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• W4324057237 abstract "Abstract Multiple myeloma (MM) is a common hematological malignancy resulting from clonal proliferation of plasma cells and is defined by criteria set forth by the international myeloma working group. Pulmonary hypertension (PH) is defined by an elevated mean pulmonary artery pressure >20 mmHg measured during right heart catheterization. Echocardiography‐diagnosed PH is relatively common in patients with MM and has been associated with increased mortality, morbidity, and poor stem cell transplant outcomes. PH in patients with MM (PH‐MM) is usually multifactorial in origin. MM disease‐specific factors, host comorbidities, and treatment‐related adverse effects are the key factors for the development of PH‐MM. Pragmatically, patients with PH‐MM can be grouped into either (i) PH in patients with a new diagnosis of MM or (ii) PH that develops or worsens along the way of MM treatment. In the latter group, drug‐induced PH, venous thromboembolism, pulmonary veno occlusive disease, and cardiotoxicity should be considered as possible causes. PH‐MM should be evaluated and managed in a multidisciplinary setting. Select individuals with PH‐MM could be considered for pulmonary vasodilators at PH‐specialized centers." @default.
• W4324057237 created "2023-03-14" @default.
• W4324057237 creator A5008427691 @default.
• W4324057237 creator A5021057037 @default.
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• W4324057237 creator A5080038357 @default.
• W4324057237 date "2023-04-01" @default.
• W4324057237 modified "2023-10-14" @default.
• W4324057237 title "Pulmonary hypertension in patients with multiple myeloma: A comprehensive review" @default.
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• W4324057237 doi "https://doi.org/10.1002/pul2.12210" @default.
• W4324057237 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37063748" @default.
• W4324057237 hasPublicationYear "2023" @default.
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