FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4323830381> ?p ?o ?g. }

• W4323830381 endingPage "1248" @default.
• W4323830381 startingPage "1242" @default.
• W4323830381 abstract "Background Heterotopic ossification is a frequent complication following surgical treatment of elbow trauma. The use of indomethacin to prevent heterotopic ossification is reported in the literature; however, its effectiveness is controversial. The purpose of this randomized, double-blind, placebo-controlled study was to determine whether indomethacin is effective in reducing the incidence and severity of heterotopic ossification after surgical management of elbow trauma. Methods Between February 2013 and April 2018, 164 eligible patients were randomized to receive postoperative indomethacin or placebo medication. The primary outcome was the incidence of heterotopic ossification on elbow radiographs at 1-year follow-up. Secondary outcomes included the Patient Rated Elbow Evaluation score, Mayo Elbow Performance Index score, and Disabilities of the Arm, Shoulder and Hand score. Range of motion, complications, and nonunion rates were also obtained. Results At 1-year follow-up, there was no significant difference in the incidence of heterotopic ossification between the indomethacin group (49%) and the control group (55%) (relative risk, 0.89; P = .52). There were no significant differences in postoperative Patient Rated Elbow Evaluation, Mayo Elbow Performance Index, and Disabilities of the Arm, Shoulder and Hand scores or range of motion (P = .16). The complication rate was 17% in both the treatment and control groups (P > .99). There were no nonunions in either group. Conclusion This Level I study demonstrated that indomethacin prophylaxis against heterotopic ossification in the setting of surgically treated elbow trauma was not significantly different from placebo. Heterotopic ossification is a frequent complication following surgical treatment of elbow trauma. The use of indomethacin to prevent heterotopic ossification is reported in the literature; however, its effectiveness is controversial. The purpose of this randomized, double-blind, placebo-controlled study was to determine whether indomethacin is effective in reducing the incidence and severity of heterotopic ossification after surgical management of elbow trauma. Between February 2013 and April 2018, 164 eligible patients were randomized to receive postoperative indomethacin or placebo medication. The primary outcome was the incidence of heterotopic ossification on elbow radiographs at 1-year follow-up. Secondary outcomes included the Patient Rated Elbow Evaluation score, Mayo Elbow Performance Index score, and Disabilities of the Arm, Shoulder and Hand score. Range of motion, complications, and nonunion rates were also obtained. At 1-year follow-up, there was no significant difference in the incidence of heterotopic ossification between the indomethacin group (49%) and the control group (55%) (relative risk, 0.89; P = .52). There were no significant differences in postoperative Patient Rated Elbow Evaluation, Mayo Elbow Performance Index, and Disabilities of the Arm, Shoulder and Hand scores or range of motion (P = .16). The complication rate was 17% in both the treatment and control groups (P > .99). There were no nonunions in either group. This Level I study demonstrated that indomethacin prophylaxis against heterotopic ossification in the setting of surgically treated elbow trauma was not significantly different from placebo." @default.
• W4323830381 created "2023-03-11" @default.
• W4323830381 creator A5043937771 @default.
• W4323830381 creator A5050130174 @default.
• W4323830381 creator A5074392564 @default.
• W4323830381 creator A5079130465 @default.
• W4323830381 creator A5084393145 @default.
• W4323830381 creator A5085053259 @default.
• W4323830381 date "2023-06-01" @default.
• W4323830381 modified "2023-10-16" @default.
• W4323830381 title "Indomethacin for heterotopic ossification prophylaxis following surgical treatment of elbow trauma: a randomized controlled trial" @default.
• W4323830381 cites W1634439902 @default.
• W4323830381 cites W1964474592 @default.
• W4323830381 cites W1974884549 @default.
• W4323830381 cites W1980880695 @default.
• W4323830381 cites W1981881451 @default.
• W4323830381 cites W1995031048 @default.
• W4323830381 cites W1998752408 @default.
• W4323830381 cites W2002049826 @default.
• W4323830381 cites W2008915544 @default.
• W4323830381 cites W2016900251 @default.
• W4323830381 cites W2027539046 @default.
• W4323830381 cites W2038290790 @default.
• W4323830381 cites W2052590294 @default.
• W4323830381 cites W2059546701 @default.
• W4323830381 cites W2072773791 @default.
• W4323830381 cites W2110032258 @default.
• W4323830381 cites W2111653126 @default.
• W4323830381 cites W2121985347 @default.
• W4323830381 cites W2132001513 @default.
• W4323830381 cites W2138177802 @default.
• W4323830381 cites W2159537989 @default.
• W4323830381 cites W2169840662 @default.
• W4323830381 cites W2170806255 @default.
• W4323830381 cites W2283591591 @default.
• W4323830381 cites W2328237475 @default.
• W4323830381 cites W2341793557 @default.
• W4323830381 cites W2945722290 @default.
• W4323830381 cites W3080466546 @default.
• W4323830381 cites W3088395189 @default.
• W4323830381 cites W4241211581 @default.
• W4323830381 cites W4247261313 @default.
• W4323830381 cites W4293258489 @default.
• W4323830381 doi "https://doi.org/10.1016/j.jse.2023.02.119" @default.
• W4323830381 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36907317" @default.
• W4323830381 hasPublicationYear "2023" @default.
• W4323830381 type Work @default.
• W4323830381 citedByCount "1" @default.
• W4323830381 countsByYear W43238303812023 @default.
• W4323830381 crossrefType "journal-article" @default.
• W4323830381 hasAuthorship W4323830381A5043937771 @default.
• W4323830381 hasAuthorship W4323830381A5050130174 @default.
• W4323830381 hasAuthorship W4323830381A5074392564 @default.
• W4323830381 hasAuthorship W4323830381A5079130465 @default.
• W4323830381 hasAuthorship W4323830381A5084393145 @default.
• W4323830381 hasAuthorship W4323830381A5085053259 @default.
• W4323830381 hasConcept C141071460 @default.
• W4323830381 hasConcept C142724271 @default.
• W4323830381 hasConcept C168563851 @default.
• W4323830381 hasConcept C204787440 @default.
• W4323830381 hasConcept C27081682 @default.
• W4323830381 hasConcept C2778842504 @default.
• W4323830381 hasConcept C2779330695 @default.
• W4323830381 hasConcept C2780650075 @default.
• W4323830381 hasConcept C2781184374 @default.
• W4323830381 hasConcept C60465272 @default.
• W4323830381 hasConcept C71924100 @default.
• W4323830381 hasConcept C81182388 @default.
• W4323830381 hasConceptScore W4323830381C141071460 @default.
• W4323830381 hasConceptScore W4323830381C142724271 @default.
• W4323830381 hasConceptScore W4323830381C168563851 @default.
• W4323830381 hasConceptScore W4323830381C204787440 @default.
• W4323830381 hasConceptScore W4323830381C27081682 @default.
• W4323830381 hasConceptScore W4323830381C2778842504 @default.
• W4323830381 hasConceptScore W4323830381C2779330695 @default.
• W4323830381 hasConceptScore W4323830381C2780650075 @default.
• W4323830381 hasConceptScore W4323830381C2781184374 @default.
• W4323830381 hasConceptScore W4323830381C60465272 @default.
• W4323830381 hasConceptScore W4323830381C71924100 @default.
• W4323830381 hasConceptScore W4323830381C81182388 @default.
• W4323830381 hasFunder F4320319981 @default.
• W4323830381 hasIssue "6" @default.
• W4323830381 hasLocation W43238303811 @default.
• W4323830381 hasLocation W43238303812 @default.
• W4323830381 hasOpenAccess W4323830381 @default.
• W4323830381 hasPrimaryLocation W43238303811 @default.
• W4323830381 hasRelatedWork W2135683537 @default.
• W4323830381 hasRelatedWork W2210436481 @default.
• W4323830381 hasRelatedWork W2461299373 @default.
• W4323830381 hasRelatedWork W2465397096 @default.
• W4323830381 hasRelatedWork W2465509053 @default.
• W4323830381 hasRelatedWork W2606283543 @default.
• W4323830381 hasRelatedWork W2624381957 @default.
• W4323830381 hasRelatedWork W3189634328 @default.
• W4323830381 hasRelatedWork W4233169298 @default.
• W4323830381 hasRelatedWork W4233907616 @default.
• W4323830381 hasVolume "32" @default.
• W4323830381 isParatext "false" @default.

• next