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- W4324091452 startingPage "2536" @default.
- W4324091452 abstract "Polyphenols are an important component of plant-derived food with a wide spectrum of beneficial effects on human health. For many years, they have aroused great interest, especially due to their antioxidant properties, which are used in the prevention and treatment of many diseases. Unfortunately, as with any chemical substance, depending on the conditions, dose, and interactions with the environment, it is possible for polyphenols to also exert harmful effects. This review presents a comprehensive current state of the knowledge on the negative impact of polyphenols on human health, describing the possible side effects of polyphenol intake, especially in the form of supplements. The review begins with a brief overview of the physiological role of polyphenols and their potential use in disease prevention, followed by the harmful effects of polyphenols which are exerted in particular situations. The individual chapters discuss the consequences of polyphenols’ ability to block iron uptake, which in some subpopulations can be harmful, as well as the possible inhibition of digestive enzymes, inhibition of intestinal microbiota, interactions of polyphenolic compounds with drugs, and impact on hormonal balance. Finally, the prooxidative activity of polyphenols as well as their mutagenic, carcinogenic, and genotoxic effects are presented. According to the authors, there is a need to raise public awareness about the possible side effects of polyphenols supplementation, especially in the case of vulnerable subpopulations." @default.
- W4324091452 created "2023-03-14" @default.
- W4324091452 creator A5009461188 @default.
- W4324091452 creator A5068916511 @default.
- W4324091452 date "2023-03-10" @default.
- W4324091452 modified "2023-10-14" @default.
- W4324091452 title "Possible Side Effects of Polyphenols and Their Interactions with Medicines" @default.
- W4324091452 cites W1025135529 @default.
- W4324091452 cites W123599737 @default.
- W4324091452 cites W1420654867 @default.
- W4324091452 cites W1480220150 @default.
- W4324091452 cites W1483916119 @default.
- W4324091452 cites W1484007224 @default.
- W4324091452 cites W1499468394 @default.
- W4324091452 cites W1507209789 @default.
- W4324091452 cites W1510773004 @default.
- W4324091452 cites W1524482367 @default.
- W4324091452 cites W1607110845 @default.
- W4324091452 cites W1619951972 @default.
- W4324091452 cites W1620958793 @default.
- W4324091452 cites W1812724700 @default.
- W4324091452 cites W1867730255 @default.
- W4324091452 cites W1899620471 @default.
- W4324091452 cites W1916061639 @default.
- W4324091452 cites W1955236246 @default.
- W4324091452 cites W1962199957 @default.
- W4324091452 cites W1963960348 @default.
- W4324091452 cites W1963989891 @default.
- W4324091452 cites W1965970124 @default.
- W4324091452 cites W1966521873 @default.
- W4324091452 cites W1966617502 @default.
- W4324091452 cites W1968107187 @default.
- W4324091452 cites W1968492952 @default.
- W4324091452 cites W1968826699 @default.
- W4324091452 cites W1968883627 @default.
- W4324091452 cites W1968962983 @default.
- W4324091452 cites W1970029118 @default.
- W4324091452 cites W1970318693 @default.
- W4324091452 cites W1970957969 @default.
- W4324091452 cites W1973607284 @default.
- W4324091452 cites W1974323405 @default.
- W4324091452 cites W1974797973 @default.
- W4324091452 cites W1977328678 @default.
- W4324091452 cites W1977403380 @default.
- W4324091452 cites W1978705334 @default.
- W4324091452 cites W1979161247 @default.
- W4324091452 cites W1980790707 @default.
- W4324091452 cites W1981753435 @default.
- W4324091452 cites W1983979341 @default.
- W4324091452 cites W1984573859 @default.
- W4324091452 cites W1985229938 @default.
- W4324091452 cites W1985378557 @default.
- W4324091452 cites W1987891029 @default.
- W4324091452 cites W1988587391 @default.
- W4324091452 cites W1988689918 @default.
- W4324091452 cites W1990734448 @default.
- W4324091452 cites W1991635559 @default.
- W4324091452 cites W1993846064 @default.
- W4324091452 cites W1994239064 @default.
- W4324091452 cites W1995851064 @default.
- W4324091452 cites W1996774772 @default.
- W4324091452 cites W1997431160 @default.
- W4324091452 cites W1998537166 @default.
- W4324091452 cites W1998647933 @default.
- W4324091452 cites W1999021046 @default.
- W4324091452 cites W2001145338 @default.
- W4324091452 cites W2001243940 @default.
- W4324091452 cites W2004037911 @default.
- W4324091452 cites W2006015545 @default.
- W4324091452 cites W2009351040 @default.
- W4324091452 cites W2010094251 @default.
- W4324091452 cites W2010350510 @default.
- W4324091452 cites W2011207510 @default.
- W4324091452 cites W2011821957 @default.
- W4324091452 cites W2012891747 @default.
- W4324091452 cites W2013759768 @default.
- W4324091452 cites W2013822904 @default.
- W4324091452 cites W2015013652 @default.
- W4324091452 cites W2015271663 @default.
- W4324091452 cites W2016398675 @default.
- W4324091452 cites W2016873500 @default.
- W4324091452 cites W2017115884 @default.
- W4324091452 cites W2017262942 @default.
- W4324091452 cites W2017668474 @default.
- W4324091452 cites W2017820158 @default.
- W4324091452 cites W2020286598 @default.
- W4324091452 cites W2021644716 @default.
- W4324091452 cites W2022997050 @default.
- W4324091452 cites W2023117579 @default.
- W4324091452 cites W2023352062 @default.
- W4324091452 cites W2023536393 @default.
- W4324091452 cites W2023689212 @default.
- W4324091452 cites W2024050667 @default.
- W4324091452 cites W2025577307 @default.
- W4324091452 cites W2026332374 @default.
- W4324091452 cites W2027331949 @default.
- W4324091452 cites W2027433336 @default.
- W4324091452 cites W2027633471 @default.