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- W4327660090 abstract "Coronary heart disease is the most dangerous heart disease worldwide, and its morbidity and mortality rates are rising. Aspirin is the most clinically used anti-platelet-aggregation agent, preventing thrombosis and reducing the incidence of cardiovascular events. Accordingly, the development of drug-delivery systems containing aspirin is an urgent problem to be solved. In this study, PLGA microspheres with excellent biocompatibility were prepared based on the emulsification–volatilisation method by using aspirin as a drug model. PLGA/aspirin microspheres had small size, high sphericity, and high drug-loading rates. Its therapeutic activity and nursing application value against coronary heart disease were evaluated, and the related mechanism was explored." @default.
- W4327660090 created "2023-03-18" @default.
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- W4327660090 date "2022-12-01" @default.
- W4327660090 modified "2023-09-27" @default.
- W4327660090 title "Therapeutic Activity of Aspirin-Loaded Poly(lactic-co-glycolic acid) Microspheres Against Coronary Heart Disease" @default.
- W4327660090 doi "https://doi.org/10.1166/sam.2022.4386" @default.
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