Matches in SemOpenAlex for { <https://semopenalex.org/work/W4324140361> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W4324140361 abstract "Introduction: There is an association between thyroid autoimmunity and the cardiovascular system, however, it remains unclear whether detectability and positivity of thyroid peroxidase antibodies (TPOAb) could contribute to the development of atherosclerosis. Hypothesis: We assessed the hypothesis that there is an association of multiple categories of TPOAb with increased carotid intima-media thickness (cIMT) in participants from the ELSA-Brasil study. Methods: This is a cross-sectional study using baseline data of 9651 participants (mean age of 51.5 years-old, 55.8% women), without a history of cardiovascular disease. Fasting serum TPOAb levels were determined (Roche Diagnostics) and categorized as undetectable (≤ 5.00 IU/mL), low detectable (5.01-14.99 IU/mL), high detectable (15.00-33.99 IU/mL), and positive (34.00-600.00 IU/mL). Values of cIMT above the 75th percentile (≥0.68) were classified as “increased cIMT”. We performed logistic regression models, univariate and adjusted (for sex, age, BMI, smoking, alcohol consumption, diabetes, hypertension, dyslipidemia, and family history of cardiovascular disease), to determine odds ratio (OR) and 95% confidence intervals (CI). Results: Increased cIMT was prevalent in 24.4% of our sample, without statistically significant difference among the categories of TPOAb (p=0.066). Compared to undetectable TPOAb, low detectable category was associated with higher odds of having increased cIMT in univariate (OR=1.37, CI= 1.04-1.82) and remained associated after the adjustment for all confounders (OR=1.39, CI= 1.01-1.91). TPOAb high detectability was associated with increased cIMT only in the univariate (OR=1.40, CI= 1.04-1.88) and after adjustment for sex, age and BMI (OR=1.42, CI= 1.02-1.97). No association was seen for TPOAb positivity and cIMT (OR= 1.29, CI= 0.91-1.83). Conclusions: In conclusion, the modest association of low detectable TPOAb with cIMT may suggest a possible role of TPOAb in the atherosclerotic process." @default.
- W4324140361 created "2023-03-15" @default.
- W4324140361 creator A5008332341 @default.
- W4324140361 creator A5023008381 @default.
- W4324140361 creator A5024340971 @default.
- W4324140361 creator A5041755179 @default.
- W4324140361 creator A5048451318 @default.
- W4324140361 creator A5079168849 @default.
- W4324140361 creator A5088169254 @default.
- W4324140361 date "2023-02-28" @default.
- W4324140361 modified "2023-10-16" @default.
- W4324140361 title "Abstract P662: Thyroid Peroxidase Antibodies is Associated With Carotid Intima-Media Thickness in the Brazilian Longitudinal Study of Adult Health" @default.
- W4324140361 doi "https://doi.org/10.1161/circ.147.suppl_1.p662" @default.
- W4324140361 hasPublicationYear "2023" @default.
- W4324140361 type Work @default.
- W4324140361 citedByCount "0" @default.
- W4324140361 crossrefType "journal-article" @default.
- W4324140361 hasAuthorship W4324140361A5008332341 @default.
- W4324140361 hasAuthorship W4324140361A5023008381 @default.
- W4324140361 hasAuthorship W4324140361A5024340971 @default.
- W4324140361 hasAuthorship W4324140361A5041755179 @default.
- W4324140361 hasAuthorship W4324140361A5048451318 @default.
- W4324140361 hasAuthorship W4324140361A5079168849 @default.
- W4324140361 hasAuthorship W4324140361A5088169254 @default.
- W4324140361 hasConcept C126322002 @default.
- W4324140361 hasConcept C134018914 @default.
- W4324140361 hasConcept C144301174 @default.
- W4324140361 hasConcept C151956035 @default.
- W4324140361 hasConcept C156957248 @default.
- W4324140361 hasConcept C180650514 @default.
- W4324140361 hasConcept C2778096610 @default.
- W4324140361 hasConcept C2779134260 @default.
- W4324140361 hasConcept C2779339615 @default.
- W4324140361 hasConcept C2780176905 @default.
- W4324140361 hasConcept C2987047532 @default.
- W4324140361 hasConcept C38180746 @default.
- W4324140361 hasConcept C526584372 @default.
- W4324140361 hasConcept C555293320 @default.
- W4324140361 hasConcept C71924100 @default.
- W4324140361 hasConcept C77350462 @default.
- W4324140361 hasConcept C90924648 @default.
- W4324140361 hasConceptScore W4324140361C126322002 @default.
- W4324140361 hasConceptScore W4324140361C134018914 @default.
- W4324140361 hasConceptScore W4324140361C144301174 @default.
- W4324140361 hasConceptScore W4324140361C151956035 @default.
- W4324140361 hasConceptScore W4324140361C156957248 @default.
- W4324140361 hasConceptScore W4324140361C180650514 @default.
- W4324140361 hasConceptScore W4324140361C2778096610 @default.
- W4324140361 hasConceptScore W4324140361C2779134260 @default.
- W4324140361 hasConceptScore W4324140361C2779339615 @default.
- W4324140361 hasConceptScore W4324140361C2780176905 @default.
- W4324140361 hasConceptScore W4324140361C2987047532 @default.
- W4324140361 hasConceptScore W4324140361C38180746 @default.
- W4324140361 hasConceptScore W4324140361C526584372 @default.
- W4324140361 hasConceptScore W4324140361C555293320 @default.
- W4324140361 hasConceptScore W4324140361C71924100 @default.
- W4324140361 hasConceptScore W4324140361C77350462 @default.
- W4324140361 hasConceptScore W4324140361C90924648 @default.
- W4324140361 hasIssue "Suppl_1" @default.
- W4324140361 hasLocation W43241403611 @default.
- W4324140361 hasOpenAccess W4324140361 @default.
- W4324140361 hasPrimaryLocation W43241403611 @default.
- W4324140361 hasRelatedWork W1972113515 @default.
- W4324140361 hasRelatedWork W2002390752 @default.
- W4324140361 hasRelatedWork W2044797618 @default.
- W4324140361 hasRelatedWork W2088067906 @default.
- W4324140361 hasRelatedWork W2150335827 @default.
- W4324140361 hasRelatedWork W2164301666 @default.
- W4324140361 hasRelatedWork W2169697618 @default.
- W4324140361 hasRelatedWork W2322571913 @default.
- W4324140361 hasRelatedWork W2782964653 @default.
- W4324140361 hasRelatedWork W4362637518 @default.
- W4324140361 hasVolume "147" @default.
- W4324140361 isParatext "false" @default.
- W4324140361 isRetracted "false" @default.
- W4324140361 workType "article" @default.