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- W4324258819 abstract "Pancreatic neuroendocrine tumors (PNETs) occur in < 1/100,000 patients and most are nonfunctioning (NF). Approximately 5% occur as part of multiple endocrine neoplasia type 1. Anatomic and molecular imaging have a pivotal role in the diagnosis, staging and active surveillance. Surgery is generally recommended for nonfunctional pancreatic neuroendocrine tumors (NF-PNETs) >2 cm to prevent metastases. For tumors ≤2 cm, active surveillance is a viable alternative. Tumor size and grade are important factors to guide management. Assessment of death domain-associated protein 6/alpha-thalassemia/mental retardation X-linked and alternative lengthening of telomeres are promising novel prognostic markers. This review summarizes the status of surveillance and nonsurgical management for small NF-PNETs, including factors that can guide management." @default.
- W4324258819 created "2023-03-15" @default.
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- W4324258819 date "2023-04-01" @default.
- W4324258819 modified "2023-10-18" @default.
- W4324258819 title "Status of Surveillance and Nonsurgical Therapy for Small Nonfunctioning Pancreatic Neuroendocrine Tumors" @default.
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- W4324258819 doi "https://doi.org/10.1016/j.soc.2022.10.010" @default.
- W4324258819 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36925190" @default.
- W4324258819 hasPublicationYear "2023" @default.
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