FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4324144328> ?p ?o ?g. }

• W4324144328 endingPage "1745" @default.
• W4324144328 startingPage "1745" @default.
• W4324144328 abstract "In newly diagnosed IDH-wildtype glioblastoma, the frequency and prognostic relevance of tumor regrowth between resection and the initiation of adjuvant radiochemotherapy are unclear. In this retrospective single-center study we included 64 consecutive cases, for whom magnetic resonance imaging (MRI) was available for both the volumetric assessment of the extent of resection immediately after surgery as well as the volumetric target delineation before the initiation of adjuvant radiochemotherapy (time interval: 15.5 ± 1.9 days). Overall, a median new contrast-enhancement volume was seen in 21/64 individuals (33%, 1.5 ± 1.5 cm3), and new non-contrast lesion volume in 18/64 patients (28%, 5.0 ± 2.3 cm3). A multidisciplinary in-depth review revealed that new contrast-enhancement was either due to (I) the progression of contrast-enhancing tumor remnants in 6/21 patients or (II) distant contrast-enhancing foci or breakdown of the blood-brain barrier in previously non-contrast-enhancing tumor remnants in 5/21 patients, whereas it was unspecific or due to ischemia in 10/21 patients. For non-contrast-enhancing lesions, three of eighteen had progression of non-contrast-enhancing tumor remnants and fifteen of eighteen had unspecific changes or changes due to ischemia. There was no significant association between findings consistent with tumor regrowth and a less favorable outcome (overall survival: 14 vs. 19 months; p = 0.423). These findings support the rationale that analysis of the postsurgical remaining tumor-volume for prognostic stratification should be carried out on immediate postoperative MRI (<72 h), as unspecific changes are common. However, tumor regrowth including distant foci may occur in a subset of IDH-wildtype glioblastoma patients diagnosed per WHO 2021 classification. Thus, MRI imaging prior to radiotherapy should be obtained to adjust radiotherapy planning accordingly." @default.
• W4324144328 created "2023-03-15" @default.
• W4324144328 creator A5011416942 @default.
• W4324144328 creator A5013875638 @default.
• W4324144328 creator A5025596436 @default.
• W4324144328 creator A5036243661 @default.
• W4324144328 creator A5038323479 @default.
• W4324144328 creator A5050738411 @default.
• W4324144328 creator A5065547065 @default.
• W4324144328 creator A5074844284 @default.
• W4324144328 date "2023-03-14" @default.
• W4324144328 modified "2023-09-25" @default.
• W4324144328 title "Frequency and Prognostic Relevance of Volumetric MRI Changes in Contrast- and Non-Contrast-Enhancing Tumor Compartments between Surgery and Radiotherapy of IDHwt Glioblastoma" @default.
• W4324144328 cites W2076421854 @default.
• W4324144328 cites W2096287682 @default.
• W4324144328 cites W2118340846 @default.
• W4324144328 cites W2125372543 @default.
• W4324144328 cites W2162643152 @default.
• W4324144328 cites W2164705247 @default.
• W4324144328 cites W2228626376 @default.
• W4324144328 cites W2299310271 @default.
• W4324144328 cites W2332430608 @default.
• W4324144328 cites W2575948927 @default.
• W4324144328 cites W2618498448 @default.
• W4324144328 cites W2778283729 @default.
• W4324144328 cites W2806673781 @default.
• W4324144328 cites W2807341704 @default.
• W4324144328 cites W2811036728 @default.
• W4324144328 cites W2914199948 @default.
• W4324144328 cites W2939765841 @default.
• W4324144328 cites W3005337228 @default.
• W4324144328 cites W3020099303 @default.
• W4324144328 cites W3039867476 @default.
• W4324144328 cites W3083421441 @default.
• W4324144328 cites W3110787789 @default.
• W4324144328 cites W3174246647 @default.
• W4324144328 cites W4200415836 @default.
• W4324144328 cites W4200464615 @default.
• W4324144328 cites W4281631855 @default.
• W4324144328 cites W4290930135 @default.
• W4324144328 cites W4297996029 @default.
• W4324144328 cites W4301595791 @default.
• W4324144328 doi "https://doi.org/10.3390/cancers15061745" @default.
• W4324144328 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36980633" @default.
• W4324144328 hasPublicationYear "2023" @default.
• W4324144328 type Work @default.
• W4324144328 citedByCount "1" @default.
• W4324144328 countsByYear W43241443282023 @default.
• W4324144328 crossrefType "journal-article" @default.
• W4324144328 hasAuthorship W4324144328A5011416942 @default.
• W4324144328 hasAuthorship W4324144328A5013875638 @default.
• W4324144328 hasAuthorship W4324144328A5025596436 @default.
• W4324144328 hasAuthorship W4324144328A5036243661 @default.
• W4324144328 hasAuthorship W4324144328A5038323479 @default.
• W4324144328 hasAuthorship W4324144328A5050738411 @default.
• W4324144328 hasAuthorship W4324144328A5065547065 @default.
• W4324144328 hasAuthorship W4324144328A5074844284 @default.
• W4324144328 hasBestOaLocation W43241443281 @default.
• W4324144328 hasConcept C126838900 @default.
• W4324144328 hasConcept C142724271 @default.
• W4324144328 hasConcept C143409427 @default.
• W4324144328 hasConcept C154945302 @default.
• W4324144328 hasConcept C2776194525 @default.
• W4324144328 hasConcept C2776502983 @default.
• W4324144328 hasConcept C2989005 @default.
• W4324144328 hasConcept C41008148 @default.
• W4324144328 hasConcept C502942594 @default.
• W4324144328 hasConcept C509974204 @default.
• W4324144328 hasConcept C63363279 @default.
• W4324144328 hasConcept C71924100 @default.
• W4324144328 hasConceptScore W4324144328C126838900 @default.
• W4324144328 hasConceptScore W4324144328C142724271 @default.
• W4324144328 hasConceptScore W4324144328C143409427 @default.
• W4324144328 hasConceptScore W4324144328C154945302 @default.
• W4324144328 hasConceptScore W4324144328C2776194525 @default.
• W4324144328 hasConceptScore W4324144328C2776502983 @default.
• W4324144328 hasConceptScore W4324144328C2989005 @default.
• W4324144328 hasConceptScore W4324144328C41008148 @default.
• W4324144328 hasConceptScore W4324144328C502942594 @default.
• W4324144328 hasConceptScore W4324144328C509974204 @default.
• W4324144328 hasConceptScore W4324144328C63363279 @default.
• W4324144328 hasConceptScore W4324144328C71924100 @default.
• W4324144328 hasIssue "6" @default.
• W4324144328 hasLocation W43241443281 @default.
• W4324144328 hasLocation W43241443282 @default.
• W4324144328 hasLocation W43241443283 @default.
• W4324144328 hasOpenAccess W4324144328 @default.
• W4324144328 hasPrimaryLocation W43241443281 @default.
• W4324144328 hasRelatedWork W2036862336 @default.
• W4324144328 hasRelatedWork W2049214470 @default.
• W4324144328 hasRelatedWork W2113200719 @default.
• W4324144328 hasRelatedWork W2162041988 @default.
• W4324144328 hasRelatedWork W2384708512 @default.
• W4324144328 hasRelatedWork W2740663609 @default.
• W4324144328 hasRelatedWork W2741705607 @default.
• W4324144328 hasRelatedWork W2902148150 @default.
• W4324144328 hasRelatedWork W3032055452 @default.
• W4324144328 hasRelatedWork W4214789906 @default.

• next