Matches in SemOpenAlex for { <https://semopenalex.org/work/W4327584893> ?p ?o ?g. }
- W4327584893 abstract "The aim of this study was to investigate the risk factors for lymph node metastasis (LNM) in patients with uterine serous cancer (USC) who underwent systematic staging surgery. Eighty patients who were operated on for pure uterine serous papillary carcinoma between 2008 and 2020 in our clinic were retrospectively analysed. The effects of demographic information and clinicohistopathological characteristics of the included patients on LNM were examined. The median age of the patients included in the study was 64.3 and the tumour diameter was 3.8 cm. At the time of diagnosis, 65.8% of the cases were in the advanced stage, while 34.2% were in the early stage. There was no LNM in 42 (52.5%) of the cases, only pelvic in six (7.5%), only paraaortic LNM in four (5%) patients, and both pelvic and paraaortic LNM in 24 (30%) patients. When factors that may affect LNM were evaluated with multivariate analysis, lymphovascular space invasion (LVSI) and cytology positivity were found to be independent risk factors (p < 0.05). In addition, the rate of isolated paraaortic lymph node involvement in LNM positive patients is 5%, which is 100% associated with LVSI.Impact StatementWhat is already known on this subject? Uterine papillary serous carcinomas (UPSC) are an uncommon and aggressive histological subtype of endometrial cancer. The high risk of recurrence and tendency to migrate into the abdomen of these tumours is not always connected with lymph node and distant organ metastasis, tumour size, LVSI positive and depth of myometrial invasion.What do the results of this study add? Most patients with UPSC are diagnosed at an advanced stage. In this study, in which 80 patients with pure serous histology were evaluated retrospectively, and LVSI and peritoneal cytology positivity were found to be two important prognostic factors for lymph node metastasis.What are the implications of these findings for clinical practice and/or further research? In this study, cytology and LVSI positivity were identified as two predictive markers for LNM, and it is seen that cytology positivity still maintains its importance in these tumours with peritoneal spread. Furthermore, patients with isolated paraaortic lymph node involvement were shown to be LVSI positive, and isolated paraaortic LNM should be investigated in patients with LVSI positivity." @default.
- W4327584893 created "2023-03-17" @default.
- W4327584893 creator A5049925359 @default.
- W4327584893 creator A5050527485 @default.
- W4327584893 creator A5074375489 @default.
- W4327584893 date "2023-03-16" @default.
- W4327584893 modified "2023-09-26" @default.
- W4327584893 title "Factor affecting lymph node metastasis in uterine papillary serous carcinomas: a retrospective analysis" @default.
- W4327584893 cites W144188814 @default.
- W4327584893 cites W158172068 @default.
- W4327584893 cites W1905054492 @default.
- W4327584893 cites W1967085262 @default.
- W4327584893 cites W1968878817 @default.
- W4327584893 cites W1971007160 @default.
- W4327584893 cites W1983366035 @default.
- W4327584893 cites W1984251583 @default.
- W4327584893 cites W2007784474 @default.
- W4327584893 cites W2016294917 @default.
- W4327584893 cites W2021630849 @default.
- W4327584893 cites W2027546221 @default.
- W4327584893 cites W2041440766 @default.
- W4327584893 cites W2044869180 @default.
- W4327584893 cites W2054354334 @default.
- W4327584893 cites W2070608971 @default.
- W4327584893 cites W2070732782 @default.
- W4327584893 cites W2109451350 @default.
- W4327584893 cites W2150537368 @default.
- W4327584893 cites W2158349801 @default.
- W4327584893 cites W2159307123 @default.
- W4327584893 cites W2167865875 @default.
- W4327584893 cites W2182915546 @default.
- W4327584893 cites W2322366105 @default.
- W4327584893 cites W2327849424 @default.
- W4327584893 cites W2335319656 @default.
- W4327584893 cites W2514776617 @default.
- W4327584893 cites W2522350651 @default.
- W4327584893 cites W2558760568 @default.
- W4327584893 cites W2566141610 @default.
- W4327584893 cites W2615768554 @default.
- W4327584893 cites W2736245389 @default.
- W4327584893 cites W2787725515 @default.
- W4327584893 cites W2810271945 @default.
- W4327584893 cites W2907261502 @default.
- W4327584893 cites W2945208447 @default.
- W4327584893 cites W3024686453 @default.
- W4327584893 cites W4230574954 @default.
- W4327584893 cites W4378009821 @default.
- W4327584893 doi "https://doi.org/10.1080/01443615.2022.2158311" @default.
- W4327584893 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36927276" @default.
- W4327584893 hasPublicationYear "2023" @default.
- W4327584893 type Work @default.
- W4327584893 citedByCount "0" @default.
- W4327584893 crossrefType "journal-article" @default.
- W4327584893 hasAuthorship W4327584893A5049925359 @default.
- W4327584893 hasAuthorship W4327584893A5050527485 @default.
- W4327584893 hasAuthorship W4327584893A5074375489 @default.
- W4327584893 hasConcept C121608353 @default.
- W4327584893 hasConcept C126322002 @default.
- W4327584893 hasConcept C126838900 @default.
- W4327584893 hasConcept C143998085 @default.
- W4327584893 hasConcept C146357865 @default.
- W4327584893 hasConcept C150173356 @default.
- W4327584893 hasConcept C151730666 @default.
- W4327584893 hasConcept C167135981 @default.
- W4327584893 hasConcept C2777088508 @default.
- W4327584893 hasConcept C2779013556 @default.
- W4327584893 hasConcept C2780849966 @default.
- W4327584893 hasConcept C2781212463 @default.
- W4327584893 hasConcept C71924100 @default.
- W4327584893 hasConcept C86803240 @default.
- W4327584893 hasConceptScore W4327584893C121608353 @default.
- W4327584893 hasConceptScore W4327584893C126322002 @default.
- W4327584893 hasConceptScore W4327584893C126838900 @default.
- W4327584893 hasConceptScore W4327584893C143998085 @default.
- W4327584893 hasConceptScore W4327584893C146357865 @default.
- W4327584893 hasConceptScore W4327584893C150173356 @default.
- W4327584893 hasConceptScore W4327584893C151730666 @default.
- W4327584893 hasConceptScore W4327584893C167135981 @default.
- W4327584893 hasConceptScore W4327584893C2777088508 @default.
- W4327584893 hasConceptScore W4327584893C2779013556 @default.
- W4327584893 hasConceptScore W4327584893C2780849966 @default.
- W4327584893 hasConceptScore W4327584893C2781212463 @default.
- W4327584893 hasConceptScore W4327584893C71924100 @default.
- W4327584893 hasConceptScore W4327584893C86803240 @default.
- W4327584893 hasLocation W43275848931 @default.
- W4327584893 hasLocation W43275848932 @default.
- W4327584893 hasOpenAccess W4327584893 @default.
- W4327584893 hasPrimaryLocation W43275848931 @default.
- W4327584893 hasRelatedWork W138558693 @default.
- W4327584893 hasRelatedWork W1996923597 @default.
- W4327584893 hasRelatedWork W2044744112 @default.
- W4327584893 hasRelatedWork W2161160061 @default.
- W4327584893 hasRelatedWork W2913205700 @default.
- W4327584893 hasRelatedWork W3007849579 @default.
- W4327584893 hasRelatedWork W3127662523 @default.
- W4327584893 hasRelatedWork W3216080607 @default.
- W4327584893 hasRelatedWork W4231803726 @default.
- W4327584893 hasRelatedWork W4300604927 @default.
- W4327584893 isParatext "false" @default.
- W4327584893 isRetracted "false" @default.