FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4324017543> ?p ?o ?g. }

• W4324017543 endingPage "e439" @default.
• W4324017543 startingPage "e430" @default.
• W4324017543 abstract "Introduction: The aim of the current randomized control trial was to assess the efficacy of donor lifestyle optimization on liver regeneration and outcome following live donor liver transplantation. Methods: Live liver donors (LLDs) who were fit with no or minimal steatosis were randomized to receive either a customized low-calorie diet with calorie intake equalling their basal requirement along with exercise for 2 weeks before surgery versus to continue their normal routine lifestyle. Primary objectives were the difference in the day of normalization of serum bilirubin and PT-International normalized ratio and the percentage growth of the liver at postoperative day 7 and 14. Secondary objectives were differences in intraoperative liver biopsy, liver-regeneration markers, blood loss, hospital stay, the complication rate in LLDs, and rates of early graft dysfunction (EGD) in recipients. Results: Sixty-two consecutive LLDs were randomized (28 in intervention vs. 34 in control). Baseline parameters and graft parameters were similar in both groups. LLDs in the intervention arm had significantly decreased calorie intake ( P <0.005), abdominal girth ( P <0.005), BMI ( P =0.05), and weight ( P <0.0005). The mean blood loss ( P =0.038), day of normalization of bilirubin ( P =0.005) and International normalized ratio ( P =0.061), postoperative peak aspartate transaminase ( P =0.003), Alanine transaminase ( P =0.025), and steatosis ( P <0.005) were significantly less in the intervention group. There was significantly higher volume regeneration ( P =0.03) in donors in the intervention arm. The levels of TNF-α, IL-6, and IL-10 levels were significantly higher, while the TGF-β level was lower in donors in the intervention group. The rate of EGD was significantly higher in recipients in the control group ( P =0.043). Conclusion: Lifestyle optimization of LLD is simple to comply with, improves liver regeneration in LLDs, and decreases EGD in recipients, thus can enhance donor safety and outcomes in live donor liver transplantation." @default.
• W4324017543 created "2023-03-14" @default.
• W4324017543 creator A5006608143 @default.
• W4324017543 creator A5010639369 @default.
• W4324017543 creator A5016551308 @default.
• W4324017543 creator A5023084546 @default.
• W4324017543 creator A5049994962 @default.
• W4324017543 creator A5053632477 @default.
• W4324017543 creator A5066004878 @default.
• W4324017543 creator A5083912048 @default.
• W4324017543 date "2023-03-13" @default.
• W4324017543 modified "2023-10-11" @default.
• W4324017543 title "Lifestyle Optimization Leads to Superior Liver Regeneration in Live Liver Donors and Decreases Early Allograft Dysfunction in Recipients" @default.
• W4324017543 cites W2011254995 @default.
• W4324017543 cites W2025421728 @default.
• W4324017543 cites W2026413826 @default.
• W4324017543 cites W2026943309 @default.
• W4324017543 cites W2031915073 @default.
• W4324017543 cites W2035197720 @default.
• W4324017543 cites W2038363057 @default.
• W4324017543 cites W2043493252 @default.
• W4324017543 cites W2046994269 @default.
• W4324017543 cites W2053271620 @default.
• W4324017543 cites W2055074097 @default.
• W4324017543 cites W2074884787 @default.
• W4324017543 cites W2096998881 @default.
• W4324017543 cites W2124862301 @default.
• W4324017543 cites W2141478654 @default.
• W4324017543 cites W2168396443 @default.
• W4324017543 cites W2177334078 @default.
• W4324017543 cites W2300401690 @default.
• W4324017543 cites W2301045679 @default.
• W4324017543 cites W2420394762 @default.
• W4324017543 cites W2488062557 @default.
• W4324017543 cites W2774108532 @default.
• W4324017543 cites W2792185404 @default.
• W4324017543 cites W2998474645 @default.
• W4324017543 cites W3000728513 @default.
• W4324017543 cites W3147209082 @default.
• W4324017543 cites W3160178839 @default.
• W4324017543 cites W4214898629 @default.
• W4324017543 cites W4221108291 @default.
• W4324017543 doi "https://doi.org/10.1097/sla.0000000000005836" @default.
• W4324017543 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36912445" @default.
• W4324017543 hasPublicationYear "2023" @default.
• W4324017543 type Work @default.
• W4324017543 citedByCount "3" @default.
• W4324017543 countsByYear W43240175432023 @default.
• W4324017543 crossrefType "journal-article" @default.
• W4324017543 hasAuthorship W4324017543A5006608143 @default.
• W4324017543 hasAuthorship W4324017543A5010639369 @default.
• W4324017543 hasAuthorship W4324017543A5016551308 @default.
• W4324017543 hasAuthorship W4324017543A5023084546 @default.
• W4324017543 hasAuthorship W4324017543A5049994962 @default.
• W4324017543 hasAuthorship W4324017543A5053632477 @default.
• W4324017543 hasAuthorship W4324017543A5066004878 @default.
• W4324017543 hasAuthorship W4324017543A5083912048 @default.
• W4324017543 hasConcept C126322002 @default.
• W4324017543 hasConcept C126894567 @default.
• W4324017543 hasConcept C141071460 @default.
• W4324017543 hasConcept C160160445 @default.
• W4324017543 hasConcept C168563851 @default.
• W4324017543 hasConcept C181199279 @default.
• W4324017543 hasConcept C185592680 @default.
• W4324017543 hasConcept C2776175330 @default.
• W4324017543 hasConcept C2778606649 @default.
• W4324017543 hasConcept C2779609443 @default.
• W4324017543 hasConcept C2779679107 @default.
• W4324017543 hasConcept C2911091166 @default.
• W4324017543 hasConcept C40438245 @default.
• W4324017543 hasConcept C55493867 @default.
• W4324017543 hasConcept C71924100 @default.
• W4324017543 hasConcept C90924648 @default.
• W4324017543 hasConceptScore W4324017543C126322002 @default.
• W4324017543 hasConceptScore W4324017543C126894567 @default.
• W4324017543 hasConceptScore W4324017543C141071460 @default.
• W4324017543 hasConceptScore W4324017543C160160445 @default.
• W4324017543 hasConceptScore W4324017543C168563851 @default.
• W4324017543 hasConceptScore W4324017543C181199279 @default.
• W4324017543 hasConceptScore W4324017543C185592680 @default.
• W4324017543 hasConceptScore W4324017543C2776175330 @default.
• W4324017543 hasConceptScore W4324017543C2778606649 @default.
• W4324017543 hasConceptScore W4324017543C2779609443 @default.
• W4324017543 hasConceptScore W4324017543C2779679107 @default.
• W4324017543 hasConceptScore W4324017543C2911091166 @default.
• W4324017543 hasConceptScore W4324017543C40438245 @default.
• W4324017543 hasConceptScore W4324017543C55493867 @default.
• W4324017543 hasConceptScore W4324017543C71924100 @default.
• W4324017543 hasConceptScore W4324017543C90924648 @default.
• W4324017543 hasIssue "3" @default.
• W4324017543 hasLocation W43240175431 @default.
• W4324017543 hasLocation W43240175432 @default.
• W4324017543 hasOpenAccess W4324017543 @default.
• W4324017543 hasPrimaryLocation W43240175431 @default.
• W4324017543 hasRelatedWork W2064782442 @default.
• W4324017543 hasRelatedWork W2076204761 @default.
• W4324017543 hasRelatedWork W2745950292 @default.
• W4324017543 hasRelatedWork W2755533190 @default.

• next