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• W4324020217 abstract "Summary Objective Birth weight (BW) and sibling's status are two important indicators of early intrauterine environment and subsequent living environment, but no evidence has emerged on their joint associations on metabolic obesity phenotype. To determine the joint associations between BW and single‐child status with childhood metabolic obesity phenotype was our purpose. Methods A cross‐sectional assessment of children and adolescents aged 7–18 years was performed in Chinese seven provinces in 2013. We obtained anthropometric, blood pressure and biochemical measurements, and distributed questionnaires covering demographic, neonatal and lifestyle characteristics. The metabolic obesity phenotype was defined by 2018 consensus‐based criteria. Logistic regression and restricted cubic spline models were applied to evaluate the associations of BW and metabolic obesity phenotype, and estimate the multiplicative interactions and the combined associations of BW and single‐child status with metabolic obesity phenotype. Results Of enrolled 12 346 children and adolescents, the prevalence of metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUO) was 1.96% and 3.03%. There were 8.95% and 4.03% children with high BW or low BW, and 67.55% did not have siblings. High BW was positively associated with MHO (OR = 1.94, 95%CI = 1.28–2.94). Single‐child also had increased odds of MHO and MUO ( p < 0.05), and it had joint associations with high BW showing 0.85‐ to 2.58‐fold higher odds of MUO and MHO. Conclusions High BW and single‐child status have joint positive associations with the subsequent odds of MHO and MUO, which should be jointly prevented through earlier screening and subsequent preventive strategies." @default.
• W4324020217 created "2023-03-14" @default.
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• W4324020217 date "2023-03-13" @default.
• W4324020217 modified "2023-09-26" @default.
• W4324020217 title "The joint associations of high birth weight and not having siblings with metabolic obesity phenotype among school‐aged children and adolescents: A National Survey in China" @default.
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• W4324020217 doi "https://doi.org/10.1111/ijpo.13021" @default.
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