasConcept C2776283161 @default.
• W4323827663 hasConcept C2779357621 @default.
• W4323827663 hasConcept C2780665704 @default.
• W4323827663 hasConcept C3013748606 @default.
• W4323827663 hasConcept C39432304 @default.
• W4323827663 hasConcept C41008148 @default.
• W4323827663 hasConcept C42525527 @default.
• W4323827663 hasConcept C512399662 @default.
• W4323827663 hasConcept C535046627 @default.
• W4323827663 hasConcept C71924100 @default.
• W4323827663 hasConcept C74558129 @default.
• W4323827663 hasConcept C91375879 @default.
• W4323827663 hasConceptScore W4323827663C111919701 @default.
• W4323827663 hasConceptScore W4323827663C126322002 @default.
• W4323827663 hasConceptScore W4323827663C15744967 @default.
• W4323827663 hasConceptScore W4323827663C159110408 @default.
• W4323827663 hasConceptScore W4323827663C168563851 @default.
• W4323827663 hasConceptScore W4323827663C187212893 @default.
• W4323827663 hasConceptScore W4323827663C19417346 @default.
• W4323827663 hasConceptScore W4323827663C2776283161 @default.
• W4323827663 hasConceptScore W4323827663C2779357621 @default.
• W4323827663 hasConceptScore W4323827663C2780665704 @default.
• W4323827663 hasConceptScore W4323827663C3013748606 @default.
• W4323827663 hasConceptScore W4323827663C39432304 @default.
• W4323827663 hasConceptScore W4323827663C41008148 @default.
• W4323827663 hasConceptScore W4323827663C42525527 @default.
• W4323827663 hasConceptScore W4323827663C512399662 @default.
• W4323827663 hasConceptScore W4323827663C535046627 @default.
• W4323827663 hasConceptScore W4323827663C71924100 @default.
• W4323827663 hasConceptScore W4323827663C74558129 @default.
• W4323827663 hasConceptScore W4323827663C91375879 @default.
• W4323827663 hasLocation W43238276631 @default.
• W4323827663 hasLocation W43238276632 @default.

• next