Matches in SemOpenAlex for { <https://semopenalex.org/work/W4324129874> ?p ?o ?g. }
- W4324129874 endingPage "521" @default.
- W4324129874 startingPage "505" @default.
- W4324129874 abstract "Alzheimer's disease (AD) is a neurodegenerative disease that gradually impairs cognitive functions. Recently, there has been a conceptual shift toward AD to view the disease as a continuum. Since AD is currently incurable, effective intervention to delay or prevent pathological cognitive decline may best target the early stages of symptomatic disease, such as subjective cognitive decline (SCD), in which cognitive function remains relatively intact. Diagnostic methods for identifying AD, such as cerebrospinal fluid biomarkers and positron emission tomography, are invasive and expensive. Therefore, it is imperative to develop blood biomarkers that are sensitive, less invasive, easier to access, and more cost effective for AD diagnosis. This review aimed to summarize the current data on whether individuals with SCD differ reliably and effectively in subjective and objective performances compared to cognitively normal elderly individuals, and to find one or more convenient and accessible blood biomarkers so that researchers can identify SCD patients with preclinical AD in the population as soon as possible. Owing to the heterogeneity and complicated pathogenesis of AD, it is difficult to make reliable diagnoses using only a single blood marker. This review provides an overview of the progress achieved to date with the use of SCD blood biomarkers in patients with preclinical AD, highlighting the key areas of application and current challenges." @default.
- W4324129874 created "2023-03-15" @default.
- W4324129874 creator A5006099594 @default.
- W4324129874 creator A5012792066 @default.
- W4324129874 creator A5021595106 @default.
- W4324129874 creator A5036663930 @default.
- W4324129874 creator A5066829203 @default.
- W4324129874 creator A5077980244 @default.
- W4324129874 creator A5084036897 @default.
- W4324129874 date "2023-03-05" @default.
- W4324129874 modified "2023-09-30" @default.
- W4324129874 title "Progress in blood biomarkers of subjective cognitive decline in preclinical Alzheimer's disease" @default.
- W4324129874 cites W1644143258 @default.
- W4324129874 cites W1978420618 @default.
- W4324129874 cites W2048505725 @default.
- W4324129874 cites W2115017507 @default.
- W4324129874 cites W2327547544 @default.
- W4324129874 cites W2470303519 @default.
- W4324129874 cites W2511591175 @default.
- W4324129874 cites W2557359439 @default.
- W4324129874 cites W2580678368 @default.
- W4324129874 cites W2590478248 @default.
- W4324129874 cites W2600914407 @default.
- W4324129874 cites W2736518852 @default.
- W4324129874 cites W2749148572 @default.
- W4324129874 cites W2785757836 @default.
- W4324129874 cites W2786797583 @default.
- W4324129874 cites W2787666045 @default.
- W4324129874 cites W2789976306 @default.
- W4324129874 cites W2792820766 @default.
- W4324129874 cites W2796227169 @default.
- W4324129874 cites W2798054687 @default.
- W4324129874 cites W2803086482 @default.
- W4324129874 cites W2805967580 @default.
- W4324129874 cites W2883286350 @default.
- W4324129874 cites W2889223700 @default.
- W4324129874 cites W2892024211 @default.
- W4324129874 cites W2899709077 @default.
- W4324129874 cites W2900969253 @default.
- W4324129874 cites W2902588987 @default.
- W4324129874 cites W2910313823 @default.
- W4324129874 cites W2910643217 @default.
- W4324129874 cites W2938221890 @default.
- W4324129874 cites W2939789416 @default.
- W4324129874 cites W2947800542 @default.
- W4324129874 cites W2952677120 @default.
- W4324129874 cites W2966365568 @default.
- W4324129874 cites W2971598158 @default.
- W4324129874 cites W2971621191 @default.
- W4324129874 cites W2983012175 @default.
- W4324129874 cites W2989531900 @default.
- W4324129874 cites W2998968185 @default.
- W4324129874 cites W2999941667 @default.
- W4324129874 cites W3003918230 @default.
- W4324129874 cites W3004767455 @default.
- W4324129874 cites W3006871825 @default.
- W4324129874 cites W3009441391 @default.
- W4324129874 cites W3012618838 @default.
- W4324129874 cites W3014487247 @default.
- W4324129874 cites W3017078364 @default.
- W4324129874 cites W3024239323 @default.
- W4324129874 cites W3043470682 @default.
- W4324129874 cites W3044633524 @default.
- W4324129874 cites W3047398819 @default.
- W4324129874 cites W3049140558 @default.
- W4324129874 cites W3083891838 @default.
- W4324129874 cites W3086656291 @default.
- W4324129874 cites W3093943691 @default.
- W4324129874 cites W3097328676 @default.
- W4324129874 cites W3098832816 @default.
- W4324129874 cites W3099667207 @default.
- W4324129874 cites W3102160053 @default.
- W4324129874 cites W3105808417 @default.
- W4324129874 cites W3106237074 @default.
- W4324129874 cites W3111871131 @default.
- W4324129874 cites W3114882165 @default.
- W4324129874 cites W3119309452 @default.
- W4324129874 cites W3119752846 @default.
- W4324129874 cites W3120817929 @default.
- W4324129874 cites W3123207203 @default.
- W4324129874 cites W3124395512 @default.
- W4324129874 cites W3131174931 @default.
- W4324129874 cites W3133275787 @default.
- W4324129874 cites W3152988830 @default.
- W4324129874 cites W3155371527 @default.
- W4324129874 cites W3160590222 @default.
- W4324129874 cites W3161967669 @default.
- W4324129874 cites W3165581912 @default.
- W4324129874 cites W3176315013 @default.
- W4324129874 cites W3177794462 @default.
- W4324129874 cites W3199026337 @default.
- W4324129874 cites W4200515458 @default.
- W4324129874 cites W4205106947 @default.
- W4324129874 cites W4206774749 @default.
- W4324129874 cites W4210761710 @default.
- W4324129874 cites W4220797074 @default.
- W4324129874 cites W4220825176 @default.
- W4324129874 cites W4225429728 @default.