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- W4324142207 abstract "Purpose: Autologous chondrocyte therapies have long been used to treat chondral/osteochondral defects and prevent the onset/progression of Osteoarthritis. There is a need, however, to move towards the use of allogeneic therapies. These can provide a single-step surgical intervention, with more scope to select chondrocytes with greatest potential to repair cartilage defects. Up-scale manufacture of allogeneic chondrocytes using a bioreactor may reduce the manufacturing costs and help to develop an off-the-shelf therapy. This study has assessed the Good Manufacturing Practice (GMP) compliant QuantumTM hollow-fibre bioreactor for chondrocyte manufacture using adult and juvenile cartilage donors." @default.
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- W4324142207 date "2023-03-01" @default.
- W4324142207 modified "2023-10-16" @default.
- W4324142207 title "Up-Scale Manufacture Of Chondrocytes From Adult And Juvenile Cartilage Donors For Allogeneic Chondrocyte Therapies" @default.
- W4324142207 doi "https://doi.org/10.1016/j.joca.2023.01.210" @default.
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