FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4323971837> ?p ?o ?g. }

• W4323971837 abstract "At the group level, antidepressant efficacy of rTMS targets is inversely related to their normative connectivity with subgenual anterior cingulate cortex (sgACC). Individualized connectivity may yield better targets, particularly in patients with neuropsychiatric disorders who may have aberrant connectivity. However, sgACC connectivity shows poor test-retest reliability at the individual level. Individualized resting-state network mapping (RSNM) can reliably map inter-individual variability in brain network organization. Thus, we sought to identify individualized RSNM-based rTMS targets that reliably target the sgACC connectivity profile. We used RSNM to identify network-based rTMS targets in 10 healthy controls and 13 individuals with traumatic brain injury-associated depression (TBI-D). These RSNM targets were compared with consensus structural targets and targets based on individualized anti-correlation with a group-mean-derived sgACC region (sgACC-derived targets). The TBI-D cohort was also randomized to receive active (n = 9) or sham (n = 4) rTMS to RSNM targets with 20 daily sessions of sequential high-frequency left-sided stimulation and low-frequency right-sided stimulation. We found that the group-mean sgACC connectivity profile was reliably estimated by individualized correlation with default mode network (DMN) and anti-correlation with dorsal attention network (DAN). Individualized RSNM targets were thus identified based on DAN anti-correlation and DMN correlation. These RSNM targets showed greater test-retest reliability than sgACC-derived targets. Counterintuitively, anti-correlation with the group-mean sgACC connectivity profile was also stronger and more reliable for RSNM-derived targets than for sgACC-derived targets. Improvement in depression after RSNM-targeted rTMS was predicted by target anti-correlation with the portions of sgACC. Active treatment also led to increased connectivity within and between the stimulation sites, the sgACC, and the DMN. Overall, these results suggest that RSNM may enable reliable individualized rTMS targeting, although further research is needed to determine whether this personalized approach can improve clinical outcomes." @default.
• W4323971837 created "2023-03-13" @default.
• W4323971837 creator A5023102775 @default.
• W4323971837 creator A5039000139 @default.
• W4323971837 creator A5051232039 @default.
• W4323971837 creator A5065549626 @default.
• W4323971837 creator A5077868821 @default.
• W4323971837 creator A5083123768 @default.
• W4323971837 creator A5089440639 @default.
• W4323971837 date "2023-03-11" @default.
• W4323971837 modified "2023-10-07" @default.
• W4323971837 title "Individualized precision targeting of dorsal attention and default mode networks with rTMS in traumatic brain injury-associated depression" @default.
• W4323971837 cites W1687468892 @default.
• W4323971837 cites W1760829075 @default.
• W4323971837 cites W1798863236 @default.
• W4323971837 cites W1939848850 @default.
• W4323971837 cites W1973776237 @default.
• W4323971837 cites W1983306600 @default.
• W4323971837 cites W1987464027 @default.
• W4323971837 cites W1988751658 @default.
• W4323971837 cites W2004874491 @default.
• W4323971837 cites W2012214808 @default.
• W4323971837 cites W2020519533 @default.
• W4323971837 cites W2043601923 @default.
• W4323971837 cites W2046558738 @default.
• W4323971837 cites W2053371208 @default.
• W4323971837 cites W2067456724 @default.
• W4323971837 cites W2082714165 @default.
• W4323971837 cites W2083345043 @default.
• W4323971837 cites W2084892943 @default.
• W4323971837 cites W2095438393 @default.
• W4323971837 cites W2131398580 @default.
• W4323971837 cites W2147149374 @default.
• W4323971837 cites W2156131484 @default.
• W4323971837 cites W2178864546 @default.
• W4323971837 cites W2212967118 @default.
• W4323971837 cites W2217735167 @default.
• W4323971837 cites W2277151310 @default.
• W4323971837 cites W2403664975 @default.
• W4323971837 cites W2411403931 @default.
• W4323971837 cites W2416745659 @default.
• W4323971837 cites W2499800833 @default.
• W4323971837 cites W2519753596 @default.
• W4323971837 cites W2557111525 @default.
• W4323971837 cites W2557389670 @default.
• W4323971837 cites W2569748607 @default.
• W4323971837 cites W2581778384 @default.
• W4323971837 cites W2741941708 @default.
• W4323971837 cites W2767756464 @default.
• W4323971837 cites W2793193004 @default.
• W4323971837 cites W2897818046 @default.
• W4323971837 cites W2898834153 @default.
• W4323971837 cites W2909133769 @default.
• W4323971837 cites W2932951493 @default.
• W4323971837 cites W2951617899 @default.
• W4323971837 cites W3015170488 @default.
• W4323971837 cites W3033781588 @default.
• W4323971837 cites W3109502500 @default.
• W4323971837 cites W3126445049 @default.
• W4323971837 cites W3149188702 @default.
• W4323971837 cites W3181719595 @default.
• W4323971837 cites W3208689015 @default.
• W4323971837 cites W4224212725 @default.
• W4323971837 doi "https://doi.org/10.1038/s41598-022-21905-x" @default.
• W4323971837 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36906616" @default.
• W4323971837 hasPublicationYear "2023" @default.
• W4323971837 type Work @default.
• W4323971837 citedByCount "3" @default.
• W4323971837 countsByYear W43239718372023 @default.
• W4323971837 crossrefType "journal-article" @default.
• W4323971837 hasAuthorship W4323971837A5023102775 @default.
• W4323971837 hasAuthorship W4323971837A5039000139 @default.
• W4323971837 hasAuthorship W4323971837A5051232039 @default.
• W4323971837 hasAuthorship W4323971837A5065549626 @default.
• W4323971837 hasAuthorship W4323971837A5077868821 @default.
• W4323971837 hasAuthorship W4323971837A5083123768 @default.
• W4323971837 hasAuthorship W4323971837A5089440639 @default.
• W4323971837 hasBestOaLocation W43239718371 @default.
• W4323971837 hasConcept C141516989 @default.
• W4323971837 hasConcept C15744967 @default.
• W4323971837 hasConcept C169760540 @default.
• W4323971837 hasConcept C3018011982 @default.
• W4323971837 hasConcept C47107517 @default.
• W4323971837 hasConceptScore W4323971837C141516989 @default.
• W4323971837 hasConceptScore W4323971837C15744967 @default.
• W4323971837 hasConceptScore W4323971837C169760540 @default.
• W4323971837 hasConceptScore W4323971837C3018011982 @default.
• W4323971837 hasConceptScore W4323971837C47107517 @default.
• W4323971837 hasFunder F4320332884 @default.
• W4323971837 hasIssue "1" @default.
• W4323971837 hasLocation W43239718371 @default.
• W4323971837 hasLocation W43239718372 @default.
• W4323971837 hasLocation W43239718373 @default.
• W4323971837 hasLocation W43239718374 @default.
• W4323971837 hasLocation W43239718375 @default.
• W4323971837 hasLocation W43239718376 @default.
• W4323971837 hasOpenAccess W4323971837 @default.
• W4323971837 hasPrimaryLocation W43239718371 @default.
• W4323971837 hasRelatedWork W2042557239 @default.
• W4323971837 hasRelatedWork W2154471387 @default.

• next