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- W4323924465 abstract "Bidirectional communication between astrocytes and neurons is essential for proper brain development. Astrocytes, a major glial cell type, are morphologically complex cells that directly interact with neuronal synapses to regulate synapse formation, maturation, and function. Astrocyte-secreted factors bind neuronal receptors to induce synaptogenesis with regional and circuit-level precision. Cell adhesion molecules mediate the direct contact between astrocytes and neurons, which is required for both synaptogenesis and astrocyte morphogenesis. Neuron-derived signals also shape astrocyte development, function, and molecular identity. This review highlights recent findings on the topic of astrocyte-synapse interactions, and discusses the importance of these interactions for synapse and astrocyte development." @default.
- W4323924465 created "2023-03-12" @default.
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- W4323924465 date "2023-06-01" @default.
- W4323924465 modified "2023-09-26" @default.
- W4323924465 title "Astrocyte-synapse interactions during brain development" @default.
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- W4323924465 doi "https://doi.org/10.1016/j.conb.2023.102704" @default.
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